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Early fault diagnosis in complex mechanical systems such as gearbox has always been a great challenge, even with the recent development in deep neural networks. The performance of a classic fault diagnosis system predominantly depends on…

神经与进化计算 · 计算机科学 2018-10-30 Pei Cao , Shengli Zhang , Jiong Tang

Applying deep learning concepts from image detection and graph theory has greatly advanced protein-ligand binding affinity prediction, a challenge with enormous ramifications for both drug discovery and protein engineering. We build upon…

生物大分子 · 定量生物学 2023-12-05 Gregory W. Kyro , Rafael I. Brent , Victor S. Batista

Accurate prediction of drug molecule solubility is crucial for therapeutic effectiveness and safety. Traditional methods often miss complex molecular structures, leading to inaccuracies. We introduce the YZS-Model, a deep learning framework…

机器学习 · 计算机科学 2024-08-14 Chenxu Wang , Haowei Ming , Jian He , Yao Lu , Junhong Chen

The protein-ligand binding affinity (PLA) prediction goal is to predict whether or not the ligand could bind to a protein sequence. Recently, in PLA prediction, deep learning has received much attention. Two steps are involved in deep…

定量方法 · 定量生物学 2024-05-21 Karim Abbasi , Parvin Razzaghi , Amin Ghareyazi , Hamid R. Rabiee

Recent successes in image analysis with deep neural networks are achieved almost exclusively with Convolutional Neural Networks (CNNs), typically trained using the backpropagation (BP) algorithm. In a 2022 preprint, Geoffrey Hinton proposed…

计算机视觉与模式识别 · 计算机科学 2025-11-05 Riccardo Scodellaro , Ajinkya Kulkarni , Frauke Alves , Matthias Schröter

Deep convolutional neural networks have proven their effectiveness, and have been acknowledged as the most dominant method for image classification. However, a severe drawback of deep convolutional neural networks is poor explainability.…

计算机视觉与模式识别 · 计算机科学 2025-03-27 Bin Wang , Wenbin Pei , Bing Xue , Mengjie Zhang

Molecular phenotyping by gene expression profiling is common in contemporary cancer research and in molecular diagnostics. However, molecular profiling remains costly and resource intense to implement, and is just starting to be introduced…

计算机视觉与模式识别 · 计算机科学 2023-09-04 Philippe Weitz , Yinxi Wang , Kimmo Kartasalo , Lars Egevad , Johan Lindberg , Henrik Grönberg , Martin Eklund , Mattias Rantalainen

Background: Spatial transcriptomics have emerged as a powerful tool in biomedical research because of its ability to capture both the spatial contexts and abundance of the complete RNA transcript profile in organs of interest. However,…

基因组学 · 定量生物学 2025-04-18 Shuo Shuo Liu , Shikun Wang , Yuxuan Chen , Anil K. Rustgi , Ming Yuan , Jianhua Hu

Learning representations that accurately capture long-range dependencies in sequential inputs -- including text, audio, and genomic data -- is a key problem in deep learning. Feed-forward convolutional models capture only feature…

机器学习 · 计算机科学 2021-04-23 Sawyer Birnbaum , Volodymyr Kuleshov , Zayd Enam , Pang Wei Koh , Stefano Ermon

With the upcoming commensal surveys for Fast Radio Bursts (FRBs), and their high candidate rate, usage of machine learning algorithms for candidate classification is a necessity. Such algorithms will also play a pivotal role in sending…

天体物理仪器与方法 · 物理学 2020-06-26 Devansh Agarwal , Kshitij Aggarwal , Sarah Burke-Spolaor , Duncan R. Lorimer , Nathaniel Garver-Daniels

A deep feature based saliency model (DeepFeat) is developed to leverage the understanding of the prediction of human fixations. Traditional saliency models often predict the human visual attention relying on few level image cues. Although…

计算机视觉与模式识别 · 计算机科学 2017-09-11 Ali Mahdi , Jun Qin

Long-term time series forecasting is a vital task and has a wide range of real applications. Recent methods focus on capturing the underlying patterns from one single domain (e.g. the time domain or the frequency domain), and have not taken…

机器学习 · 计算机科学 2023-08-28 Yuxiao Luo , Ziyu Lyu , Xingyu Huang

This work leverages the recent advancements of deep learning in image processing to find optimal locations that present the important characteristics of a field. The data for training are collected at different fields in local farms with…

计算机视觉与模式识别 · 计算机科学 2023-09-06 Tan-Hanh Pham , Praneel Acharya , Sravanthi Bachina , Kristopher Osterloh , Kim-Doang Nguyen

Deep learning generally suffers from enormous computational resources and time-consuming training processes. Broad Learning System (BLS) and its convolutional variants have been proposed to mitigate these issues and have achieved superb…

机器学习 · 计算机科学 2023-04-04 Chunyu Lei , C. L. Philip Chen , Jifeng Guo , Tong Zhang

Effective feature interaction modeling is critical for enhancing the accuracy of click-through rate (CTR) prediction in industrial recommender systems. Most of the current deep CTR models resort to building complex network architectures to…

信息检索 · 计算机科学 2026-03-24 Honghao Li , Qiuze Ru , Yiwen Zhang , Yi Zhang , Lei Sang , Yun Yang

Visual saliency prediction using transformers - Convolutional neural networks (CNNs) have significantly advanced computational modelling for saliency prediction. However, accurately simulating the mechanisms of visual attention in the human…

多媒体 · 计算机科学 2022-06-30 Jianxun Lou , Hanhe Lin , David Marshall , Dietmar Saupe , Hantao Liu

Fingerprint recognition has been utilized for cellphone authentication, airport security and beyond. Many different features and algorithms have been proposed to improve fingerprint recognition. In this paper, we propose an end-to-end deep…

计算机视觉与模式识别 · 计算机科学 2019-07-31 Shervin Minaee , Elham Azimi , Amirali Abdolrashidi

Gene finding is the task of identifying the locations of coding sequences within the vast amount of genetic code contained in the genome. With an ever increasing quantity of raw genome sequences, gene finding is an important avenue towards…

基因组学 · 定量生物学 2025-05-07 Frederikke I. Marin , Dennis Pultz , Wouter Boomsma

Understanding non-genetic determinants of cell fate is critical for developing and improving cancer therapies, as genetically identical cells can exhibit divergent outcomes under the same treatment conditions. In this work, we present a…

计算机视觉与模式识别 · 计算机科学 2026-03-18 Florian Bürger , Martim Dias Gomes , Adrián E. Granada , Noémie Moreau , Katarzyna Bozek

Thanks to rapidly evolving sequencing techniques, the amount of genomic data at our disposal is growing increasingly large. Determining the gene structure is a fundamental requirement to effectively interpret gene function and regulation.…

基因组学 · 定量生物学 2017-11-28 Jasper Zuallaert , Mijung Kim , Yvan Saeys , Wesley De Neve