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相关论文: Controllable Sequence Editing for Biological and C…

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Neural sequence to sequence models are well established for applications which can be cast as mapping a single input sequence into a single output sequence. In this work, we focus on cases where generation is conditioned on both a short…

计算与语言 · 计算机科学 2019-11-25 Xinyi Wang , Jason Weston , Michael Auli , Yacine Jernite

We present GO-CBED, a goal-oriented Bayesian framework for sequential causal experimental design. Unlike conventional approaches that select interventions aimed at inferring the full causal model, GO-CBED directly maximizes the expected…

机器学习 · 计算机科学 2025-07-11 Zheyu Zhang , Jiayuan Dong , Jie Liu , Xun Huan

Controllable text generation concerns two fundamental tasks of wide applications, namely generating text of given attributes (i.e., attribute-conditional generation), and minimally editing existing text to possess desired attributes (i.e.,…

计算与语言 · 计算机科学 2022-01-25 Zhiting Hu , Li Erran Li

Generative models lack rigorous statistical guarantees for their outputs and are therefore unreliable in safety-critical applications. In this work, we propose Sequential Conformal Prediction for Generative Models (SCOPE-Gen), a sequential…

机器学习 · 计算机科学 2025-02-18 Klaus-Rudolf Kladny , Bernhard Schölkopf , Michael Muehlebach

Counterfactual explanations (CFs) provide human-interpretable insights into model's predictions by identifying minimal changes to input features that would alter the model's output. However, existing methods struggle to generate multiple…

机器学习 · 计算机科学 2026-02-20 Oleksii Furman , Patryk Marszałek , Jan Masłowski , Piotr Gaiński , Maciej Zięba , Marek Śmieja

Machine learning models are widely used in real-world applications. However, their complexity makes it often challenging to interpret the rationale behind their decisions. Counterfactual explanations (CEs) have emerged as a viable solution…

机器学习 · 计算机科学 2024-03-04 Muhammad Suffian , Jose M. Alonso-Moral , Alessandro Bogliolo

In a controlled experiment of sequence-to-sequence approaches for the task of sentence correction, we find that character-based models are generally more effective than word-based models and models that encode subword information via…

计算与语言 · 计算机科学 2017-07-31 Allen Schmaltz , Yoon Kim , Alexander M. Rush , Stuart M. Shieber

Counterfactual Explanations (CEs) help address the question: How can the factors that influence the prediction of a predictive model be changed to achieve a more favorable outcome from a user's perspective? Thus, they bear the potential to…

机器学习 · 计算机科学 2023-11-27 Xuan Zhao , Klaus Broelemann , Gjergji Kasneci

AI-assisted protein design has emerged as a critical tool for advancing biotechnology, as deep generative models have demonstrated their reliability in this domain. However, most existing models primarily utilize protein sequence or…

计算工程、金融与科学 · 计算机科学 2026-05-27 Changjian Zhou , Yuexi Qiu , Jia Song

Partial observations of continuous time-series dynamics at arbitrary time stamps exist in many disciplines. Fitting this type of data using statistical models with continuous dynamics is not only promising at an intuitive level but also has…

机器学习 · 计算机科学 2021-10-29 Ruizhi Deng , Marcus A. Brubaker , Greg Mori , Andreas M. Lehrmann

Machine learning models perform well on several healthcare tasks and can help reduce the burden on the healthcare system. However, the lack of explainability is a major roadblock to their adoption in hospitals. \textit{How can the decision…

机器学习 · 计算机科学 2023-06-13 Supriya Nagesh , Nina Mishra , Yonatan Naamad , James M. Rehg , Mehul A. Shah , Alexei Wagner

Estimating causal effects from observational data is inherently challenging due to the lack of observable counterfactual outcomes and even the presence of unmeasured confounding. Traditional methods often rely on restrictive, untestable…

统计方法学 · 统计学 2025-04-07 Li Chen , Xiaotong Shen , Wei Pan

Background: Stepped wedge cluster randomized trials (SW-CRTs) involve sequential measurements within clusters over time. Initially, all clusters start in the control condition before crossing over to the intervention on a staggered…

统计方法学 · 统计学 2026-01-21 Jale Basten , Katja Ickstadt , Nina Timmesfeld

Classifier-Free Guidance (CFG) is widely used to improve conditional fidelity in diffusion models, but its impact on sampling dynamics remains poorly understood. Prior studies, often restricted to unimodal conditional distributions or…

机器学习 · 计算机科学 2026-02-19 Cheng Jin , Qitan Shi , Yuantao Gu

As large-scale language models become the standard for text generation, there is a greater need to tailor the generations to be more or less concise, targeted, and informative, depending on the audience/application. Existing control…

计算与语言 · 计算机科学 2024-02-23 Samraj Moorjani , Adit Krishnan , Hari Sundaram

Predictive process analytics focuses on predicting future states, such as the outcome of running process instances. These techniques often use machine learning models or deep learning models (such as LSTM) to make such predictions. However,…

机器学习 · 计算机科学 2023-03-29 Olusanmi Hundogan , Xixi Lu , Yupei Du , Hajo A. Reijers

We present a training-free framework for continuous and controllable image editing at test time for text-conditioned generative models. In contrast to prior approaches that rely on additional training or manual user intervention, we find…

计算机视觉与模式识别 · 计算机科学 2026-03-19 Yigit Ekin , Yossi Gandelsman

Simulating in silico cellular responses to interventions is a promising direction to accelerate high-content image-based assays, critical for advancing drug discovery and gene editing. To support this, we introduce MorphGen, a…

定量方法 · 定量生物学 2025-10-13 Berker Demirel , Marco Fumero , Theofanis Karaletsos , Francesco Locatello

Controllable text generation systems often leverage control codes to direct various properties of the output like style and length. Inspired by recent work on causal inference for NLP, this paper reveals a previously overlooked flaw in…

计算与语言 · 计算机科学 2022-10-10 Junyi Chai , Reid Pryzant , Victor Ye Dong , Konstantin Golobokov , Chenguang Zhu , Yi Liu

Counterfactual simulation - exploring hypothetical consequences under alternative clinical scenarios - holds promise for transformative applications such as personalized medicine and in silico trials. However, it remains challenging due to…

机器学习 · 计算机科学 2026-04-06 Yu Akagi , Tomohisa Seki , Toru Takiguchi , Hiromasa Ito , Yoshimasa Kawazoe , Kazuhiko Ohe