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Pulsative signals such as the electrocardiogram (ECG) are extensively collected as part of routine clinical care. However, noisy and poor-quality recordings are a major issue for signals collected using mobile health systems, decreasing the…

机器学习 · 计算机科学 2023-11-15 Alexander Jenkins , Zehua Chen , Fu Siong Ng , Danilo Mandic

Unsupervised anomaly detection (UAD) in medical imaging is crucial for identifying pathological abnormalities without requiring extensive labeled data. However, existing diffusion-based UAD models rely solely on imaging features, limiting…

计算机视觉与模式识别 · 计算机科学 2025-05-26 Harim Kim , Yuhan Wang , Minkyu Ahn , Heeyoul Choi , Yuyin Zhou , Charmgil Hong

Emotion recognition based on Electroencephalography (EEG) has gained significant attention and diversified development in fields such as neural signal processing and affective computing. However, the unique brain anatomy of individuals…

信号处理 · 电气工程与系统科学 2024-05-31 Yihang Dong , Xuhang Chen , Yanyan Shen , Michael Kwok-Po Ng , Tao Qian , Shuqiang Wang

Data scarcity in pharmaceutical research has led to reliance on labour-intensive trial-and-error approaches for development rather than data-driven methods. While Machine Learning offers a solution, existing datasets are often small and…

Molecule generation, especially generating 3D molecular geometries from scratch (i.e., 3D \textit{de novo} generation), has become a fundamental task in drug designs. Existing diffusion-based 3D molecule generation methods could suffer from…

机器学习 · 计算机科学 2022-09-14 Lei Huang , Hengtong Zhang , Tingyang Xu , Ka-Chun Wong

Integrating multi-modal clinical data, such as electronic health records (EHR) and chest X-ray images (CXR), is particularly beneficial for clinical prediction tasks. However, in a temporal setting, multi-modal data are often inherently…

计算机视觉与模式识别 · 计算机科学 2024-10-24 Wenfang Yao , Chen Liu , Kejing Yin , William K. Cheung , Jing Qin

Medical Decision-Making (MDM) is a complex process requiring substantial domain-specific expertise to effectively synthesize heterogeneous and complicated clinical information. While recent advancements in Large Language Models (LLMs) show…

人工智能 · 计算机科学 2025-08-20 Liuxin Bao , Zhihao Peng , Xiaofei Zhou , Runmin Cong , Jiyong Zhang , Yixuan Yuan

Data scarcity in the brain-computer interface field can be alleviated through the use of generative models, specifically diffusion models. While diffusion models have previously been successfully applied to electroencephalogram (EEG) data,…

机器学习 · 计算机科学 2024-11-05 Guido Klein , Pierre Guetschel , Gianluigi Silvestri , Michael Tangermann

Deep learning methods exhibit promising performance for predictive modeling in healthcare, but two important challenges remain: -Data insufficiency:Often in healthcare predictive modeling, the sample size is insufficient for deep learning…

机器学习 · 计算机科学 2017-04-04 Edward Choi , Mohammad Taha Bahadori , Le Song , Walter F. Stewart , Jimeng Sun

Machine learning (ML) and deep learning (DL) techniques have been widely applied to analyze electroencephalography (EEG) signals for disease diagnosis and brain-computer interfaces (BCI). The integration of multimodal data has been shown to…

信号处理 · 电气工程与系统科学 2025-01-16 Siqi Zhao , Wangyang Li , Xiru Wang , Stevie Foglia , Hongzhao Tan , Bohan Zhang , Ameer Hamoodi , Aimee Nelson , Zhen Gao

Continuous Conditional Generative Modeling (CCGM) estimates high-dimensional data distributions, such as images, conditioned on scalar continuous variables (aka regression labels). While Continuous Conditional Generative Adversarial…

计算机视觉与模式识别 · 计算机科学 2025-08-19 Xin Ding , Yongwei Wang , Kao Zhang , Z. Jane Wang

Synthetic data generation is a promising solution to address privacy issues with the distribution of sensitive health data. Recently, diffusion models have set new standards for generative models for different data modalities. Also very…

信号处理 · 电气工程与系统科学 2023-06-16 Juan Miguel Lopez Alcaraz , Nils Strodthoff

Accurate cancer survival prediction requires integration of diverse data modalities that reflect the complex interplay between imaging, clinical parameters, and textual reports. However, existing multimodal approaches suffer from simplistic…

机器学习 · 计算机科学 2025-07-01 Aakash Tripathi , Asim Waqas , Matthew B. Schabath , Yasin Yilmaz , Ghulam Rasool

Electronic Health Record (EHR) data encompass diverse modalities -- text, images, and medical codes -- that are vital for clinical decision-making. To process these complex data, multimodal AI (MAI) has emerged as a powerful approach for…

机器学习 · 计算机科学 2026-03-03 Nikkie Hooman , Zhongjie Wu , Eric C. Larson , Mehak Gupta

Navigating the vast chemical space of molecular structures to design novel drug molecules with desired target properties remains a central challenge in drug discovery. Recent advances in generative models offer promising solutions. This…

In contemporary scientific research, understanding the distinction between correlation and causation is crucial. While correlation is a widely used analytical standard, it does not inherently imply causation. This paper addresses the…

机器学习 · 计算机科学 2023-12-27 Cao Zhihao , Qu Hongchun

Decoding motor imagery (MI) electroencephalogram (EEG) signals, a key non-invasive brain-computer interface (BCI) paradigm for controlling external systems, has been significantly advanced by deep learning. However, cross-subject MI-EEG…

机器学习 · 计算机科学 2026-03-26 Jinzhou Wu , Baoping Tang , Qikang Li , Yi Wang , Cheng Li , Shujian Yu

Computational biology offers immense potential for reducing the high costs and protracted cycles of new drug development through adverse drug reaction (ADR) prediction. However, current methods remain impeded by drug data scarcity-induced…

机器学习 · 计算机科学 2026-01-06 Yuyan Pi , Min Jin , Wentao Xie , Xinhua Liu

The widespread emergence of smart devices for ECG has sparked demand for intelligent single-lead ECG-based diagnostic systems. However, it is challenging to develop a single-lead-based ECG interpretation model for multiple diseases…

人工智能 · 计算机科学 2023-01-31 Yuzhen Qin , Li Sun , Hui Chen , Wei-qiang Zhang , Wenming Yang , Jintao Fei , Guijin Wang

Deep learning in cardiac MRI (CMR) is fundamentally constrained by both data scarcity and privacy regulations. This study systematically benchmarks three generative architectures: Denoising Diffusion Probabilistic Models (DDPM), Latent…

计算机视觉与模式识别 · 计算机科学 2026-03-05 Madhura Edirisooriya , Dasuni Kawya , Ishan Kumarasinghe , Isuri Devindi , Mary M. Maleckar , Roshan Ragel , Isuru Nawinne , Vajira Thambawita
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