相关论文: Teaching pathology foundation models to accurately…

Parameter-efficient fine-tuning (PEFT) is a highly effective approach for adapting large pre-trained models to downstream tasks with minimal computational overhead. At the core, PEFT methods freeze most parameters and only trains a small…

Predicting spatial gene expression from routine H\&E enables large-scale molecular profiling, yet current models treat this as isolated pointwise tasks, thereby overlooking essential biological structures like gene coordination and spatial…

Predicting pedestrian motion trajectories is crucial for path planning and motion control of autonomous vehicles. Accurately forecasting crowd trajectories is challenging due to the uncertain nature of human motions in different…

Deep learning-based nuclei segmentation and classification in pathology images typically rely on large-scale pixel-level manual annotations, which are costly and difficult to obtain across diverse tissues and staining conditions. To address…

Medical image segmentation is crucial for disease diagnosis and treatment planning, yet developing robust segmentation models often requires substantial computational resources and large datasets. Existing research shows that pre-trained…

When modeling multivariate data, one might have an extra parameter of contextual information that could be used to treat some observations as more similar to others. For example, images of faces can vary by age, and one would expect the…

Domain generalization (DG) aims to avoid the performance degradation of the model when the distribution shift between the limited training data and unseen test data occurs. Recently, foundation models with enormous parameters have been…

Data profiling has garnered increasing attention within the data science community, primarily focusing on structured data. In this paper, we introduce a novel framework called panacea, designed to profile known cancer target combinations in…

Large protein language models are adept at capturing the underlying evolutionary information in primary structures, offering significant practical value for protein engineering. Compared to natural language models, protein amino acid…

With the growing interest in foundation models for brain signals, graph-based pretraining has emerged as a promising paradigm for learning transferable representations from connectome data. However, existing contrastive and masked…

Recent years, transfer learning has attracted much attention in the community of machine learning. In this paper, we mainly focus on the tasks of parameter transfer under the framework of extreme learning machine (ELM). Unlike the existing…

Diabetes is a worldwide health issue affecting millions of people. Machine learning methods have shown promising results in improving diabetes prediction, particularly through the analysis of diverse data types, namely gene expression data.…

With the rapid development of computational pathology, many AI-assisted diagnostic tasks have emerged. Cellular nuclei segmentation can segment various types of cells for downstream analysis, but it relies on predefined categories and lacks…

Principal Component Analysis (PCA) is a powerful and popular dimensionality reduction technique. However, due to its linear nature, it often fails to capture the complex underlying structure of real-world data. While Kernel PCA (kPCA)…

The study of cellular signalling pathways and their deregulation in disease states, such as cancer, is a large and extremely complex task. Indeed, these systems involve many parts and processes but are studied piecewise and their…

Representation alignment (REPA) guides generative training by distilling representations from a strong, pretrained vision encoder to intermediate diffusion features. We investigate a fundamental question: what aspect of the target…

The recent popularity of foundation models and the pre-train-and-adapt paradigm, where a large-scale model is transferred to downstream tasks, is gaining attention for volumetric medical image segmentation. However, current transfer…

Cancer diagnosis, prognosis, and therapeutic response predictions are based on morphological information from histology slides and molecular profiles from genomic data. However, most deep learning-based objective outcome prediction and…

Molecular property prediction is essential for drug discovery. In recent years, deep learning methods have been introduced to this area and achieved state-of-the-art performances. However, most of existing methods ignore the intrinsic…

Accurate recognition of human emotional states is critical for effective human-machine interaction. Electroencephalography (EEG) offers a reliable source for emotion recognition due to its high temporal resolution and its direct reflection…