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How can we tell whether two neural networks utilize the same internal processes for a particular computation? This question is pertinent for multiple subfields of neuroscience and machine learning, including neuroAI, mechanistic…

神经元与认知 · 定量生物学 2023-10-31 Mitchell Ostrow , Adam Eisen , Leo Kozachkov , Ila Fiete

The advent of high-throughput sequencing technologies has lead to vast comparative genome sequences. The construction of gene-gene interaction networks or dependence graphs on the genome scale is vital for understanding the regulation of…

统计方法学 · 统计学 2023-03-06 Xinyao Fan , Harry Joe , Yongjin Park

The concept of a random process has been recently extended to graph signals, whereby random graph processes are a class of multivariate stochastic processes whose coefficients are matrices with a \textit{graph-topological} structure. The…

信号处理 · 电气工程与系统科学 2020-03-13 Thiernithi Variddhisai , Danilo Mandic

Graph representation learning is a fundamental problem for modeling relational data and benefits a number of downstream applications. Traditional Bayesian-based graph models and recent deep learning based GNN either suffer from…

机器学习 · 计算机科学 2024-03-27 Hanxuan Yang , Qingchao Kong , Wenji Mao

Comprehending the interplay between spatial and temporal characteristics of neural dynamics can contribute to our understanding of information processing in the human brain. Graph neural networks (GNNs) provide a new possibility to…

神经元与认知 · 定量生物学 2022-04-29 Simon Wein , Alina Schüller , Ana Maria Tomé , Wilhelm M. Malloni , Mark W. Greenlee , Elmar W. Lang

Stochastically evolving geometric systems are studied in shape analysis and computational anatomy for modelling random evolutions of human organ shapes. The notion of geodesic paths between shapes is central to shape analysis and has a…

数值分析 · 数学 2022-12-01 Alexis Arnaudon , Frank van der Meulen , Moritz Schauer , Stefan Sommer

Cells regulate themselves via dizzyingly complex biochemical processes called signaling pathways. These are usually depicted as a network, where nodes represent proteins and edges indicate their influence on each other. In order to…

分子网络 · 定量生物学 2021-01-13 David Merrell , Anthony Gitter

Face information is mainly concentrated among facial key points, and frontier research has begun to use graph neural networks to segment faces into patches as nodes to model complex face representations. However, these methods construct…

计算机视觉与模式识别 · 计算机科学 2025-02-11 Yiping Zhang , Yuntao Shou , Wei Ai , Tao Meng , Keqin Li

Modern histopathological image analysis relies on the segmentation of cell structures to derive quantitative metrics required in biomedical research and clinical diagnostics. State-of-the-art deep learning approaches predominantly apply…

图像与视频处理 · 电气工程与系统科学 2022-01-12 Yoav Alon , Huiyu Zhou

Heterogeneous presentation of a neurological disorder suggests potential differences in the underlying pathophysiological changes that occur in the brain. We propose to model heterogeneous patterns of functional network differences using a…

机器学习 · 计算机科学 2021-04-16 Nicha C. Dvornek , Xiaoxiao Li , Juntang Zhuang , Pamela Ventola , James S. Duncan

Biological systems are governed by structured molecular interactions, where pathways, regulatory circuits, and functional gene relationships shape cellular behavior and disease progression. Much of this knowledge is naturally represented as…

机器学习 · 计算机科学 2026-05-26 Yuwei Xue , Sakib Mostafa , James Zou , Joseph Liao , Maximilian Diehn , Ash A. Alizadeh , Lei Xing , Md. Tauhidul Islam

Graph convolutional networks (GCNs) have emerged as a powerful alternative to multiple instance learning with convolutional neural networks in digital pathology, offering superior handling of structural information across various spatial…

图像与视频处理 · 电气工程与系统科学 2024-03-25 Victor Ibañez , Przemyslaw Szostak , Quincy Wong , Konstanty Korski , Samaneh Abbasi-Sureshjani , Alvaro Gomariz

Gait disorder recognition plays a crucial role in the early diagnosis and monitoring of movement disorders. Existing approaches, including spatio-temporal graph convolutional networks (ST-GCNs), often face high memory demands and struggle…

计算机视觉与模式识别 · 计算机科学 2025-09-23 Zakariae Zrimek , Youssef Mourchid , Mohammed El Hassouni

In genome-scale constraint-based metabolic models, gene deletion strategies are essential for achieving growth-coupled production, where cell growth and target metabolite synthesis occur simultaneously. Despite the inherently networked…

定量方法 · 定量生物学 2026-04-10 Ziwei Yang , Takeyuki Tamura

Background: Timely, uncertainty-aware forecasting from irregular electronic health records (EHR) can support critical-care decisions, yet most approaches either impute to a grid or sacrifice interpretability. We introduce StructGP, a…

机器学习 · 计算机科学 2026-05-01 Ivan Lerner , Jean Feydy , Alexandre Kalimouttou , Anita Burgun , Francis Bach

Predicting genetic perturbations enables the identification of potentially crucial genes prior to wet-lab experiments, significantly improving overall experimental efficiency. Since genes are the foundation of cellular life, building gene…

定量方法 · 定量生物学 2025-05-09 Changxi Chi , Jun Xia , Jingbo Zhou , Jiabei Cheng , Chang Yu , Stan Z. Li

Single-cell trajectory analysis aims to reconstruct the biological developmental processes of cells as they evolve over time, leveraging temporal correlations in gene expression. During cellular development, gene expression patterns…

应用统计 · 统计学 2026-03-30 Junhao Zhu , Kevin Zhang , Zhaolei Zhang , Dehan Kong

Theory of graphical models has matured over more than three decades to provide the backbone for several classes of models that are used in a myriad of applications such as genetic mapping of diseases, credit risk evaluation, reliability and…

机器学习 · 统计学 2014-11-13 Henrik Nyman , Johan Pensar , Timo Koski , Jukka Corander

Complex systems which can be represented in the form of static and dynamic graphs arise in different fields, e.g. communication, engineering and industry. One of the interesting problems in analysing dynamic network structures is to monitor…

机器学习 · 计算机科学 2020-11-13 Anna Malinovskaya , Philipp Otto , Torben Peters

Graph Convolutional Networks (GCNs) achieve great success in non-Euclidean structure data processing recently. In existing studies, deeper layers are used in CCNs to extract deeper features of Euclidean structure data. However, for…

机器学习 · 计算机科学 2022-03-14 Junhua Ma , Jiajun Li , Xueming Li , Xu Li
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