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The abrupt outbreak and transmission of biological diseases has always been a long-time concern of humankind. For long, mathematical modeling has served as a simple and yet efficient tool to investigate, predict, and control spread of…

种群与进化 · 定量生物学 2020-04-10 Aresh Dadlani , Richard O. Afolabi , Hyoyoung Jung , Khosrow Sohraby , Kiseon Kim

The reconstruction of missing information in epidemic spreading on contact networks can be essential in the prevention and containment strategies. The identification and warning of infectious but asymptomatic individuals (i.e., contact…

社会与信息网络 · 计算机科学 2022-11-21 Indaco Biazzo , Alfredo Braunstein , Luca Dall'Asta , Fabio Mazza

Uncertainty can be classified as either aleatoric (intrinsic randomness) or epistemic (imperfect knowledge of parameters). The majority of frameworks assessing infectious disease risk consider only epistemic uncertainty. We only ever…

Infectious disease spread is a multi-scale process composed of within-host (biological) and between-host (social) drivers and disentangling them from each other is a central challenge in epidemiology. Here, we introduce VIBES, a multi-scale…

The paradigm for compartment models in epidemiology assumes exponentially distributed incubation and removal times, which is not realistic in actual populations. Commonly used variations with multiple exponentially distributed variables are…

种群与进化 · 定量生物学 2021-02-10 P. Hernández , C. Pena , A. Ramos , J. J. Gómez-Cadenas

Inferring how an epidemic will progress and what actions to take when presented with limited information is of critical importance for epidemiologists and health professionals. In real world settings, epidemiology data can be scarce or…

统计计算 · 统计学 2022-11-02 Georgios Efstathiadis

Protein modeling is an increasingly popular area of machine learning research. Semi-supervised learning has emerged as an important paradigm in protein modeling due to the high cost of acquiring supervised protein labels, but the current…

机器学习 · 计算机科学 2019-06-20 Roshan Rao , Nicholas Bhattacharya , Neil Thomas , Yan Duan , Xi Chen , John Canny , Pieter Abbeel , Yun S. Song

If model identifiability is not confirmed, inferences from infectious disease transmission models may not be reliable, so they might lead to misleading recommendations. Structural identifiability analysis characterizes whether it is…

定量方法 · 定量生物学 2022-06-09 Emmanuelle A. Dankwa , Andrew F. Brouwer , Christl A. Donnelly

Epidemiological models for the spread of pathogens in a population are usually only able to describe a single pathogen. This makes their application unrealistic in cases where multiple pathogens with similar symptoms are spreading…

社会与信息网络 · 计算机科学 2018-05-16 Nir Levy , Michael Iv , Elad Yom-Tov

In this paper, we study the dynamics of epidemic processes taking place in temporal and adaptive networks. Building on the activity-driven network model, we propose an adaptive model of epidemic processes, where the network topology…

社会与信息网络 · 计算机科学 2018-02-27 Masaki Ogura , Victor M. Preciado , Naoki Masuda

The COVID-19 pandemic provides new motivation for a classic problem in epidemiology: estimating the empirical rate of transmission during an outbreak (formally, the time-varying reproduction number) from case counts. While standard methods…

统计方法学 · 统计学 2020-12-08 Bryan Wilder , Michael J. Mina , Milind Tambe

Epidemic spreading of infectious diseases is ubiquitous and has often considerable impact on public health and economic wealth. The large variability in spatio-temporal patterns of epidemics prohibits simple interventions and demands for a…

种群与进化 · 定量生物学 2010-11-25 Christel Kamp

Pre-training has shown success in different areas of machine learning, such as Computer Vision (CV), Natural Language Processing (NLP) and medical imaging. However, it has not been fully explored for clinical data analysis. Even though an…

机器学习 · 计算机科学 2022-06-10 Chantal Pellegrini , Anees Kazi , Nassir Navab

Mathematical modeling of disease spreading plays a crucial role in understanding, controlling and preventing epidemic outbreaks. In a microscopic description of the propagation of a disease over the complex network of human contacts, the…

物理与社会 · 物理学 2021-10-08 Federico Malizia , Luca Gallo , Mattia Frasca , Vito Latora , Giovanni Russo

Ensemble forecasts have become a cornerstone of large-scale disease response, underpinning decision making at agencies such as the US Centers for Disease Control and Prevention (CDC). Their growing use reflects the goal of combining…

应用统计 · 统计学 2026-01-23 Carson Dudley , Marisa Eisenberg

The interplay of biological, social, structural and random factors makes disease forecasting extraordinarily complex. The course of an epidemic exhibits average growth dynamics determined by features of the pathogen and the population, yet…

种群与进化 · 定量生物学 2022-02-24 Andrea J. Allen , Mariah C. Boudreau , Nicholas J. Roberts , Antoine Allard , Laurent Hébert-Dufresne

We propose a compartmental model for epidemiology wherein the population is split into groups with either comply or refuse to comply with protocols designed to slow the spread of a disease. Parallel to the disease spread, we assume that…

动力系统 · 数学 2025-11-27 Christian Parkinson , Weinan Wang

Dynamical systems running on the top of complex networks has been extensively investigated for decades. But this topic still remains among the most relevant issues in complex network theory due to its range of applicability. The contact…

物理与社会 · 物理学 2021-02-03 Angélica S. Mata

Machine learning models must continuously self-adjust themselves for novel data distribution in the open world. As the predominant principle, entropy minimization (EM) has been proven to be a simple yet effective cornerstone in existing…

机器学习 · 统计学 2024-10-16 Qingyang Zhang , Yatao Bian , Xinke Kong , Peilin Zhao , Changqing Zhang

Mathematical modeling is one of the key factors of the effective control of newly found infectious diseases, such as COVID-19. Our knowledge about the parameters and the course of the infection is highly limited in the beginning of the…

定量方法 · 定量生物学 2021-10-13 Péter Boldog , Norbert Bogya , Zsolt Vizi