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While diffusion models can learn complex distributions, sampling requires a computationally expensive iterative process. Existing distillation methods enable efficient sampling, but have notable limitations, such as performance degradation…

Naively, one expects the information communicated by an enzyme downstream within a signaling network, in which the enzyme is embedded, to grow monotonically with the enzyme's rate of product formation. However, here we observe that this…

生物物理 · 物理学 2020-07-01 Tushar Modi , S. Banu Ozkan , Steve Pressé

A Maxwell's demon is a device that gets information and trades it in for thermodynamic advantage, in apparent (but not actual) contradiction to the second law of thermodynamics. Quantum-mechanical versions of Maxwell's demon exhibit…

量子物理 · 物理学 2009-10-30 Seth Lloyd

The rate-limiting step of some enzymatic reactions is a physical step, i.e. diffusion. The efficiency of such reactions can be improved through an increase in the arrival rate of the substrate molecules, e.g. by a directed passage of…

生物物理 · 物理学 2007-05-23 Mehrdad Ghaemi , Nasrollah Rezaei-Ghaleh , Mohammad-Nabi Sarbolouki

Single enzyme chemotaxis is a phenomenon by which a non-equilibrium spatial distribution of an enzyme is created and maintained by concentration gradients of the substrate and product of the catalyzed reaction. These gradients can arise…

软凝聚态物质 · 物理学 2022-06-14 Niladri Sekhar Mandal , Ayusman Sen , R. Dean Astumian

The role of step edge diffusion (SED) in epitaxial growth is investigated. To this end we revisit and extend a recently introduced simple cubic solid-on-solid model, which exhibits the formation and coarsening of pyramid or mound like…

统计力学 · 物理学 2009-10-31 S. Schinzer , M. Kinne , M. Biehl , W. Kinzel

In solid-state electrochemical experiments, the boundary between the sample and the electrolyte plays a crucial role, and the rest of the sample acting as a buffer that maintains a fixed composition. Due to the presence of an…

材料科学 · 物理学 2023-10-24 Yakov I. Korepanov

The acid-mediated tumor invasion hypothesis proposes that altered glucose metabolism exhibited by the vast majority of tumors leads to increased acid (H+ ion) production which subsequently facilitates tumor invasion [1-3]. The…

组织与器官 · 定量生物学 2019-06-10 Ahmed M. Fouad

The long-standing paradigm of Maxwell's demon is till nowadays a frequently investigated issue, which still provides interesting insights into basic physical questions. Considering a single-electron transistor, where we implement a Maxwell…

量子物理 · 物理学 2018-02-08 G. Engelhardt , G. Schaller

We propose a new way of looking at the quantum Maxwell's demon problem in terms of conditional action. A "conditional action" on a system is a unitary time evolution, selected according to the result of a previous measurement, which can…

量子物理 · 物理学 2020-10-28 Heinz-Jürgen Schmidt

The cellular milieu is teeming with biochemical nano-machines whose activity is a strong source of correlated non-thermal fluctuations termed active noise. Essential elements of this circuitry are enzymes, catalysts that speed up the rate…

生物物理 · 物理学 2022-03-14 Ashwani Kr. Tripathi , Tamoghna Das , Govind Paneru , Hyuk Kyu Pak , Tsvi Tlusty

Electronic Energy Transfer (EET) between chromophores is fundamental in many natural light-harvesting complexes, serving as a critical step for solar energy funneling in photosynthetic plants and bacteria. The complicated role of the…

化学物理 · 物理学 2024-02-05 Colin Coane , Marco Romanelli , Giulia Dall'Osto , Rosa Di Felice , Stefano Corni

The diffusion of a molecular motor in the presence of a constant external force is considered on the basis of a simple theoretical model. The motor is represented by a Brownian particle moving in a series of parabolic potentials placed…

统计力学 · 物理学 2016-06-01 Ryota Shinagawa , Kazuo Sasaki

Generative models have shown strong generation ability while efficient likelihood estimation is less explored. Energy-based models~(EBMs) define a flexible energy function to parameterize unnormalized densities efficiently but are notorious…

机器学习 · 计算机科学 2024-06-11 Cong Geng , Tian Han , Peng-Tao Jiang , Hao Zhang , Jinwei Chen , Søren Hauberg , Bo Li

We use numerical simulations to examine two-dimensional particle mixtures that strongly phase separate in equilibrium. When the system is externally driven in the presence of quenched disorder, plastic flow occurs in the form of meandering…

统计力学 · 物理学 2009-11-13 A. Libal , C. Reichhardt , C. J. Olson Reichhardt

In the last twenty years there has been significant progress in our understanding of quantum transport far from equilibrium and a conceptual framework has emerged through a combination of the Landauer approach with the non-equilibrium Green…

介观与纳米尺度物理 · 物理学 2008-03-01 Supriyo Datta

It is demonstrated that Maxwell's demon can be used to allow a machine to extract energy from a heat bath by use of information that is processed by the demon at a remote location. The model proposed here effectively replaces transmission…

统计力学 · 物理学 2017-06-06 S. Hossenfelder

A spatio-temporal evolution of chemicals appearing in a reversible enzyme reaction and modelled by a four component reaction-diffusion system with the reaction terms obtained by the law of mass action is considered. The large time behaviour…

偏微分方程分析 · 数学 2016-10-25 Jan Elias

Parametric X-ray radiation (PXR) from relativistic electrons moving in a crystal along the crystal-vacuum interface is considered. In this geometry the emission of photons is happening in the regime of extremely asymmetric diffraction…

加速器物理 · 物理学 2017-09-25 O. D. Skoromnik , V. G. Baryshevsky , A. P. Ulyanenkov , I. D. Feranchuk

The problem of Maxwell's demon in granular gas is revisited in the case of a mixture of two particle species. The phase space is found to be 2d. Existence of cyclic orbits, with periodic segregation, is demonstrated by investigating the…

流体动力学 · 物理学 2011-11-24 P. Evesque