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Traditional RLHF-based LLM alignment methods explicitly maximize the expected rewards from a separate reward model. More recent supervised alignment methods like Direct Preference Optimization (DPO) circumvent this phase to avoid problems…

机器学习 · 计算机科学 2025-02-03 Abhijnan Nath , Changsoo Jung , Ethan Seefried , Nikhil Krishnaswamy

Multimodal Large Language Models (MLLMs) have significantly improved the performance of various tasks, but continue to suffer from visual hallucinations, a critical issue where generated responses contradict visual evidence. While Direct…

计算机视觉与模式识别 · 计算机科学 2025-09-30 Yuanshuai Li , Yuping Yan , Junfeng Tang , Yunxuan Li , Zeqi Zheng , Yaochu Jin

A major challenge in aligning large language models (LLMs) with human preferences is the issue of distribution shift. LLM alignment algorithms rely on static preference datasets, assuming that they accurately represent real-world user…

机器学习 · 计算机科学 2026-01-16 Zaiyan Xu , Sushil Vemuri , Kishan Panaganti , Dileep Kalathil , Rahul Jain , Deepak Ramachandran

We study inventory control policies for pharmaceutical supply chains, addressing challenges such as perishability, yield uncertainty, and non-stationary demand, combined with batching constraints, lead times, and lost sales. Collaborating…

人工智能 · 计算机科学 2025-01-22 Francesco Stranieri , Chaaben Kouki , Willem van Jaarsveld , Fabio Stella

Generating visually appealing images is fundamental to modern text-to-image generation models. A potential solution to better aesthetics is direct preference optimization (DPO), which has been applied to diffusion models to improve general…

计算机视觉与模式识别 · 计算机科学 2025-03-26 Zhanhao Liang , Yuhui Yuan , Shuyang Gu , Bohan Chen , Tiankai Hang , Mingxi Cheng , Ji Li , Liang Zheng

With the rapid advancement of large language models (LLMs), aligning policy models with human preferences has become increasingly critical. Direct Preference Optimization (DPO) has emerged as a promising approach for alignment, acting as an…

人工智能 · 计算机科学 2025-07-15 Wenyi Xiao , Zechuan Wang , Leilei Gan , Shuai Zhao , Zongrui Li , Ruirui Lei , Wanggui He , Luu Anh Tuan , Long Chen , Hao Jiang , Zhou Zhao , Fei Wu

Direct Preference Optimization (DPO) has emerged as a cornerstone of reinforcement learning from human feedback (RLHF) due to its simplicity and efficiency. However, existing DPO-based methods typically treat all preference pairs equally,…

Recent advancements in Direct Preference Optimization (DPO) have significantly enhanced the alignment of Large Language Models (LLMs) with human preferences, owing to its simplicity and effectiveness. However, existing methods typically…

计算与语言 · 计算机科学 2024-10-28 Shilong Li , Yancheng He , Hui Huang , Xingyuan Bu , Jiaheng Liu , Hangyu Guo , Weixun Wang , Jihao Gu , Wenbo Su , Bo Zheng

Large Language Models (LLMs) as autonomous agents are increasingly tasked with solving complex, long-horizon problems. Aligning these agents via preference-based offline methods like Direct Preference Optimization (DPO) is a promising…

机器学习 · 计算机科学 2026-03-03 Heyang Gao , Zexu Sun , Erxue Min , Hengyi Cai , Shuaiqiang Wang , Dawei Yin , Xu Chen

Recent developments in Direct Preference Optimization (DPO) allow large language models (LLMs) to function as implicit ranking models by maximizing the margin between preferred and non-preferred responses. In practice, user feedback on such…

Recommender systems aim to predict personalized rankings based on user preference data. With the rise of Language Models (LMs), LM-based recommenders have been widely explored due to their extensive world knowledge and powerful reasoning…

信息检索 · 计算机科学 2024-11-08 Yuxin Chen , Junfei Tan , An Zhang , Zhengyi Yang , Leheng Sheng , Enzhi Zhang , Xiang Wang , Tat-Seng Chua

We introduce Direct Value Optimization (DVO), an innovative reinforcement learning framework for enhancing large language models in complex reasoning tasks. Unlike traditional methods relying on preference labels, DVO utilizes value signals…

计算与语言 · 计算机科学 2025-02-20 Hongbo Zhang , Han Cui , Guangsheng Bao , Linyi Yang , Jun Wang , Yue Zhang

In the field of Structure-based Drug Design (SBDD), deep learning-based generative models have achieved outstanding performance in terms of docking score. However, further study shows that the existing molecular generative methods and…

生物大分子 · 定量生物学 2024-03-21 Bowen Gao , Minsi Ren , Yuyan Ni , Yanwen Huang , Bo Qiang , Zhi-Ming Ma , Wei-Ying Ma , Yanyan Lan

Diffusion policies, widely adopted in decision-making scenarios such as robotics, gaming and autonomous driving, are capable of learning diverse skills from demonstration data due to their high representation power. However, the sub-optimal…

机器学习 · 计算机科学 2025-09-30 Ningyuan Yang , Jiaxuan Gao , Feng Gao , Yi Wu , Chao Yu

Direct Preference Optimization (DPO) has been proposed as a promising alternative to Proximal Policy Optimization (PPO) based Reinforcement Learning with Human Feedback (RLHF). However, empirical evaluations consistently reveal suboptimal…

机器学习 · 计算机科学 2025-03-03 Qinwei Ma , Jingzhe Shi , Can Jin , Jenq-Neng Hwang , Serge Belongie , Lei Li

This work introduces a method to tune a sequence-based generative model for molecular de novo design that through augmented episodic likelihood can learn to generate structures with certain specified desirable properties. We demonstrate how…

人工智能 · 计算机科学 2017-08-30 Marcus Olivecrona , Thomas Blaschke , Ola Engkvist , Hongming Chen

Group Relative Policy Optimization(GRPO) has become a cornerstone of modern reinforcement learning alignment, prized for its efficacy in foregoing an explicit value-critic by leveraging reward normalization across sampled trajectory…

计算与语言 · 计算机科学 2026-05-29 Redacted by arXiv

The ultimate goal of drug design is to find novel compounds with desirable pharmacological properties. Designing molecules retaining particular scaffolds as the core structures of the molecules is one of the efficient ways to obtain…

定量方法 · 定量生物学 2019-09-06 Yibo Li , Jianxing Hu , Yanxing Wang , Jielong Zhou , Liangren Zhang , Zhenming Liu

Direct Preference Optimization (DPO) has become a prominent method for aligning Large Language Models (LLMs) with human preferences. While DPO has enabled significant progress in aligning English LLMs, multilingual preference alignment is…

计算与语言 · 计算机科学 2025-06-06 Wen Yang , Junhong Wu , Chen Wang , Chengqing Zong , Jiajun Zhang

Recent deep reinforcement learning methods have achieved remarkable success in solving multi-objective combinatorial optimization problems (MOCOPs) by decomposing them into multiple subproblems, each associated with a specific weight…

人工智能 · 计算机科学 2026-03-23 Mingfeng Fan , Jianan Zhou , Yifeng Zhang , Yaoxin Wu , Jinbiao Chen , Guillaume Adrien Sartoretti
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