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Multimodal Large Language Models (MLLMs) have shown significant potential in surgical video understanding. With improved zero-shot performance and more effective human-machine interaction, they provide a strong foundation for advancing…

计算机视觉与模式识别 · 计算机科学 2025-12-09 Ziyang Song , Zelin Zang , Xiaofan Ye , Boqiang Xu , Long Bai , Jinlin Wu , Hongliang Ren , Hongbin Liu , Jiebo Luo , Zhen Lei

Antibodies play a central role in the immune response by specifically recognizing and neutralizing antigens, and therapeutic antibodies have become major drugs for cancer and autoimmune diseases. However, their discovery still relies on…

定量方法 · 定量生物学 2026-05-29 Xiao Luo

Effective processing, interpretation, and management of sensor data have emerged as a critical component of cyber-physical systems. Traditionally, processing sensor data requires profound theoretical knowledge and proficiency in…

人工智能 · 计算机科学 2025-04-01 Pengrui Quan , Xiaomin Ouyang , Jeya Vikranth Jeyakumar , Ziqi Wang , Yang Xing , Mani Srivastava

Large Language Models (LLMs) remain difficult to evaluate comprehensively, particularly for languages other than English, where high-quality data is often limited. Existing benchmarks and leaderboards are predominantly English-centric, with…

Pretraining DNA language models (DNALMs) on the full human genome is resource-intensive, yet often considered necessary for strong downstream performance. Inspired by recent findings in NLP and long-context modeling, we explore an…

基因组学 · 定量生物学 2025-06-24 Sohan Mupparapu , Parameswari Krishnamurthy , Ratish Puduppully

Tandem mass spectrometry provides a high-throughput framework for identifying and quantifying proteins in complex biological samples. In computational proteomics, predicting peptide MS/MS spectra is a critical task, enabling downstream…

机器学习 · 计算机科学 2026-05-05 Zhiwen Yang , Pan Liu , Yifan Li , Yunhua Zhong , Jun Xia

Large language models (LLMs) have become important tools in solving biological problems, offering improvements in accuracy and adaptability over conventional methods. Several benchmarks have been proposed to evaluate the performance of…

Recent advances in large language models (LLMs) and medical LLMs (Med-LLMs) have demonstrated strong performance on general medical benchmarks. However, their capabilities in specialized medical fields, such as dentistry which require…

计算与语言 · 计算机科学 2025-08-29 Hengchuan Zhu , Yihuan Xu , Yichen Li , Zijie Meng , Zuozhu Liu

Foundation models have established unified representations for natural language processing, yet this paradigm remains largely unexplored for tabular data. Existing methods face fundamental limitations: LLM-based approaches lack…

计算与语言 · 计算机科学 2026-05-07 Minjie Qiang , Mingming Zhang , Xiaoyi Bao , Xing Fu , Yu Cheng , Weiqiang Wang , Zhongqing Wang , Ningtao Wang

Recently, Large Language Models (LLM) have demonstrated impressive capability to solve a wide range of tasks. However, despite their success across various tasks, no prior work has investigated their capability in the biomedical domain yet.…

计算与语言 · 计算机科学 2024-02-21 Israt Jahan , Md Tahmid Rahman Laskar , Chun Peng , Jimmy Huang

There is widespread optimism that frontier Large Language Models (LLMs) and LLM-augmented systems have the potential to rapidly accelerate scientific discovery across disciplines. Today, many benchmarks exist to measure LLM knowledge and…

Endoscopic procedures are essential for diagnosing and treating internal diseases, and multi-modal large language models (MLLMs) are increasingly applied to assist in endoscopy analysis. However, current benchmarks are limited, as they…

计算机视觉与模式识别 · 计算机科学 2025-09-25 Shengyuan Liu , Boyun Zheng , Wenting Chen , Zhihao Peng , Zhenfei Yin , Jing Shao , Jiancong Hu , Yixuan Yuan

For protein sequence datasets, unlabeled data has greatly outpaced labeled data due to the high cost of wet-lab characterization. Recent deep-learning approaches to protein prediction have shown that pre-training on unlabeled data can yield…

机器学习 · 计算机科学 2020-12-02 Pascal Sturmfels , Jesse Vig , Ali Madani , Nazneen Fatema Rajani

Benchmarks are the de facto standard for tracking progress in large language models (LLMs), yet static test sets can rapidly saturate, become vulnerable to contamination, and are costly to refresh. Scalable evaluation of open-ended items…

计算与语言 · 计算机科学 2026-03-24 Yandan Zheng , Haoran Luo , Zhenghong Lin , Wenjin Liu , Luu Anh Tuan

NL2VIS - which translates natural language (NL) queries to corresponding visualizations (VIS) - has attracted more and more attention both in commercial visualization vendors and academic researchers. In the last few years, the advanced…

人机交互 · 计算机科学 2021-12-28 Yuyu Luo , Jiawei Tang , Guoliang Li

Recent years have witnessed a surge in the development of protein foundation models, significantly improving performance in protein prediction and generative tasks ranging from 3D structure prediction and protein design to conformational…

定量方法 · 定量生物学 2024-10-08 Fei Ye , Zaixiang Zheng , Dongyu Xue , Yuning Shen , Lihao Wang , Yiming Ma , Yan Wang , Xinyou Wang , Xiangxin Zhou , Quanquan Gu

Multimodal Large Language Models (LLMs) hold promise for biomedical reasoning, but current benchmarks fail to capture the complexity of real-world clinical workflows. Existing evaluations primarily assess unimodal, decontextualized…

Recent developments in large language models (LLMs) have shown promise in enhancing the capabilities of natural language processing (NLP). Despite these successes, there remains a dearth of research dedicated to the NLP problem-solving…

计算与语言 · 计算机科学 2023-10-20 Linxin Song , Jieyu Zhang , Lechao Cheng , Pengyuan Zhou , Tianyi Zhou , Irene Li

Most of the existing Large Language Model (LLM) benchmarks on scientific problem reasoning focus on problems grounded in high-school subjects and are confined to elementary algebraic operations. To systematically examine the reasoning…

Function-guided protein design is a crucial task with significant applications in drug discovery and enzyme engineering. However, the field lacks a unified and comprehensive evaluation framework. Current models are assessed using…

机器学习 · 计算机科学 2025-09-30 Jiahao Kuang , Nuowei Liu , Jie Wang , Changzhi Sun , Tao Ji , Yuanbin Wu