中文
相关论文

相关论文: Stabilizing Reasoning in Medical LLMs with Continu…

200 篇论文

This study evaluates causal reasoning in large language models (LLMs) using 99 clinically grounded laboratory test scenarios aligned with Pearl's Ladder of Causation: association, intervention, and counterfactual reasoning. We examined…

人工智能 · 计算机科学 2025-09-23 Balu Bhasuran , Mattia Prosperi , Karim Hanna , John Petrilli , Caretia JeLayne Washington , Zhe He

Large Language Models (LLMs) are primarily trained on high-resource natural languages, limiting their effectiveness in low-resource settings and in tasks requiring deep logical reasoning. This research introduces Rosetta-PL, a benchmark…

Large language models (LLMs) demonstrate strong multilingual capabilities, yet often fail to consistently generate responses in the intended language, exhibiting a phenomenon known as language confusion. Prior mitigation approaches based on…

计算与语言 · 计算机科学 2026-04-30 Jinho Choo , JunSeung Lee , Jimyeong Kim , Yeeho Song , S. K. Hong , Yeong-Dae Kwon

This paper identifies a critical yet underexplored challenge in reasoning alignment from multiple multi-modal large language models (MLLMs): In non-stationary environments, the diverse reasoning distributions of source models often evolve…

计算机视觉与模式识别 · 计算机科学 2026-05-12 Xiaoyu Yang , En Yu , Wei Duan , Jie Lu

Large language models (LLMs) often lack specialized knowledge for complex bioinformatics applications. We present a reproducible pipeline for fine-tuning LLMs on specialized bioinformatics data, demonstrated through two use cases: PRSGPT,…

计算与语言 · 计算机科学 2026-01-21 Muhammad Muneeb , David B. Ascher

Large language models (LLMs) increasingly solve difficult problems by producing "reasoning traces" before emitting a final response. However, it remains unclear how accuracy and decision commitment evolve along a reasoning trajectory, and…

机器学习 · 计算机科学 2026-02-02 Marthe Ballon , Brecht Verbeken , Vincent Ginis , Andres Algaba

Phenotype-driven gene prioritization is a critical process in the diagnosis of rare genetic disorders for identifying and ranking potential disease-causing genes based on observed physical traits or phenotypes. While traditional approaches…

定量方法 · 定量生物学 2024-04-04 Junyoung Kim , Jingye Yang , Kai Wang , Chunhua Weng , Cong Liu

In the ongoing wave of impact driven by large language models (LLMs) like ChatGPT, the adaptation of LLMs to medical domain has emerged as a crucial research frontier. Since mainstream LLMs tend to be designed for general-purpose…

计算与语言 · 计算机科学 2023-12-04 Issey Sukeda , Masahiro Suzuki , Hiroki Sakaji , Satoshi Kodera

Accurate and consistent Emergency Severity Index (ESI) assignment remains a persistent challenge in emergency departments, where highly variable free-text triage documentation contributes to mistriage and workflow inefficiencies. This study…

计算与语言 · 计算机科学 2026-04-30 Manar Aljohani , Brandon Ho , Kenneth McKinley , Dennis Ren , Xuan Wang

Despite the efficacy of Direct Preference Optimization (DPO) in aligning Large Language Models (LLMs), reward hacking remains a pivotal challenge. This issue emerges when LLMs excessively reduce the probability of rejected completions to…

计算与语言 · 计算机科学 2025-08-26 Chenxu Yang , Ruipeng Jia , Mingyu Zheng , Naibin Gu , Zheng Lin , Siyuan Chen , Weichong Yin , Hua Wu , Weiping Wang

LLMs are revolutionizing NLP tasks. However, the use of the most advanced LLMs, such as GPT-4, is often prohibitively expensive for most specialized fields. We introduce HEAL, the first continuously trained 13B LLaMA2-based LLM that is…

计算与语言 · 计算机科学 2024-04-05 Dong Yuan , Eti Rastogi , Gautam Naik , Sree Prasanna Rajagopal , Sagar Goyal , Fen Zhao , Bharath Chintagunta , Jeff Ward

Recently, preference optimization methods such as DPO have significantly enhanced large language models (LLMs) in wide tasks including dialogue and question-answering. However, current methods fail to account for the varying difficulty…

计算与语言 · 计算机科学 2024-12-31 Jingyuan Ma , Rui Li , Zheng Li , Lei Sha , Zhifang Sui

Large Language Models (LLMs) are increasingly adopted as evaluators, offering a scalable alternative to human annotation. However, existing supervised fine-tuning (SFT) approaches often fall short in domains that demand complex reasoning.…

计算与语言 · 计算机科学 2025-11-04 Nuo Chen , Zhiyuan Hu , Qingyun Zou , Jiaying Wu , Qian Wang , Bryan Hooi , Bingsheng He

In this report, we introduce PLaMo 2, a series of Japanese-focused large language models featuring a hybrid Samba-based architecture that transitions to full attention via continual pre-training to support 32K token contexts. Training…

Process-Level Reward Models (PRMs) are essential for guiding complex reasoning in large language models, yet existing PRM benchmarks cover only general domains such as mathematics, failing to address medical reasoning -- which is uniquely…

计算与语言 · 计算机科学 2026-04-21 Lingyan Wu , Xiang Zheng , Weiqi Zhai , Wei Wang , Xuan Ren , Zifan Zhang , Hu Wei , Bing Zhao

General-purpose large language models (LLMs) have demonstrated remarkable generative and reasoning capabilities but remain limited in healthcare and caregiving applications due to two key deficiencies: factual unreliability and a lack of…

计算与语言 · 计算机科学 2025-12-09 Emre Umucu , Guillermina Solis , Leon Garza , Emilia Rivas , Beatrice Lee , Anantaa Kotal , Aritran Piplai

In the field of large language models (LLMs), aligning models with the diverse preferences of users is a critical challenge. Direct Preference Optimization (DPO) has played a key role in this area. It works by using pairs of preferences…

计算与语言 · 计算机科学 2024-05-29 Yueqin Yin , Zhendong Wang , Yi Gu , Hai Huang , Weizhu Chen , Mingyuan Zhou

While astonishingly capable, large Language Models (LLM) can sometimes produce outputs that deviate from human expectations. Such deviations necessitate an alignment phase to prevent disseminating untruthful, toxic, or biased information.…

人工智能 · 计算机科学 2024-10-30 Long Tan Le , Han Shu , Tung-Anh Nguyen , Choong Seon Hong , Nguyen H. Tran

The surprising ability of Large Language Models (LLMs) to perform well on complex reasoning with only few-shot chain-of-thought prompts is believed to emerge only in very large-scale models (100+ billion parameters). We show that such…

计算与语言 · 计算机科学 2023-01-31 Yao Fu , Hao Peng , Litu Ou , Ashish Sabharwal , Tushar Khot

Clinical reasoning in medicine is a hypothesis-driven process where physicians refine diagnoses from limited information through targeted history, physical examination, and diagnostic investigations. In contrast, current medical benchmarks…

机器学习 · 计算机科学 2025-10-14 Christopher Chiu , Silviu Pitis , Mihaela van der Schaar