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Dementia, a prevalent neurodegenerative condition, is a major manifestation of Alzheimer's disease (AD). As the condition progresses from mild to severe, it significantly impairs the individual's ability to perform daily tasks…

机器学习 · 计算机科学 2023-11-06 Md Gulzar Hussain , Ye Shiren

Several machine learning algorithms have been developed for the prediction of Alzheimer's disease and related dementia (ADRD) from spontaneous speech. However, none of these algorithms have been translated for the prediction of broader…

Alzheimer's disease (AD) is a neurodegenerative disorder marked by memory loss and cognitive decline, making early detection vital for timely intervention. However, early diagnosis is challenging due to the heterogeneous presentation of…

神经元与认知 · 定量生物学 2025-09-24 Ali Khazaee , Abdolreza Mohammadi , Ruairi O'Reilly

Early prediction of Alzheimer's disease (AD) is crucial for timely intervention and treatment. This study aims to use machine learning approaches to analyze longitudinal electronic health records (EHRs) of patients with AD and identify…

Alongside neuroimaging such as MRI scans and PET, Alzheimer's disease (AD) datasets contain valuable tabular data including AD biomarkers and clinical assessments. Existing computer vision approaches struggle to utilize this additional…

计算机视觉与模式识别 · 计算机科学 2023-08-30 Weichen Huang

Alzheimer's Disease (AD) is a prevalent neurodegenerative condition where early detection is vital. Handwriting, often affected early in AD, offers a non-invasive and cost-effective way to capture subtle motor changes. State-of-the-art…

计算机视觉与模式识别 · 计算机科学 2024-10-15 Changqing Gong , Huafeng Qin , Mounîm A. El-Yacoubi

Alzheimer's disease (AD) is a progressive and irreversible neurodegenerative disease. Early and precise diagnosis of AD is crucial for timely intervention and treatment planning to alleviate the progressive neurodegeneration. However, most…

图像与视频处理 · 电气工程与系统科学 2025-07-29 Wenlong Hou , Guangqian Yang , Ye Du , Yeung Lau , Lihao Liu , Junjun He , Ling Long , Shujun Wang

Accurate and efficient classification of Alzheimer's disease (AD) severity from brain magnetic resonance imaging (MRI) remains a critical challenge, particularly when limited data and model interpretability are of concern. In this work, we…

计算机视觉与模式识别 · 计算机科学 2026-01-06 Faisal Ahmed

Early screening for Alzheimer's Disease (AD) through speech presents a promising non-invasive approach. However, challenges such as limited data and the lack of fine-grained, adaptive feature selection often hinder performance. To address…

声音 · 计算机科学 2025-08-29 Yongqi Shao , Binxin Mei , Cong Tan , Hong Huo , Tao Fang

Alzheimer's disease (AD) is the most prevalent neurodegenerative disease; yet its currently available treatments are limited to stopping disease progression. Moreover, effectiveness of these treatments is not guaranteed due to the…

机器学习 · 计算机科学 2024-02-02 Diego Machado Reyes , Hanqing Chao , Juergen Hahn , Li Shen , Pingkun Yan

Alzheimer's disease (AD) is a neurodegenerative disorder affecting millions worldwide, necessitating early and accurate diagnosis for optimal patient management. In recent years, advancements in deep learning have shown remarkable potential…

Structural magnetic resonance imaging (MRI) studies have shown that Alzheimer's Disease (AD) induces both localised and widespread neural degenerative changes throughout the brain. However, the absence of segmentation that highlights brain…

图像与视频处理 · 电气工程与系统科学 2024-06-21 Chen Zheng

Alzheimer's Disease (AD) is a non-curable progressive neurodegenerative disorder that affects the human brain, leading to a decline in memory, cognitive abilities, and eventually, the ability to carry out daily tasks. Manual diagnosis of…

图像与视频处理 · 电气工程与系统科学 2024-09-13 Santanu Roy , Archit Gupta , Shubhi Tiwari , Palak Sahu

Early detection of dementia is critical for timely medical intervention and improved patient outcomes. Neuropsychological tests are widely used for cognitive assessment but have traditionally relied on manual scoring. Automatic dementia…

机器学习 · 计算机科学 2025-07-15 Liming Wang , Saurabhchand Bhati , Cody Karjadi , Rhoda Au , James Glass

Alzheimer's disease (AD) dementia is the most common form of dementia. With the emergence of disease-modifying therapies, predicting disease risk before symptom onset has become critical. We introduce DuAL-Net, a hybrid deep learning…

基因组学 · 定量生物学 2025-06-03 Eun Hye Lee , Taeho Jo

Alzheimer's Disease (AD) is a progressive neurodegenerative condition that adversely affects cognitive abilities. Language-related changes can be automatically identified through the analysis of outputs from linguistic assessment tasks,…

Alzheimer's disease (AD) is a heterogeneous, multifactorial neurodegenerative disorder characterized by beta-amyloid, pathologic tau, and neurodegeneration. There are no effective treatments for Alzheimer's disease at a late stage, urging…

定量方法 · 定量生物学 2023-08-28 Enze Xu , Jingwen Zhang , Jiadi Li , Qianqian Song , Defu Yang , Guorong Wu , Minghan Chen

Parkinson's disease (PD) is a neurodegenerative condition characterized by notable motor and non-motor manifestations. The assessment tool known as the Unified Parkinson's Disease Rating Scale (UPDRS) plays a crucial role in evaluating the…

声音 · 计算机科学 2025-02-14 Arman Mohammadigilani , Hani Attar , Hamidreza Ehsani Chimeh , Mostafa Karami

Multi-task learning (MTL) and attention mechanism have been proven to effectively extract robust acoustic features for various speech-related tasks in noisy environments. In this study, we propose an attention-based MTL (ATM) approach that…

音频与语音处理 · 电气工程与系统科学 2021-02-23 Chiang-Jen Peng , Yun-Ju Chan , Cheng Yu , Syu-Siang Wang , Yu Tsao , Tai-Shih Chi

Early diagnosis of Alzheimer's disease and related dementias (ADRD) is critical for timely intervention, yet most diagnoses are delayed until advanced stages. While comprehensive patient narratives are essential for accurate diagnosis,…