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Sepsis is a leading cause of mortality in intensive care units (ICUs), yet existing research often relies on outdated datasets, non-reproducible preprocessing pipelines, and limited coverage of clinical interventions. We introduce…

机器学习 · 计算机科学 2025-10-29 Yong Huang , Zhongqi Yang , Amir Rahmani

Sepsis is a life-threatening infectious syndrome associated with high mortality in intensive care units (ICUs). Early and accurate sepsis prediction (SP) is critical for timely intervention, yet remains challenging due to subtle early…

机器学习 · 计算机科学 2025-10-22 Zexi Tan , Tao Xie , Binbin Sun , Xiang Zhang , Yiqun Zhang , Yiu-Ming Cheung

Background: Sepsis-Associated Acute Kidney Injury (SA-AKI) leads to high mortality in intensive care. This study develops machine learning models using the Medical Information Mart for Intensive Care IV (MIMIC-IV) database to predict…

机器学习 · 计算机科学 2025-05-20 Shuheng Chen , Junyi Fan , Elham Pishgar , Kamiar Alaei , Greg Placencia , Maryam Pishgar

Sepsis is an important cause of mortality, especially in intensive care unit (ICU) patients. Developing novel methods to identify early mortality is critical for improving survival outcomes in sepsis patients. Using the MIMIC-III database,…

计算机与社会 · 计算机科学 2021-12-03 Jiyoung Shin , Yikuan Li , Yuan Luo

Sepsis is a life-threatening disease with high morbidity, mortality and healthcare costs. The early prediction and administration of antibiotics and intravenous fluids is considered crucial for the treatment of sepsis and can save…

计算与语言 · 计算机科学 2021-07-26 Fred Qin , Vivek Madan , Ujjwal Ratan , Zohar Karnin , Vishaal Kapoor , Parminder Bhatia , Taha Kass-Hout

Sepsis is a leading cause of death in the Intensive Care Units (ICU). Early detection of sepsis is critical for patient survival. In this paper, we propose a multimodal Transformer model for early sepsis prediction, using the physiological…

机器学习 · 计算机科学 2022-03-29 Yuqing Wang , Yun Zhao , Rachael Callcut , Linda Petzold

Within the intensive care unit (ICU), a wealth of patient data, including clinical measurements and clinical notes, is readily available. This data is a valuable resource for comprehending patient health and informing medical decisions, but…

机器学习 · 计算机科学 2023-12-13 Ryan King , Tianbao Yang , Bobak Mortazavi

Sepsis is the leading cause of death in non-coronary intensive care units. Moreover, a delay of antibiotic treatment of patients with severe sepsis by only few hours is associated with increased mortality. This insight makes accurate models…

We study multiple rule-based and machine learning (ML) models for sepsis detection. We report the first neural network detection and prediction results on three categories of sepsis. We have used the retrospective Medical Information Mart…

机器学习 · 计算机科学 2019-03-07 Avijit Mitra , Khalid Ashraf

Hypertension and atrial fibrillation (AF) often coexist in critically ill patients, significantly increasing mortality rates in the ICU. Early identification of high-risk individuals is crucial for targeted interventions. However, limited…

应用统计 · 统计学 2025-06-19 Shuheng Chen , Yong Si , Junyi Fan , Li Sun , Greg Placencia , Elham Pishgar , Kamiar Alaei , Maryam Pishgar

Objective: Sepsis is a life-threatening condition caused by severe infection leading to acute organ dysfunction. This study proposes a data-driven metric and a continuous reward function to optimize personalized heparin therapy in surgical…

机器学习 · 计算机科学 2025-12-15 Jiang Liu , Yujie Li , Chan Zhou , Yihao Xie , Qilong Sun , Xin Shu , Peiwei Li , Chunyong Yang , Yiziting Zhu , Jiaqi Zhu , Yuwen Chen , Bo An , Hao Wu , Bin Yi

Sepsis is one of the leading causes of death in Intensive Care Units (ICU). The strategy for treating sepsis involves the infusion of intravenous (IV) fluids and administration of antibiotics. Determining the optimal quantity of IV fluids…

人工智能 · 计算机科学 2020-09-18 Akash Gupta , Michael T. Lash , Senthil K. Nachimuthu

Sepsis is a leading cause of mortality in intensive care units (ICUs), representing a substantial medical challenge. The complexity of analyzing diverse vital signs to predict sepsis further aggravates this issue. While deep learning…

机器学习 · 计算机科学 2024-05-24 Yuwei Liu , Chen Dan , Anubhav Bhatti , Bingjie Shen , Divij Gupta , Suraj Parmar , San Lee

Sepsis is a leading cause of mortality in intensive care units (ICUs) and costs hospitals billions annually. Treating a septic patient is highly challenging, because individual patients respond very differently to medical interventions and…

机器学习 · 计算机科学 2017-05-24 Aniruddh Raghu , Matthieu Komorowski , Leo Anthony Celi , Peter Szolovits , Marzyeh Ghassemi

Sepsis is a potentially life threatening inflammatory response to infection or severe tissue damage. It has a highly variable clinical course, requiring constant monitoring of the patient's state to guide the management of intravenous…

机器学习 · 计算机科学 2022-02-21 Thesath Nanayakkara , Gilles Clermont , Christopher James Langmead , David Swigon

Sepsis, a dysregulated immune system response to infection, is among the leading causes of morbidity, mortality, and cost overruns in the Intensive Care Unit (ICU). Early prediction of sepsis can improve situational awareness amongst…

机器学习 · 计算机科学 2019-08-14 Supreeth P. Shashikumar , Christopher Josef , Ashish Sharma , Shamim Nemati

Heart attack remain one of the greatest contributors to mortality in the United States and globally. Patients admitted to the intensive care unit (ICU) with diagnosed heart attack (myocardial infarction or MI) are at higher risk of death.…

机器学习 · 计算机科学 2023-05-11 Munib Mesinovic , Peter Watkinson , Tingting Zhu

Objective: Sepsis is a life-threatening condition. Sequential Organ Failure Assessment (SOFA) score is commonly used to assess organ dysfunction and predict ICU mortality, but it is taken as a static measurement and fails to capture dynamic…

Sepsis is a leading cause of death in the ICU. It is a disease requiring complex interventions in a short period of time, but its optimal treatment strategy remains uncertain. Evidence suggests that the practices of currently used treatment…

机器学习 · 计算机科学 2022-07-15 Zeyu Wang , Huiying Zhao , Peng Ren , Yuxi Zhou , Ming Sheng

Sepsis is a severe condition responsible for many deaths in the United States and worldwide, making accurate prediction of outcomes crucial for timely and effective treatment. Previous studies employing machine learning faced limitations in…

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