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The Vision Foundation Model has recently gained attention in medical image analysis. Its zero-shot learning capabilities accelerate AI deployment and enhance the generalizability of clinical applications. However, segmenting pathological…

计算机视觉与模式识别 · 计算机科学 2024-07-16 Can Cui , Ruining Deng , Junlin Guo , Quan Liu , Tianyuan Yao , Haichun Yang , Yuankai Huo

Scaling up model and data size have demonstrated impressive performance improvement over a wide range of tasks. Despite extensive studies on scaling behaviors for general-purpose tasks, medical images exhibit substantial differences from…

计算机视觉与模式识别 · 计算机科学 2025-05-15 Jiarun Liu , Hong-Yu Zhou , Weijian Huang , Hao Yang , Dongning Song , Tao Tan , Yong Liang , Shanshan Wang

Neural networks achieve state-of-the-art performance in many supervised learning tasks when the training data distribution matches the test data distribution. However, their performance drops significantly under domain (covariate) shift, a…

计算机视觉与模式识别 · 计算机科学 2024-09-13 Kerem Cekmeceli , Meva Himmetoglu , Guney I. Tombak , Anna Susmelj , Ertunc Erdil , Ender Konukoglu

Data augmentation is an effective and universal technique for improving generalization performance of deep neural networks. It could enrich diversity of training samples that is essential in medical image segmentation tasks because 1) the…

图像与视频处理 · 电气工程与系统科学 2020-12-29 Ju Xu , Mengzhang Li , Zhanxing Zhu

Fundus diseases are major causes of visual impairment and blindness worldwide, especially in underdeveloped regions, where the shortage of ophthalmologists hinders timely diagnosis. AI-assisted fundus image analysis has several advantages,…

The automatic diagnosis of various retinal diseases from fundus images is important to support clinical decision-making. However, developing such automatic solutions is challenging due to the requirement of a large amount of human-annotated…

计算机视觉与模式识别 · 计算机科学 2020-07-23 Xiaomeng Li , Mengyu Jia , Md Tauhidul Islam , Lequan Yu , Lei Xing

The field of computational pathology has been transformed with recent advances in foundation models that encode histopathology region-of-interests (ROIs) into versatile and transferable feature representations via self-supervised learning…

Foundation models open up new possibilities for the use of AI in healthcare. However, even when pre-trained on health data, they still need to be fine-tuned for specific downstream tasks. Furthermore, although foundation models reduce the…

计算机视觉与模式识别 · 计算机科学 2025-10-15 Adam Tupper , Christian Gagné

Recent advances in deep learning have completely transformed the domain of computational pathology (CPath). More specifically, it has altered the diagnostic workflow of pathologists by integrating foundation models (FMs) and vision-language…

机器学习 · 计算机科学 2024-09-19 Dibaloke Chanda , Milan Aryal , Nasim Yahya Soltani , Masoud Ganji

Biological foundation models (BioFMs), pretrained on large-scale biological sequences, have recently shown strong potential in providing meaningful representations for diverse downstream bioinformatics tasks. However, such models often rely…

机器学习 · 计算机科学 2026-02-10 Yifan Wu , Jiyue Jiang , Xichen Ye , Yiqi Wang , Chang Zhou , Yitao Xu , Jiayang Chen , He Hu , Weizhong Zhang , Cheng Jin , Jiao Yuan , Yu Li

Computational pathology and whole-slide image (WSI) analysis are pivotal in cancer diagnosis and prognosis. However, the ultra-high resolution of WSIs presents significant modeling challenges. Recent advancements in pathology foundation…

计算机视觉与模式识别 · 计算机科学 2025-03-11 Honglin Li , Zhongyi Shui , Yunlong Zhang , Chenglu Zhu , Lin Yang

Whole slide images (WSI) are microscopy images of stained tissue slides routinely prepared for diagnosis and treatment selection in medical practice. WSI are very large (gigapixel size) and complex (made of up to millions of cells). The…

计算机视觉与模式识别 · 计算机科学 2022-12-08 Tristan Lazard , Marvin Lerousseau , Etienne Decencière , Thomas Walter

Foundational models (FMs), pretrained on extensive datasets using self-supervised techniques, are capable of learning generalized patterns from large amounts of data. This reduces the need for extensive labeled datasets for each new task,…

机器学习 · 计算机科学 2024-06-19 Quan M. Tran , Suong N. Hoang , Lam M. Nguyen , Dzung Phan , Hoang Thanh Lam

Labelling tissue components in histology whole slide images (WSIs) is prohibitively labour-intensive: a single slide may contain tens of thousands of structures--cells, nuclei, and other morphologically distinct objects--each requiring…

定量方法 · 定量生物学 2026-04-13 Muhammad Haseeb Ahmad , Sharmila Rajendran , Damion Young , Jon Mason

A crucial step to efficiently integrate Whole Slide Images (WSIs) in computational pathology is assigning a single high-quality feature vector, i.e., one embedding, to each WSI. With the existence of many pre-trained deep neural networks…

图像与视频处理 · 电气工程与系统科学 2025-05-22 Sobhan Hemati , Ghazal Alabtah , Saghir Alfasly , H. R. Tizhoosh

Histopathologists establish cancer grade by assessing histological structures, such as glands in prostate cancer. Yet, digital pathology pipelines often rely on grid-based tiling that ignores tissue architecture. This introduces irrelevant…

Current approaches for classification of whole slide images (WSI) in digital pathology predominantly utilize a two-stage learning pipeline. The first stage identifies areas of interest (e.g. tumor tissue), while the second stage processes…

计算机视觉与模式识别 · 计算机科学 2022-07-20 Marvin Teichmann , Andre Aichert , Hanibal Bohnenberger , Philipp Ströbel , Tobias Heimann

The development of medical vision-language foundation models has attracted significant attention in the field of medicine and healthcare due to their promising prospect in various clinical applications. While previous studies have commonly…

计算机视觉与模式识别 · 计算机科学 2024-02-27 Weijian Huang , Cheng Li , Hong-Yu Zhou , Jiarun Liu , Hao Yang , Yong Liang , Guangming Shi , Hairong Zheng , Shanshan Wang

Over the past decades, computer-aided diagnosis tools for breast cancer have been developed to enhance screening procedures, yet their clinical adoption remains challenged by data variability and inherent biases. Although foundation models…

计算机视觉与模式识别 · 计算机科学 2025-05-20 Elodie Germani , Ilayda Selin Türk , Fatima Zeineddine , Charbel Mourad , Shadi Albarqouni

In the realm of precision medicine, effective patient stratification and disease subtyping demand innovative methodologies tailored for multi-omics data. Clustering techniques applied to multi-omics data have become instrumental in…

机器学习 · 计算机科学 2024-01-30 Bastian Pfeifer , Christel Sirocchi , Marcus D. Bloice , Markus Kreuzthaler , Martin Urschler