相关论文: GeneMamba: An Efficient and Effective Foundation M…

Recently, the state space model (SSM) represented by Mamba has shown remarkable performance in long-term sequence modeling tasks, including speech enhancement. However, due to substantial differences in sub-band features, applying the same…

Large pre-trained models have achieved outstanding results in sequence modeling. The Transformer block and its attention mechanism have been the main drivers of the success of these models. Recently, alternative architectures, such as…

Single-cell RNA sequencing (scRNA-seq) enables dissecting cellular heterogeneity in tissues, resulting in numerous biological discoveries. Various computational methods have been devised to delineate cell types by clustering scRNA-seq data…

Single-cell RNA sequencing (scRNA-seq), especially temporally resolved datasets, enables genome-wide profiling of gene expression dynamics at single-cell resolution across discrete time points. However, current technologies provide only…

Survival analysis using whole-slide images (WSIs) is crucial in cancer research. Despite significant successes, pathology images typically only provide slide-level labels, which hinders the learning of discriminative representations from…

In clinical practice, medical image segmentation provides useful information on the contours and dimensions of target organs or tissues, facilitating improved diagnosis, analysis, and treatment. In the past few years, convolutional neural…

Recent works have shown the remarkable superiority of transformer models in reinforcement learning (RL), where the decision-making problem is formulated as sequential generation. Transformer-based agents could emerge with self-improvement…

Diffusion models have achieved great success in image generation, with the backbone evolving from U-Net to Vision Transformers. However, the computational cost of Transformers is quadratic to the number of tokens, leading to significant…

We introduce VideoMamba, a novel adaptation of the pure Mamba architecture, specifically designed for video recognition. Unlike transformers that rely on self-attention mechanisms leading to high computational costs by quadratic complexity,…

Deep learning, particularly convolutional neural networks (CNNs) and Transformers, has significantly advanced 3D medical image segmentation. While CNNs are highly effective at capturing local features, their limited receptive fields may…

We introduce Llamba, a family of efficient recurrent language models distilled from Llama-3.x into the Mamba architecture. The series includes Llamba-1B, Llamba-3B, and Llamba-8B, which achieve higher inference throughput and handle…

An ecosystem of Transformer-based models has been established by building large models with extensive data. Parameter-efficient fine-tuning (PEFT) is a crucial technology for deploying these models to downstream tasks with minimal cost…

Single-Cell RNA sequencing (scRNA-seq) measurements have facilitated genome-scale transcriptomic profiling of individual cells, with the hope of deconvolving cellular dynamic changes in corresponding cell sub-populations to better…

In recent years, deep learning has shown near-expert performance in segmenting complex medical tissues and tumors. However, existing models are often task-specific, with performance varying across modalities and anatomical regions.…

Single-cell RNA sequencing (scRNA-seq) is powerful technology that allows researchers to understand gene expression patterns at the single-cell level. However, analysing scRNA-seq data is challenging due to issues and biases in data…

Recent years have witnessed significant advancements in light field image super-resolution (LFSR) owing to the progress of modern neural networks. However, these methods often face challenges in capturing long-range dependencies (CNN-based)…

We propose ss-Mamba, a novel foundation model that enhances time series forecasting by integrating semantic-aware embeddings and adaptive spline-based temporal encoding within a selective state-space modeling framework. Building upon the…

Recent advancements in State Space Models, notably Mamba, have demonstrated superior performance over the dominant Transformer models, particularly in reducing the computational complexity from quadratic to linear. Yet, difficulties in…

As the primary mRNA delivery vehicles, ionizable lipid nanoparticles (LNPs) exhibit excellent safety, high transfection efficiency, and strong immune response induction. However, the screening process for LNPs is time-consuming and costly.…

The integration of single-cell proteomic data is often hindered by the fragmented nature of targeted antibody panels. To address this limitation, we introduce scpFormer, a transformer-based foundation model designed for single-cell…