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The Frozen Section (FS) technique is a rapid and efficient method, taking only 15-30 minutes to prepare slides for pathologists' evaluation during surgery, enabling immediate decisions on further surgical interventions. However, FS process…
Frozen sectioning (FS) is the preparation method of choice for microscopic evaluation of tissues during surgical operations. The high speed of the procedure allows pathologists to rapidly assess the key microscopic features, such as tumour…
Full-color imaging is significant in digital pathology. Compared with a grayscale image or a pseudo-color image that only contains the contrast information, it can identify and detect the target object better with color texture information.…
Confocal laser endomicroscopy (CLE) allow on-the-fly in vivo intraoperative imaging in a discreet field of view, especially for brain tumors, rather than extracting tissue for examination ex vivo with conventional light microscopy.…
Infrared and visible image fusion aims to utilize the complementary information from two modalities to generate fused images with prominent targets and rich texture details. Most existing algorithms only perform pixel-level or feature-level…
Immunohistochemistry (IHC) staining plays a significant role in the evaluation of diseases such as breast cancer. The H&E-to-IHC transformation based on generative models provides a simple and cost-effective method for obtaining IHC images.…
Instead of directly utilizing an observed image including some outliers, noise or intensity inhomogeneity, the use of its ideal value (e.g. noise-free image) has a favorable impact on clustering. Hence, the accurate estimation of the…
The two primary types of Hematoxylin and Eosin (H&E) slides in histopathology are Formalin-Fixed Paraffin-Embedded (FFPE) and Fresh Frozen (FF). FFPE slides offer high quality histopathological images but require a labor-intensive…
The popular VQ-VAE models reconstruct images through learning a discrete codebook but suffer from a significant issue in the rapid quality degradation of image reconstruction as the compression rate rises. One major reason is that a higher…
Diffusion models have demonstrated significant potential in producing high-quality images in medical image translation to aid disease diagnosis, localization, and treatment. Nevertheless, current diffusion models have limited success in…
Visible and infrared image fusion (VIF) aims to combine information from visible and infrared images into a single fused image. Previous VIF methods usually employ a color space transformation to keep the hue and saturation from the…
A theoretical platform is developed for active elastic-wave sensing of (stationary and advancing) fractures along bi-material interfaces in layered composites. Damaged contact surfaces are characterized by a heterogeneous distribution of…
Deep learning models can generate virtual immunohistochemistry (IHC) stains from hematoxylin and eosin (H&E) images, offering a scalable and low-cost alternative to laboratory IHC. However, reliable evaluation of image quality remains a…
Immunofluorescent (IF) imaging is crucial for visualizing biomarker expressions, cell morphology and assessing the effects of drug treatments on sub-cellular components. IF imaging needs extra staining process and often requiring cell…
Compared to hematoxylin-eosin (H&E) staining, immunohistochemistry (IHC) not only maintains the structural features of tissue samples, but also provides high-resolution protein localization, which is essential for aiding in pathology…
Medical image segmentation plays an important role in computer-aided diagnosis. Existing methods mainly utilize spatial attention to highlight the region of interest. However, due to limitations of medical imaging devices, medical images…
Confocal laser endomicroscopy (CLE) is an advanced optical fluorescence technology undergoing assessment for applications in brain tumor surgery. Despite its promising potential, interpreting the unfamiliar gray tone images of fluorescent…
Immunohistochemical (IHC) staining serves as a valuable technique for detecting specific antigens or proteins through antibody-mediated visualization. However, the IHC staining process is both time-consuming and costly. To address these…
Fourier ptychographic microscopy (FPM) is a promising computational imaging technique with high resolution, wide field-of-view (FOV) and quantitative phase recovery. So far, a series of system errors that may corrupt the image quality of…
Effective lesion detection in medical image is not only rely on the features of lesion region,but also deeply relative to the surrounding information.However,most current methods have not fully utilize it.What is more,multi-scale feature…