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Image registration is a fundamental medical image analysis task. Ideally, registration should focus on aligning semantically corresponding voxels, i.e., the same anatomical locations. However, existing methods often optimize similarity…

计算机视觉与模式识别 · 计算机科学 2024-02-27 Lin Tian , Zi Li , Fengze Liu , Xiaoyu Bai , Jia Ge , Le Lu , Marc Niethammer , Xianghua Ye , Ke Yan , Daikai Jin

Alzheimer's disease is a neurodegenerative condition that accelerates cognitive decline relative to normal aging. It is of critical scientific importance to gain a better understanding of early disease mechanisms in the brain to facilitate…

应用统计 · 统计学 2022-01-19 D. Andrew Brown , Christopher S. McMahan , Russell T. Shinohara , Kristin A. Linn

There is a need for automatic diagnosis of certain diseases from medical images that could help medical practitioners for further assessment towards treating the illness. Alzheimers disease is a good example of a disease that is often…

图像与视频处理 · 电气工程与系统科学 2019-01-30 GuruRaj Awate

Head magnetic resonance imaging (MRI) data are routinely collected and shared for research under strict regulatory frameworks that require the removal of direct identifiers prior to data release. However, even after skull stripping, brain…

计算机视觉与模式识别 · 计算机科学 2026-05-07 Gaurang Sharma , Harri Polonen , Juha Pajula , Jutta Suksi , Jussi Tohka

Building accurate and robust artificial intelligence systems for medical image assessment requires not only the research and design of advanced deep learning models but also the creation of large and curated sets of annotated training…

Alzheimer's disease (AD) confirmation often relies on positron emission tomography (PET) or cerebrospinal fluid (CSF) analysis, which are costly and invasive. Consequently, structural MRI biomarkers such as cortical thickness (CT) are…

计算机视觉与模式识别 · 计算机科学 2026-04-17 Geonwoo Baek , David H. Salat , Ikbeom Jang

The application of machine learning algorithms to the diagnosis and analysis of Alzheimer's disease (AD) from multimodal neuroimaging data is a current research hotspot. It remains a formidable challenge to learn brain region information…

图像与视频处理 · 电气工程与系统科学 2022-08-11 Yongcheng Zong , Changhong Jing , Qiankun Zuo

Mammographic screening is an effective method for detecting breast cancer, facilitating early diagnosis. However, the current need to manually inspect images places a heavy burden on healthcare systems, spurring a desire for automated…

图像与视频处理 · 电气工程与系统科学 2025-01-30 Ciaran Bench , Emir Ahmed , Spencer A. Thomas

To represent the biological variability of clinical neuroimaging populations, it is vital to be able to combine data across scanners and studies. However, different MRI scanners produce images with different characteristics, resulting in a…

计算机视觉与模式识别 · 计算机科学 2023-03-29 Nicola K Dinsdale , Mark Jenkinson , Ana IL Namburete

Limited amount of labelled training data are a common problem in medical imaging. This makes it difficult to train a well-generalised model and therefore often leads to failure in unknown domains. Hippocampus segmentation from magnetic…

图像与视频处理 · 电气工程与系统科学 2022-01-19 John Kalkhof , Camila González , Anirban Mukhopadhyay

Multimodal neuroimaging provides complementary structural and functional insights into both human brain organization and disease-related dynamics. Recent studies demonstrate enhanced diagnostic sensitivity for Alzheimer's disease (AD)…

多媒体 · 计算机科学 2025-04-24 Yuxiang Wei , Yanteng Zhang , Xi Xiao , Tianyang Wang , Xiao Wang , Vince D. Calhoun

Early and accurate diagnosis of Alzheimer's disease (AD) and its prodromal period mild cognitive impairment (MCI) is essential for the delayed disease progression and the improved quality of patients'life. The emerging computer-aided…

图像与视频处理 · 电气工程与系统科学 2021-07-29 Fan Zhang , Bo Pan , Pengfei Shao , Peng Liu , Shuwei Shen , Peng Yao , Ronald X. Xu

In clinical practice, medical segmentation datasets are often limited and heterogeneous, with variations in modalities, protocols, and anatomical targets across institutions. Existing deep learning models struggle to jointly learn from such…

计算机视觉与模式识别 · 计算机科学 2026-01-22 Weiwei Ma , Xiaobing Yu , Peijie Qiu , Jin Yang , Pan Xiao , Xiaoqi Zhao , Xiaofeng Liu , Tomo Miyazaki , Shinichiro Omachi , Yongsong Huang

Accurate segmentation of brain tissues from MRI scans is critical for neuroscience and clinical applications, but achieving consistent performance across the human lifespan remains challenging due to dynamic, age-related changes in brain…

计算机视觉与模式识别 · 计算机科学 2026-02-10 Yongheng Sun , Jun Shu , Jianhua Ma , Fan Wang

In-scanner motion degrades the quality of magnetic resonance imaging (MRI) thereby reducing its utility in the detection of clinically relevant abnormalities. We introduce a deep learning-based MRI artifact reduction model (DMAR) to…

图像与视频处理 · 电气工程与系统科学 2020-11-03 Yijun Zhao , Jacek Ossowski , Xuming Wang , Shangjin Li , Orrin Devinsky , Samantha P. Martin , Heath R. Pardoe

Single image super-resolution (SISR) aims to obtain a high-resolution output from one low-resolution image. Currently, deep learning-based SISR approaches have been widely discussed in medical image processing, because of their potential to…

图像与视频处理 · 电气工程与系统科学 2021-05-25 Jin Zhu , Chuan Tan , Junwei Yang , Guang Yang , Pietro Lio'

Diffusion magnetic resonance imaging (dMRI) plays a vital role in both clinical diagnostics and neuroscience research. However, its inherently low signal-to-noise ratio (SNR), especially under high diffusion weighting, significantly…

定量方法 · 定量生物学 2026-02-27 Jine Xie , Zhicheng Zhang , Yunwei Chen , Yanqiu Feng , Xinyuan Zhang

Artificial intelligence (AI) has introduced numerous opportunities for human assistance and task automation in medicine. However, it suffers from poor generalization in the presence of shifts in the data distribution. In the context of…

A common neurodegenerative disease, Alzheimer's disease requires a precise diagnosis and efficient treatment, particularly in light of escalating healthcare expenses and the expanding use of artificial intelligence in medical diagnostics.…

图像与视频处理 · 电气工程与系统科学 2025-05-21 Soyabul Islam Lincoln , Mirza Mohd Shahriar Maswood

We present a novel method that allows for measuring the quality of diffusion-weighted MR images dependent on the image resolution and the image noise. For this purpose, we introduce a new thresholding technique so that noise and the signal…

计算机视觉与模式识别 · 计算机科学 2011-05-10 Jan Klein , Sebastiano Barbieri , Miriam H. A. Bauer , Christopher Nimsky , Horst K. Hahn