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Discrete mixture models provide a well-known basis for effective clustering algorithms, although technical challenges have limited their scope. In the context of gene-expression data analysis, a model is presented that mixes over a finite…

统计方法学 · 统计学 2012-11-12 Michael A. Newton , Lisa M. Chung

Various data modalities are common in real-world applications (e.g., electronic health records, medical images and clinical notes in healthcare). It is essential to develop multimodal learning methods to aggregate various information from…

机器学习 · 计算机科学 2025-11-06 Feng Wu , Tsai Hor Chan , Fuying Wang , Guosheng Yin , Lequan Yu

Diagnostic test accuracy studies typically report the number of true positives, false positives, true negatives and false negatives. There usually exists a negative association between the number of true positives and true negatives,…

统计方法学 · 统计学 2015-11-06 Aristidis K. Nikoloulopoulos

Over the last decade, a large variety of clustering algorithms have been developed to detect coregulatory relationships among genes from microarray gene expression data. Model based clustering approaches have emerged as statistically well…

定量方法 · 定量生物学 2008-01-15 Anagha Joshi , Yves Van de Peer , Tom Michoel

We propose two approaches for selecting variables in latent class analysis (i.e.,mixture model assuming within component independence), which is the common model-based clustering method for mixed data. The first approach consists in…

统计计算 · 统计学 2017-03-08 Matthieu Marbac , Mohammed Sedki

This paper introduces the multivariate beta mixture model (MBMM), a new probabilistic model for soft clustering. MBMM adapts to diverse cluster shapes because of the flexible probability density function of the multivariate beta…

机器学习 · 计算机科学 2024-02-22 Yung-Peng Hsu , Hung-Hsuan Chen

Finite Gaussian mixture models are widely used for model-based clustering of continuous data. Nevertheless, since the number of model parameters scales quadratically with the number of variables, these models can be easily…

统计方法学 · 统计学 2018-09-25 Michael Fop , Thomas Brendan Murphy , Luca Scrucca

A bivariate copula mixed model has been recently proposed to synthesize diagnostic test accuracy studies and it has been shown that is superior to the standard generalized linear mixed model (GLMM) in this context. Here we call trivariate…

统计方法学 · 统计学 2017-11-09 Aristidis K. Nikoloulopoulos

The cluster-weighted model (CWM) is a mixture model with random covariates which allows for flexible clustering and density estimation of a random vector composed by a response variable and by a set of covariates. In this class of models,…

统计方法学 · 统计学 2013-08-06 Salvatore Ingrassia , Antonio Punzo

In this article, a copula-based method for mixed regression models is proposed, where the conditional distribution of the response variable, given covariates, is modelled by a parametric family of continuous or discrete distributions, and…

统计方法学 · 统计学 2025-01-13 Pavel Krupskii , Bouchra R Nasri , Bruno N Remillard

Clustering mixed data presents numerous challenges inherent to the very heterogeneous nature of the variables. A clustering algorithm should be able, despite of this heterogeneity, to extract discriminant pieces of information from the…

机器学习 · 计算机科学 2022-05-10 Robin Fuchs , Denys Pommeret , Cinzia Viroli

Finite mixture models are a useful statistical model class for clustering and density approximation. In the Bayesian framework finite mixture models require the specification of suitable priors in addition to the data model. These priors…

统计方法学 · 统计学 2024-07-09 Bettina Grün , Gertraud Malsiner-Walli

Determining the optimal number and identity of structural clusters from an ensemble of molecular configurations continues to be a challenge. Recent structural clustering methods have focused on the use of internal coordinates due to the…

化学物理 · 物理学 2023-01-11 Heidi Klem , Glen M. Hocky , Martin McCullagh

Functional data analysis (FDA) is an important modern paradigm for handling infinite-dimensional data. An important task in FDA is model-based clustering, which organizes functional populations into groups via subpopulation structures. The…

统计计算 · 统计学 2017-02-14 Hien D Nguyen , Geoffrey J McLachlan , Jeremy F P Ullmann , Andrew L Janke

Dirichlet Process Mixture Models (DPMMs) are widely used to address clustering problems. Their main advantage lies in their ability to automatically estimate the number of clusters during the inference process through the Bayesian…

机器学习 · 统计学 2023-12-19 Reda Khoufache , Mustapha Lebbah , Hanene Azzag , Etienne Goffinet , Djamel Bouchaffra

A model based clustering procedure for data of mixed type, clustMD, is developed using a latent variable model. It is proposed that a latent variable, following a mixture of Gaussian distributions, generates the observed data of mixed type.…

统计方法学 · 统计学 2015-11-06 Damien McParland , Isobel Claire Gormley

Learning the joint dependence of discrete variables is a fundamental problem in machine learning, with many applications including prediction, clustering and dimensionality reduction. More recently, the framework of copula modeling has…

机器学习 · 统计学 2013-11-15 Alfredo Kalaitzis , Ricardo Silva

Do expert-defined or diagnostically-labeled data groups align with clusters inferred through statistical modeling? If not, where do discrepancies between predefined labels and model-based groupings occur and why? In this work, we introduce…

统计方法学 · 统计学 2026-03-18 Patricia Puchhammer , Ines Wilms , Peter Filzmoser

This paper presents a method for fitting a copula-driven generalized linear mixed models. For added flexibility, the skew-normal copula is adopted for fitting. The correlation matrix of the skew-normal copula is used to capture the…

统计方法学 · 统计学 2017-08-01 Kalyan Das , Mohamad Elmasri , Arusharka Sen

Linear mixed models are widely used for clustered data, but their reliance on parametric forms limits flexibility in complex and high-dimensional settings. In contrast, gradient boosting methods achieve high predictive accuracy through…

机器学习 · 统计学 2025-11-04 Mitchell L. Prevett , Francis K. C. Hui , Zhi Yang Tho , A. H. Welsh , Anton H. Westveld