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Large language models (LLMs) have shown remarkable performance on many tasks in different domains. However, their performance in closed-book biomedical machine reading comprehension (MRC) has not been evaluated in depth. In this work, we…

计算与语言 · 计算机科学 2024-10-28 Shubham Vatsal , Ayush Singh

Large Language Models (LLMs) show potential for medical applications but often lack specialized clinical knowledge. Retrieval Augmented Generation (RAG) allows customization with domain-specific information, making it suitable for…

Retrieval-Augmented Generation (RAG) has been shown to enhance the factual accuracy of Large Language Models (LLMs), but existing methods often suffer from limited reasoning capabilities in effectively using the retrieved evidence,…

计算与语言 · 计算机科学 2024-10-03 Shayekh Bin Islam , Md Asib Rahman , K S M Tozammel Hossain , Enamul Hoque , Shafiq Joty , Md Rizwan Parvez

Safe and trustworthy use of Large Language Models (LLM) in the processing of healthcare documents and scientific papers could substantially help clinicians, scientists and policymakers in overcoming information overload and focusing on the…

Schema matching is a crucial task in data integration, involving the alignment of a source schema with a target schema to establish correspondence between their elements. This task is challenging due to textual and semantic heterogeneity,…

数据库 · 计算机科学 2024-05-31 Eitam Sheetrit , Menachem Brief , Moshik Mishaeli , Oren Elisha

Large-scale language models (LLMs) have achieved remarkable success across various language tasks but suffer from hallucinations and temporal misalignment. To mitigate these shortcomings, Retrieval-augmented generation (RAG) has been…

计算与语言 · 计算机科学 2024-04-30 Zhongzhen Huang , Kui Xue , Yongqi Fan , Linjie Mu , Ruoyu Liu , Tong Ruan , Shaoting Zhang , Xiaofan Zhang

Medical question-answering (QA) systems can benefit from advances in large language models (LLMs), but directly applying LLMs to the clinical domain poses challenges such as maintaining factual accuracy and avoiding hallucinations. In this…

计算与语言 · 计算机科学 2025-12-08 Tasnimul Hassan , Md Faisal Karim , Haziq Jeelani , Elham Behnam , Robert Green , Fayeq Jeelani Syed

Large language models (LLM) hold significant potential for applications in biomedicine, but they struggle with hallucinations and outdated knowledge. While retrieval-augmented generation (RAG) is generally employed to address these issues,…

计算与语言 · 计算机科学 2025-09-23 Jiwoong Sohn , Yein Park , Chanwoong Yoon , Sihyeon Park , Hyeon Hwang , Mujeen Sung , Hyunjae Kim , Jaewoo Kang

Retrieval-augmented generation (RAG) has emerged as a promising approach to enhance the performance of large language models (LLMs) in knowledge-intensive tasks such as those from medical domain. However, the sensitive nature of the medical…

计算与语言 · 计算机科学 2024-11-15 Nghia Trung Ngo , Chien Van Nguyen , Franck Dernoncourt , Thien Huu Nguyen

The emergent abilities of large language models (LLMs) have demonstrated great potential in solving medical questions. They can possess considerable medical knowledge, but may still hallucinate and are inflexible in the knowledge updates.…

计算与语言 · 计算机科学 2024-10-14 Guangzhi Xiong , Qiao Jin , Xiao Wang , Minjia Zhang , Zhiyong Lu , Aidong Zhang

Large Language Models (LLMs) generate responses to questions; however, their effectiveness is often hindered by sub-optimal quality of answers and occasional failures to provide accurate responses to questions. To address these challenges,…

计算与语言 · 计算机科学 2024-02-06 Liang Zhang , Katherine Jijo , Spurthi Setty , Eden Chung , Fatima Javid , Natan Vidra , Tommy Clifford

Large language models (LLMs) in biomedicine face a fundamental conflict between static parameter knowledge and the dynamic nature of clinical evidence. Retrieval-Augmented Generation (RAG) addresses this by grounding generation in external…

其他定量生物学 · 定量生物学 2025-12-19 Jiawei He , Boya Zhang , Hossein Rouhizadeh , Yingjian Chen , Rui Yang , Jin Lu , Xudong Chen , Nan Liu , Douglas Teodoro

This paper presents CaseGPT, an innovative approach that combines Large Language Models (LLMs) and Retrieval-Augmented Generation (RAG) technology to enhance case-based reasoning in the healthcare and legal sectors. The system addresses the…

信息检索 · 计算机科学 2024-07-12 Rui Yang

The versatility of large language models (LLMs) has been explored across various sectors, but their application in healthcare poses challenges, particularly in the domain of pharmaceutical contraindications where accurate and reliable…

人工智能 · 计算机科学 2025-08-11 Byeonghun Bang , Jongsuk Yoon , Dong-Jin Chang , Seho Park , Yong Oh Lee

Patient recruitment remains a major bottleneck in clinical trials, calling for scalable and automated solutions. We present TrialMatchAI, an AI-powered recommendation system that automates patient-to-trial matching by processing…

Large Language Models (LLMs) like GPT-4, MedPaLM-2, and Med-Gemini achieve performance competitively with human experts across various medical benchmarks. However, they still face challenges in making professional diagnoses akin to…

计算与语言 · 计算机科学 2024-08-23 Xiaohan Wang , Xiaoyan Yang , Yuqi Zhu , Yue Shen , Jian Wang , Peng Wei , Lei Liang , Jinjie Gu , Huajun Chen , Ningyu Zhang

Large language models (LLMs) have recently become the leading source of answers for users' questions online. Despite their ability to offer eloquent answers, their accuracy and reliability can pose a significant challenge. This is…

In our study, we evaluated large language model (LLM) performance on pharmacy licensure-style question-answering tasks and developed an external knowledge integration method to improve accuracy. We benchmarked ten LLMs with varying…

Large Language Models (LLMs) have demonstrated surprising performance across various natural language processing tasks. Recently, medical LLMs enhanced with domain-specific knowledge have exhibited excellent capabilities in medical…

计算与语言 · 计算机科学 2024-09-24 Jinqiang Wang , Huansheng Ning , Yi Peng , Qikai Wei , Daniel Tesfai , Wenwei Mao , Tao Zhu , Runhe Huang

Large language models (LLMs) have demonstrated powerful text generation capabilities, bringing unprecedented innovation to the healthcare field. While LLMs hold immense promise for applications in healthcare, applying them to real clinical…

计算与语言 · 计算机科学 2023-10-16 Rui Yang , Edison Marrese-Taylor , Yuhe Ke , Lechao Cheng , Qingyu Chen , Irene Li