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We introduce an explainability method for biomedical hypothesis generation systems, built on top of the novel Hypothesis Generation Context Retriever framework. Our approach combines semantic graph-based retrieval and relevant…

信息检索 · 计算机科学 2025-11-11 Ilya Tyagin , Saeideh Valipour , Aliaksandra Sikirzhytskaya , Michael Shtutman , Ilya Safro

Autonomous Driving Systems (ADS) use complex decision-making (DM) models with multimodal sensory inputs, making rigorous validation and verification (V&V) essential for safety and reliability. These models pose challenges in diagnosing…

软件工程 · 计算机科学 2025-10-07 Halit Eris , Stefan Wagner

Agent-based simulation is crucial for modeling complex human behavior, yet traditional approaches require extensive domain knowledge and large datasets. In data-scarce healthcare settings where historic and counterfactual data are limited,…

人工智能 · 计算机科学 2025-04-01 Sarah Martinson , Lingkai Kong , Cheol Woo Kim , Aparna Taneja , Milind Tambe

Medical large language models (LLMs) achieve impressive performance on standardized benchmarks, yet these evaluations fail to capture the complexity of real clinical encounters where patients exhibit memory gaps, limited health literacy,…

This paper explores the potential of using Large Language Models (LLMs) to automate the evaluation of responses in medical Question and Answer (Q\&A) systems, a crucial form of Natural Language Processing. Traditionally, human evaluation…

计算与语言 · 计算机科学 2024-09-04 Jack Krolik , Herprit Mahal , Feroz Ahmad , Gaurav Trivedi , Bahador Saket

The integration of Large Language Models (LLMs) into medical applications has sparked widespread interest across the healthcare industry, from drug discovery and development to clinical decision support, assisting telemedicine, medical…

计算与语言 · 计算机科学 2024-12-03 Zifeng Wang , Hanyin Wang , Benjamin Danek , Ying Li , Christina Mack , Hoifung Poon , Yajuan Wang , Pranav Rajpurkar , Jimeng Sun

Large Language Models (LLMs) are transforming scientific hypothesis generation and validation by enabling information synthesis, latent relationship discovery, and reasoning augmentation. This survey provides a structured overview of…

Machine reasoning has made great progress in recent years owing to large language models (LLMs). In the clinical domain, however, most NLP-driven projects mainly focus on clinical classification or reading comprehension, and under-explore…

Large language models (LLMs) have the potential to aid and improve human decision-making in classification tasks, not only by providing fairly accurate predictions, but also in their ability to generate cogent narrative explanations of…

人机交互 · 计算机科学 2026-05-25 Laura R. Marusich , Mary Grace Kozuch Dhooghe , Jonathan Z. Bakdash , Murat Kantarcioglu

Large language models (LLMs) show promise for supporting clinicians in diagnostic communication by generating explanations and guidance for patients. Yet their ability to produce outputs that are both understandable and empathetic remains…

计算与语言 · 计算机科学 2025-11-04 Jianzhou Yao , Shunchang Liu , Guillaume Drui , Rikard Pettersson , Alessandro Blasimme , Sara Kijewski

Leveraging outputs from multiple large language models (LLMs) is emerging as a method for harnessing their power across a wide range of tasks while mitigating their capacity for making errors, e.g., hallucinations. However, current…

计算与语言 · 计算机科学 2025-08-05 Ming Pok Ng , Junqi Jiang , Gabriel Freedman , Antonio Rago , Francesca Toni

Resolving ambiguities through interaction is a hallmark of natural language, and modeling this behavior is a core challenge in crafting AI assistants. In this work, we study such behavior in LMs by proposing a task-agnostic framework for…

计算与语言 · 计算机科学 2023-11-17 Michael J. Q. Zhang , Eunsol Choi

Clinical trial matching is the task of identifying trials for which patients may be potentially eligible. Typically, this task is labor-intensive and requires detailed verification of patient electronic health records (EHRs) against the…

The breakthrough of OpenAI o1 highlights the potential of enhancing reasoning to improve LLM. Yet, most research in reasoning has focused on mathematical tasks, leaving domains like medicine underexplored. The medical domain, though…

计算与语言 · 计算机科学 2024-12-30 Junying Chen , Zhenyang Cai , Ke Ji , Xidong Wang , Wanlong Liu , Rongsheng Wang , Jianye Hou , Benyou Wang

Large Language Models (LLMs) have emerged as transformative tools in the healthcare sector, demonstrating remarkable capabilities in natural language understanding and generation. However, their proficiency in numerical reasoning,…

人工智能 · 计算机科学 2025-01-27 Arjun R. Malghan

As large language models (LLMs) are increasingly deployed in sensitive domains such as healthcare, law, and education, the demand for transparent, interpretable, and accountable AI systems becomes more urgent. Explainable AI (XAI) acts as a…

计算机与社会 · 计算机科学 2025-05-28 Francisco Herrera

We propose a clinical decision support system (CDSS) for mental health diagnosis that combines the strengths of large language models (LLMs) and constraint logic programming (CLP). Having a CDSS is important because of the high complexity…

人工智能 · 计算机科学 2025-02-24 Brian Hyeongseok Kim , Chao Wang

Recent research has shown that hallucinations, omissions, and biases are prevalent in everyday use-cases of LLMs. However, chatbots used in medical contexts must provide consistent advice in situations where non-medical factors are…

计算与语言 · 计算机科学 2025-11-05 Jonathan Liu , Haoling Qiu , Jonathan Lasko , Damianos Karakos , Mahsa Yarmohammadi , Mark Dredze

Artificial intelligence (AI) is transforming the practice of science. Machine learning and large language models (LLMs) can generate hypotheses at a scale and speed far exceeding traditional methods, offering the potential to accelerate…

人工智能 · 计算机科学 2025-12-18 Cristina Cornelio , Takuya Ito , Ryan Cory-Wright , Sanjeeb Dash , Lior Horesh

Biomedical question answering (QA) requires accurate interpretation of complex medical knowledge. Large language models (LLMs) have shown promising capabilities in this domain, with retrieval-augmented generation (RAG) systems enhancing…

计算与语言 · 计算机科学 2025-10-21 Yingpeng Ning , Yuanyuan Sun , Ling Luo , Yanhua Wang , Yuchen Pan , Hongfei Lin