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Stereotactic radiotherapy (SRT) is one of the most important treatment for patients with brain metastases (BM). Conventionally, following SRT patients are monitored by serial imaging and receive salvage treatments in case of significant…

计算机视觉与模式识别 · 计算机科学 2023-02-20 Philipp Sommer , Yixing Huang , Christoph Bert , Andreas Maier , Manuel Schmidt , Arnd Dörfler , Rainer Fietkau , Florian Putz

Brain Metastases (BM) are a large contributor to mortality of patients with cancer. They are treated with Stereotactic Radiosurgery (SRS) and monitored with Magnetic Resonance Imaging (MRI) at regular follow-up intervals according to…

In MR fingerprinting (MRF) reconstruction, measured data is pattern-matched to simulated signals to extract quantitative tissue parameters. A critical drawback to this approach is the exponentially increasing compute time for mapping of…

医学物理 · 物理学 2024-07-17 Victoria Y. Yu , Kathryn R. Tringale , Ricardo Otazo , Ouri Cohen

Brain metastases are a common diagnosis that affects between 20% and 40% of cancer patients. Subsequent to radiation therapy, patients with brain metastases undergo follow-up sessions during which the response to treatment is monitored. In…

图像与视频处理 · 电气工程与系统科学 2024-12-24 Margarida Fernandes , José Soares , Matheus Silva , Crystian Saraiva , Victor Alves

Magnetic Resonance Imaging (MRI) plays a crucial role in MRI-guided adaptive radiotherapy for head and neck cancer (HNC) due to its superior soft-tissue contrast. However, accurately segmenting the gross tumor volume (GTV), which includes…

计算机视觉与模式识别 · 计算机科学 2024-10-18 Jintao Ren , Kim Hochreuter , Jesper Folsted Kallehauge , Stine Sofia Korreman

Stereotactic radiosurgery is a minimally-invasive treatment option for a large number of patients with intracranial tumors. As part of the therapy treatment, accurate delineation of brain tumors is of great importance. However,…

Background: This study aimed to predict lesion-specific outcomes after stereotactic radiotherapy (SRT) in patients with brain metastases from malignant melanoma (MBM), using clinical, dosimetric, and pretherapeutic MRI data. Methods: In…

Magnetic Resonance Imaging (MRI) is increasingly incorporated into treatment planning, because of its superior soft tissue contrast used for tumor and soft tissue delineation versus computed tomography (CT). However, MRI cannot directly…

Personalized ultra-fractionated stereotactic adaptive radiotherapy (PULSAR) is a novel treatment that delivers radiation in pulses of protracted intervals. Accurate prediction of gross tumor volume (GTV) changes through regression models…

机器学习 · 计算机科学 2025-09-18 Yajun Yu , Steve Jiang , Robert Timmerman , Hao Peng

Detecting and segmenting brain metastases is a tedious and time-consuming task for many radiologists, particularly with the growing use of multi-sequence 3D imaging. This study demonstrates automated detection and segmentation of brain…

图像与视频处理 · 电气工程与系统科学 2019-12-30 Endre Grøvik , Darvin Yi , Michael Iv , Elisabeth Tong , Daniel L. Rubin , Greg Zaharchuk

Brain metastases affect approximately between 20% and 40% of cancer patients and are commonly treated with radiotherapy or radiosurgery. Early prediction of recurrence following treatment could enable timely clinical intervention and…

图像与视频处理 · 电气工程与系统科学 2025-12-18 Ines Faria , Matheus Silva , Crystian Saraiva , Jose Soares , Victor Alves

Purpose: This study demonstrated an MR signal multitask learning method for 3D simultaneous segmentation and relaxometry of human brain tissues. Materials and Methods: A 3D inversion-prepared balanced steady-state free precession sequence…

医学物理 · 物理学 2019-12-02 Peng Cao , Jing Liu , Shuyu Tang , Andrew Leynes , Janine M. Lupo , Duan Xu , Peder E. Z. Larson

Brain metastases are a complication of primary cancer, representing the most common type of brain tumor in adults. The management of multiple brain metastases represents a clinical challenge worldwide in finding the optimal treatment for…

图像与视频处理 · 电气工程与系统科学 2024-03-28 Ana Sofia Santos , Matheus Silva , Crystian Saraiva , José Soares , Victor Alves

Introduction: Lung cancer is a leading cause of cancer-related mortality, and stereotactic body radiotherapy (SBRT) has become a standard treatment for early-stage lung cancer. However, the heterogeneous response to radiation at the tumor…

Purpose: To evaluate the clinical need for automated decision-support platforms for Adaptive Radiotherapy Therapy (ART) of Head & Neck cancer (HNC) patients. Methods: We tested RTapp (SegAna), a new decision-support software for ART, to…

医学物理 · 物理学 2021-10-05 Sébastien A A Gros , Anand P Santhanam , Alec M Block , Bahman Emami , Brian H Lee , Cara Joyce

Stereotactic radiosurgery (SRS), which delivers high doses of irradiation in a single or few shots to small targets, has been a standard of care for brain metastases. While very effective, SRS currently requires manually intensive…

图像与视频处理 · 电气工程与系统科学 2019-08-16 Szu-Yeu Hu , Wei-Hung Weng , Shao-Lun Lu , Yueh-Hung Cheng , Furen Xiao , Feng-Ming Hsu , Jen-Tang Lu

Brain tumors are serious health problems that require early diagnosis due to their high mortality rates. Diagnosing tumors by examining Magnetic Resonance Imaging (MRI) images is a process that requires expertise and is prone to error.…

计算机视觉与模式识别 · 计算机科学 2026-04-10 Mustafa Yurdakul , Şakir Taşdemir

Accurate evaluation of the response of glioblastoma to therapy is crucial for clinical decision-making and patient management. The Response Assessment in Neuro-Oncology (RANO) criteria provide a standardized framework to assess patients'…

计算机视觉与模式识别 · 计算机科学 2025-09-09 Daniil Tikhonov , Matheus Scatolin , Mohor Banerjee , Qiankun Ji , Ahmed Jaheen , Mostafa Salem , Abdelrahman Elsayed , Hu Wang , Sarim Hashmi , Mohammad Yaqub

Automatic brain tumor segmentation from Magnetic Resonance Imaging (MRI) data plays an important role in assessing tumor response to therapy and personalized treatment stratification.Manual segmentation is tedious and…

图像与视频处理 · 电气工程与系统科学 2021-11-29 Hadas Ben-Atya , Ori Rajchert , Liran Goshen , Moti Freiman

Purpose: We aimed to develop a data-driven multiomics approach integrating radiomics, dosiomics, and delta features to predict treatment response at an earlier stage (intra-treatment) for brain metastases (BMs) patients treated with PULSAR.…

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