中文
相关论文

相关论文: DrugImproverGPT: A Large Language Model for Drug O…

200 篇论文

In an era where tool-augmented AI agents are becoming increasingly vital, our findings highlight the ability of Group Relative Policy Optimization (GRPO) to empower SLMs, which are traditionally constrained in tool use. The ability to use…

计算与语言 · 计算机科学 2025-09-10 Dhruvi Paprunia , Vansh Kharidia , Pankti Doshi

Objective To solve major clinical natural language processing (NLP) tasks using a unified text-to-text learning architecture based on a generative large language model (LLM) via prompt tuning. Methods We formulated 7 key clinical NLP tasks…

计算与语言 · 计算机科学 2023-12-12 Cheng Peng , Xi Yang , Aokun Chen , Zehao Yu , Kaleb E Smith , Anthony B Costa , Mona G Flores , Jiang Bian , Yonghui Wu

Large language models (LLMs) have shown impressive capabilities in natural language processing tasks, including dialogue generation. This research aims to conduct a novel comparative analysis of two prominent techniques, fine-tuning with…

Aligning large language models (LLMs) with human preferences is essential for safe and useful LLMs. Previous works mainly adopt reinforcement learning (RLHF) and direct preference optimization (DPO) with human feedback for alignment.…

计算与语言 · 计算机科学 2023-10-03 Tianci Xue , Ziqi Wang , Heng Ji

General-purpose Large Language Models (LLMs) are frequently fine-tuned through supervised fine-tuning (SFT) to enhance performance in specific domains. Better results can be achieved by distilling the chain-of-thought of a larger model at…

机器学习 · 计算机科学 2026-03-24 Andrey Goncharov , Daniil Vyazhev , Petr Sychev , Edvard Khalafyan , Alexey Zaytsev

Artificial intelligence (AI) is widely deployed to solve problems related to marketing attribution and budget optimization. However, AI models can be quite complex, and it can be difficult to understand model workings and insights without…

计算与语言 · 计算机科学 2024-04-23 Yilin Gao , Sai Kumar Arava , Yancheng Li , James W. Snyder

Seed implant brachytherapy (SIBT) is an effective cancer treatment modality; however, clinical planning often relies on manual adjustment of objective function weights, leading to inefficiencies and suboptimal results. This study proposes…

医学物理 · 物理学 2025-09-11 Zhuo Xiao , Qinglong Yao , Jingjing Wang , Fugen Zhou , Bo Liu , Haitao Sun , Zhe Ji , Yuliang Jiang , Junjie Wang , Qiuwen Wu

Iterative refinement has been a promising paradigm to enable large language models (LLMs) to resolve difficult reasoning and problem-solving tasks. One of the key challenges, however, is how to effectively search through the enormous search…

人工智能 · 计算机科学 2025-10-09 Daria Ozerova , Ekaterina Trofimova

Large language models (LLMs) deliver impressive results but face challenges from increasing model sizes and computational costs. Structured pruning reduces model size and speeds up inference but often causes uneven degradation across…

计算与语言 · 计算机科学 2025-05-28 Hexuan Deng , Wenxiang Jiao , Xuebo Liu , Jing Li , Min Zhang , Zhaopeng Tu

We show that large language model (LLMs) can be transformed via supervised fine-tuning (SFT) of engineered prompts into SmileyLlama for exploring the chemical space of drug molecules. We benchmark SmileyLlama against pre-trained LLMs and…

Loop transformations are semantics-preserving optimization techniques, widely used to maximize objectives such as parallelism. Despite decades of research, applying the optimal composition of loop transformations remains challenging due to…

编程语言 · 计算机科学 2025-12-19 Yijie Zhi , Yayu Cao , Jianhua Dai , Xiaoyang Han , Jingwen Pu , Qingran Wu , Sheng Cheng , Ming Cai

The advancement of large language models (LLMs) has opened new frontiers in natural language processing, particularly in specialized domains like healthcare. In this paper, we propose the Incremental Curriculum-Based Fine-Tuning (ICFT)…

计算与语言 · 计算机科学 2025-02-04 Robert Long , Eric Gonzalez , Harrison Fuller

Text data augmentation is a widely used strategy for mitigating data sparsity in natural language processing (NLP), particularly in low-resource settings where limited samples hinder effective semantic modeling. While augmentation can…

计算与语言 · 计算机科学 2025-07-17 Payal Bhattad , Sai Manoj Pudukotai Dinakarrao , Anju Gupta

Large Language Models (LLMs) have demonstrated remarkable capabilities across various tasks, with their performance heavily dependent on the quality of input prompts. While prompt engineering has proven effective, it typically relies on…

神经与进化计算 · 计算机科学 2025-04-17 Xavier Sécheresse , Jacques-Yves Guilbert--Ly , Antoine Villedieu de Torcy

Reinforcement learning (RL) has become a cornerstone for fine-tuning Large Language Models (LLMs), with Proximal Policy Optimization (PPO) serving as the de facto standard algorithm. Despite its ubiquity, we argue that the core ratio…

机器学习 · 计算机科学 2026-05-27 Penghui Qi , Xiangxin Zhou , Zichen Liu , Tianyu Pang , Chao Du , Min Lin , Wee Sun Lee

A multitude of industries depend on accurate and reasonable tabular data augmentation for their business processes. Contemporary methodologies in generating tabular data revolve around utilizing Generative Adversarial Networks (GAN) or…

机器学习 · 计算机科学 2025-02-25 Shuo Yang , Chenchen Yuan , Yao Rong , Felix Steinbauer , Gjergji Kasneci

In the pursuit of efficient automated content creation, procedural generation, leveraging modifiable parameters and rule-based systems, emerges as a promising approach. Nonetheless, it could be a demanding endeavor, given its intricate…

计算机视觉与模式识别 · 计算机科学 2024-05-30 Chunyi Sun , Junlin Han , Weijian Deng , Xinlong Wang , Zishan Qin , Stephen Gould

A key challenge in applying reinforcement learning (RL) to diffusion large language models (dLLMs) lies in the intractability of their likelihood functions, which are essential for the RL objective, necessitating corresponding approximation…

机器学习 · 计算机科学 2025-10-15 Nianyi Lin , Jiajie Zhang , Lei Hou , Juanzi Li

Post-training has become central to turning pretrained large language models (LLMs) into aligned, capable, and deployable systems. Recent progress spans supervised fine-tuning (SFT), preference optimization, reinforcement learning (RL),…

In recent years, groundbreaking advancements in natural language processing have culminated in the emergence of powerful large language models (LLMs), which have showcased remarkable capabilities across a vast array of domains, including…

计算与语言 · 计算机科学 2023-12-11 Microsoft Research AI4Science , Microsoft Azure Quantum