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Transformer has been widely used in histopathology whole slide image (WSI) classification for the purpose of tumor grading, prognosis analysis, etc. However, the design of token-wise self-attention and positional embedding strategy in the…

计算机视觉与模式识别 · 计算机科学 2022-06-28 Yushan Zheng , Jun Li , Jun Shi , Fengying Xie , Zhiguo Jiang

Computational pathology needs whole-slide image (WSI) foundation models that transfer across diverse clinical tasks, yet current approaches remain largely slide-centric, often depend on private data and expensive paired-report supervision,…

计算机视觉与模式识别 · 计算机科学 2026-04-02 Yousef Kotp , Vincent Quoc-Huy Trinh , Christopher Pal , Mahdi S. Hosseini

Correct treatment of urothelial carcinoma patients is dependent on accurate grading and staging of the cancer tumour. This is determined manually by a pathologist by examining the histological whole-slide images (WSI). The large size of…

图像与视频处理 · 电气工程与系统科学 2019-09-12 Rune Wetteland , Kjersti Engan , Trygve Eftestøl , Vebjørn Kvikstad , Emilius A. M. Janssen

Supervised deep learning methods have achieved considerable success in medical image analysis, owing to the availability of large-scale and well-annotated datasets. However, creating such datasets for whole slide images (WSIs) in…

计算机视觉与模式识别 · 计算机科学 2024-06-10 Hao Wang , Euijoon Ahn , Jinman Kim

Few-shot learning presents a critical solution for cancer diagnosis in computational pathology (CPath), addressing fundamental limitations in data availability, particularly the scarcity of expert annotations and patient privacy…

计算机视觉与模式识别 · 计算机科学 2025-03-21 Zhengrui Guo , Conghao Xiong , Jiabo Ma , Qichen Sun , Lishuang Feng , Jinzhuo Wang , Hao Chen

Whole slide image (WSI) processing is becoming part of the key components of standard clinical diagnosis for various diseases. However, the direct application of conventional image processing algorithms to WSI faces certain obstacles…

计算机视觉与模式识别 · 计算机科学 2023-09-18 Yuanfeng Wu , Shaojie Li , Zhiqiang Du , Wentao Zhu

Researchers working on computational analysis of Whole Slide Images (WSIs) in histopathology have primarily resorted to patch-based modelling due to large resolution of each WSI. The large resolution makes WSIs infeasible to be fed directly…

计算机视觉与模式识别 · 计算机科学 2021-06-08 Suvidha Tripathi , Satish Kumar Singh , Hwee Kuan Lee

Breast cancer survival prediction in computational pathology presents a remarkable challenge due to tumor heterogeneity. For instance, different regions of the same tumor in the pathology image can show distinct morphological and molecular…

图像与视频处理 · 电气工程与系统科学 2025-03-25 Yang Luo , Shiru Wang , Jun Liu , Jiaxuan Xiao , Rundong Xue , Zeyu Zhang , Hao Zhang , Yu Lu , Yang Zhao , Yutong Xie

Recent advances in vision-language models (VLMs) have shown remarkable potential in bridging visual and textual modalities. In computational pathology, domain-specific VLMs, which are pre-trained on extensive histopathology image-text…

计算机视觉与模式识别 · 计算机科学 2025-03-03 Anh Tien Nguyen , Keunho Byeon , Kyungeun Kim , Jin Tae Kwak

This paper introduces the novel concept of few-shot weakly supervised learning for pathology Whole Slide Image (WSI) classification, denoted as FSWC. A solution is proposed based on prompt learning and the utilization of a large language…

计算机视觉与模式识别 · 计算机科学 2024-01-30 Linhao Qu , Xiaoyuan Luo , Kexue Fu , Manning Wang , Zhijian Song

Recently there have been many algorithms proposed for the classification of very high resolution whole slide images (WSIs). These new algorithms are mostly focused on finding novel ways to combine the information from small local patches…

计算机视觉与模式识别 · 计算机科学 2023-10-06 Long Nguyen , Aiden Nibali , Joshua Millward , Zhen He

Regions of Interest (ROI) contain morphological features in pathology whole slide images (WSI) are delimited with polygons[1]. These polygons are often represented in either a textual notation (with the array of edges) or in a binary mask…

图形学 · 计算机科学 2020-05-15 Erich Bremer , Jonas Almeida , Joel Saltz

Computational Pathology (CPATH) systems have the potential to automate diagnostic tasks. However, the artifacts on the digitized histological glass slides, known as Whole Slide Images (WSIs), may hamper the overall performance of CPATH…

计算机视觉与模式识别 · 计算机科学 2023-05-30 Neel Kanwal , Trygve Eftestol , Farbod Khoraminia , Tahlita CM Zuiverloon , Kjersti Engan

Pathology is the study of microscopic inspection of tissue, and a pathology diagnosis is often the medical gold standard to diagnose disease. Pathology images provide a unique challenge for computer-vision-based analysis: a single pathology…

Searching for similar images in archives of histology and histopathology images is a crucial task that may aid in patient matching for various purposes, ranging from triaging and diagnosis to prognosis and prediction. Whole slide images…

Remarkable strides in computational pathology have been made in the task-agnostic foundation model that advances the performance of a wide array of downstream clinical tasks. Despite the promising performance, there are still several…

In pathology, whole-slide images (WSI) based survival prediction has attracted increasing interest. However, given the large size of WSIs and the lack of pathologist annotations, extracting the prognostic information from WSIs remains a…

图像与视频处理 · 电气工程与系统科学 2021-10-25 Shuai Jiang , Arief A. Suriawinata , Saeed Hassanpour

Representation learning of pathology whole-slide images (WSIs) has primarily relied on weak supervision with Multiple Instance Learning (MIL). This approach leads to slide representations highly tailored to a specific clinical task.…

计算机视觉与模式识别 · 计算机科学 2025-03-25 Tim Lenz , Peter Neidlinger , Marta Ligero , Georg Wölflein , Marko van Treeck , Jakob Nikolas Kather

In modern cancer diagnostics, Whole Slide Imaging (WSI) is widely used to digitize tissue specimens for detailed, high-resolution examination; however, other diagnostic approaches, such as liquid biopsy and molecular testing, are also…

计算机视觉与模式识别 · 计算机科学 2025-07-02 Seyed Kahaki , Alexander R. Webber , Ghada Zamzmi , Adarsh Subbaswamy , Rucha Deshpande , Aldo Badano

The use of artificial intelligence to enable precision medicine and decision support systems through the analysis of pathology images has the potential to revolutionize the diagnosis and treatment of cancer. Such applications will depend on…