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Cancer survival prediction is a challenging task that involves analyzing of the tumor microenvironment within Whole Slide Image (WSI). Previous methods cannot effectively capture the intricate interaction features among instances within the…

计算机视觉与模式识别 · 计算机科学 2024-10-23 Zekang Yang , Hong Liu , Xiangdong Wang

In the field of computational histopathology, both whole slide images (WSIs) and diagnostic captions provide valuable insights for making diagnostic decisions. However, aligning WSIs with diagnostic captions presents a significant…

计算机视觉与模式识别 · 计算机科学 2025-03-18 Qifeng Zhou , Wenliang Zhong , Yuzhi Guo , Michael Xiao , Hehuan Ma , Junzhou Huang

Weakly Supervised Object Detection (WSOD), using only image-level annotations to train object detectors, is of growing importance in object recognition. In this paper, we propose a novel deep network for WSOD. Unlike previous networks that…

计算机视觉与模式识别 · 计算机科学 2018-10-16 Peng Tang , Xinggang Wang , Song Bai , Wei Shen , Xiang Bai , Wenyu Liu , Alan Yuille

Supervised learning tasks such as cancer survival prediction from gigapixel whole slide images (WSIs) are a critical challenge in computational pathology that requires modeling complex features of the tumor microenvironment. These learning…

图像与视频处理 · 电气工程与系统科学 2022-11-22 Iain Carmichael , Andrew H. Song , Richard J. Chen , Drew F. K. Williamson , Tiffany Y. Chen , Faisal Mahmood

Multiple instance learning (MIL) has been widely used for representing whole-slide pathology images. However, spatial, semantic, and decision entanglements among instances limit its representation and interpretability. To address these…

计算机视觉与模式识别 · 计算机科学 2025-11-05 Chentao Li , Behzad Bozorgtabar , Yifang Ping , Pan Huang , Jing Qin

In the realm of digital pathology, multi-magnification Multiple Instance Learning (multi-mag MIL) has proven effective in leveraging the hierarchical structure of Whole Slide Images (WSIs) to reduce information loss and redundant data.…

计算机视觉与模式识别 · 计算机科学 2024-10-11 Yujian Liu , Ruoxuan Wu , Xinjie Shen , Zihuang Lu , Lingyu Liang , Haiyu Zhou , Shipu Xu , Shaoai Cai , Shidang Xu

The emergence of foundation models in computational pathology has transformed histopathological image analysis, with whole slide imaging (WSI) diagnosis being a core application. Traditionally, weakly supervised fine-tuning via multiple…

计算机视觉与模式识别 · 计算机科学 2025-03-03 Jiawen Li , Jiali Hu , Qiehe Sun , Renao Yan , Minxi Ouyang , Tian Guan , Anjia Han , Chao He , Yonghong He

Accurate lesion segmentation in histopathology images is essential for diagnostic interpretation and quantitative analysis, yet it remains challenging due to the limited availability of costly pixel-level annotations. To address this, we…

计算机视觉与模式识别 · 计算机科学 2025-06-10 Hangbei Cheng , Xiaorong Dong , Xueyu Liu , Jianan Zhang , Xuetao Ma , Mingqiang Wei , Liansheng Wang , Junxin Chen , Yongfei Wu

Whole-slide images (WSIs) are an important data modality in computational pathology, yet their gigapixel resolution and lack of fine-grained annotations challenge conventional deep learning models. Multiple instance learning (MIL) offers a…

计算机视觉与模式识别 · 计算机科学 2025-12-22 Qian Zeng , Yihui Wang , Shu Yang , Yingxue Xu , Fengtao Zhou , Jiabo Ma , Dejia Cai , Zhengyu Zhang , Lijuan Qu , Yu Wang , Li Liang , Hao Chen

Pretraining on large-scale, in-domain datasets grants histopathology foundation models (FM) the ability to learn task-agnostic data representations, enhancing transfer learning on downstream tasks. In computational pathology, automated…

计算机视觉与模式识别 · 计算机科学 2025-07-22 Pablo Meseguer , Rocío del Amor , Valery Naranjo

Weak supervision learning on classification labels has demonstrated high performance in various tasks, while a few pixel-level fine annotations are also affordable. Naturally a question comes to us that whether the combination of…

计算机视觉与模式识别 · 计算机科学 2021-10-26 Jiahui Li , Wen Chen , Xiaodi Huang , Zhiqiang Hu , Qi Duan , Hongsheng Li , Dimitris N. Metaxas , Shaoting Zhang

Whole slide images, with their gigapixel-scale panoramas of tissue samples, are pivotal for precise disease diagnosis. However, their analysis is hindered by immense data size and scarce annotations. Existing MIL methods face challenges due…

计算机视觉与模式识别 · 计算机科学 2026-02-26 Weiyi Wu , Xinwen Xu , Chongyang Gao , Xingjian Diao , Siting Li , Jiang Gui

Annotating cancerous regions in whole-slide images (WSIs) of pathology samples plays a critical role in clinical diagnosis, biomedical research, and machine learning algorithms development. However, generating exhaustive and accurate…

计算机视觉与模式识别 · 计算机科学 2022-06-09 Zhenzhen Wang , Carla Saoud , Sintawat Wangsiricharoen , Aaron W. James , Aleksander S. Popel , Jeremias Sulam

The abundance of information present in Whole Slide Images (WSIs) renders them an essential tool for survival analysis. Several Multiple Instance Learning frameworks proposed for this task utilize a ResNet50 backbone pre-trained on natural…

图像与视频处理 · 电气工程与系统科学 2025-08-05 Kleanthis Marios Papadopoulos , Tania Stathaki

In whole slide images (WSIs) analysis, attention-based multi-instance learning (MIL) models are susceptible to spurious correlations and degrade under domain shift. These methods may assign high attention weights to non-tumor regions, such…

计算机视觉与模式识别 · 计算机科学 2025-12-08 Xin Liu , Weijia Zhang , Wei Tang , Thuc Duy Le , Jiuyong Li , Lin Liu , Min-Ling Zhang

While Vision-Language Models (VLMs) have achieved notable progress in computational pathology (CPath), the gigapixel scale and spatial heterogeneity of Whole Slide Images (WSIs) continue to pose challenges for multimodal understanding.…

计算机视觉与模式识别 · 计算机科学 2025-12-22 Fengchun Liu , Songhan Jiang , Linghan Cai , Ziyue Wang , Yongbing Zhang

State-of-the-art audio event detection (AED) systems rely on supervised learning using strongly labeled data. However, this dependence severely limits scalability to large-scale datasets where fine resolution annotations are too expensive…

声音 · 计算机科学 2018-03-28 Shao-Yen Tseng , Juncheng Li , Yun Wang , Joseph Szurley , Florian Metze , Samarjit Das

Multiple Instance Learning (MIL) has emerged as a dominant paradigm to extract discriminative feature representations within Whole Slide Images (WSIs) in computational pathology. Despite driving notable progress, existing MIL approaches…

计算机视觉与模式识别 · 计算机科学 2024-03-12 Shu Yang , Yihui Wang , Hao Chen

Graph-based Multiple Instance Learning (MIL) is widely used in survival analysis with Hematoxylin and Eosin (H\&E)-stained whole slide images (WSIs) due to its ability to capture topological information. However, variations in staining and…

计算机视觉与模式识别 · 计算机科学 2025-09-25 Min Cen , Zhenfeng Zhuang , Yuzhe Zhang , Min Zeng , Baptiste Magnier , Lequan Yu , Hong Zhang , Liansheng Wang

Of late, weakly supervised object detection is with great importance in object recognition. Based on deep learning, weakly supervised detectors have achieved many promising results. However, compared with fully supervised detection, it is…

计算机视觉与模式识别 · 计算机科学 2017-04-04 Peng Tang , Xinggang Wang , Xiang Bai , Wenyu Liu