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One of the most powerful techniques to study protein structures is to look for recurrent fragments (also called substructures or spatial motifs), then use them as patterns to characterize the proteins under study. An emergent trend consists…

计算工程、金融与科学 · 计算机科学 2018-03-02 Wajdi Dhifli , Rabie Saidi , Engelbert Mephu Nguifo

Molecular "fingerprints" encoding structural information are the workhorse of cheminformatics and machine learning in drug discovery applications. However, fingerprint representations necessarily emphasize particular aspects of the…

机器学习 · 统计学 2016-08-26 Steven Kearnes , Kevin McCloskey , Marc Berndl , Vijay Pande , Patrick Riley

A wide variety of orthographic coding schemes and models of visual word identification have been developed to account for masked priming data that provide a measure of orthographic similarity between letter strings. These models tend to…

计算机视觉与模式识别 · 计算机科学 2023-03-15 Dong Yin , Valerio Biscione , Jeffrey Bowers

Modern high-resolution microscopes, such as the scanning tunneling microscope, are commonly used to study specimens that have dense and aperiodic spatial structure. Extracting meaningful information from images obtained from such…

Accelerating Magnetic Resonance Imaging (MRI) reduces scan time but often degrades image quality. While Implicit Neural Representations (INRs) show promise for MRI reconstruction, they struggle at high acceleration factors due to weak prior…

计算机视觉与模式识别 · 计算机科学 2025-08-12 Ziad Al-Haj Hemidi , Eytan Kats , Mattias P. Heinrich

Prototypical part network (ProtoPNet) methods have been designed to achieve interpretable classification by associating predictions with a set of training prototypes, which we refer to as trivial prototypes because they are trained to lie…

计算机视觉与模式识别 · 计算机科学 2023-10-24 Chong Wang , Yuyuan Liu , Yuanhong Chen , Fengbei Liu , Yu Tian , Davis J. McCarthy , Helen Frazer , Gustavo Carneiro

Diffeomorphic image registration is crucial for various medical imaging applications because it can preserve the topology of the transformation. This study introduces DCCNN-LSTM-Reg, a learning framework that evolves dynamically and learns…

图像与视频处理 · 电气工程与系统科学 2024-11-06 Jinqiu Deng , Ke Chen , Mingke Li , Daoping Zhang , Chong Chen , Alejandro F. Frangi , Jianping Zhang

While dense non-rigid structure from motion (NRSfM) has been extensively studied from the perspective of the reconstructability problem over the recent years, almost no attempts have been undertaken to bring it into the practical realm. The…

计算机视觉与模式识别 · 计算机科学 2020-07-01 Vladislav Golyanik , André Jonas , Didier Stricker , Christian Theobalt

Deep learning-based electrocardiogram (ECG) classification has shown impressive performance but clinical adoption has been slowed by the lack of transparent and faithful explanations. Post hoc methods such as saliency maps may fail to…

Many studies have concentrated on constructing supervised models utilizing paired datasets for image denoising, which proves to be expensive and time-consuming. Current self-supervised and unsupervised approaches typically rely on…

计算机视觉与模式识别 · 计算机科学 2026-03-10 Huaqiu Li , Wang Zhang , Xiaowan Hu , Tao Jiang , Zikang Chen , Haoqian Wang

Soft bodies made from flexible and deformable materials are popular in many robotics applications, but their proprioceptive sensing has been a long-standing challenge. In other words, there has hardly been a method to measure and model the…

机器人学 · 计算机科学 2019-12-09 Ruoyu Wang , Shiheng Wang , Songyu Du , Erdong Xiao , Wenzhen Yuan , Chen Feng

Recent generative models demonstrate impressive performance on synthesizing photographic images, which makes humans hardly to distinguish them from pristine ones, especially on realistic-looking synthetic facial images. Previous works…

计算机视觉与模式识别 · 计算机科学 2025-01-15 Hao Wang , Cheng Deng , Zhidong Zhao

Historical linguists have identified regularities in the process of historic sound change. The comparative method utilizes those regularities to reconstruct proto-words based on observed forms in daughter languages. Can this process be…

计算与语言 · 计算机科学 2021-05-11 Carlo Meloni , Shauli Ravfogel , Yoav Goldberg

The need for tomographic reconstruction from sparse measurements arises when the measurement process is potentially harmful, needs to be rapid, or is uneconomical. In such cases, prior information from previous longitudinal scans of the…

计算机视觉与模式识别 · 计算机科学 2018-12-31 Preeti Gopal , Sharat Chandran , Imants Svalbe , Ajit Rajwade

Establishing dense anatomical correspondence across distinct imaging modalities is a foundational yet challenging procedure for numerous medical image analysis studies and image-guided radiotherapy. Existing multi-modality image…

计算机视觉与模式识别 · 计算机科学 2024-04-02 Tony C. W. Mok , Zi Li , Yunhao Bai , Jianpeng Zhang , Wei Liu , Yan-Jie Zhou , Ke Yan , Dakai Jin , Yu Shi , Xiaoli Yin , Le Lu , Ling Zhang

A reliable prediction of 3D protein structures from sequence data remains a big challenge due to both theoretical and computational difficulties. We have previously shown that our kinetostatic compliance method (KCM) implemented into the…

计算工程、金融与科学 · 计算机科学 2017-12-27 Pouya Tavousi , Morad Behandish , Horea T. Ilies , Kazem Kazerounian

For continual learning, text-prompt-based methods leverage text encoders and learnable prompts to encode semantic features for sequentially arrived classes over time. A common challenge encountered by existing works is how to learn unique…

计算机视觉与模式识别 · 计算机科学 2026-04-02 Jie Mei , Li-Leng Peng , Keith Fuller , Jenq-Neng Hwang

Indirect image registration is a promising technique to improve image reconstruction quality by providing a shape prior for the reconstruction task. In this paper, we propose a novel hybrid method that seeks to reconstruct high quality…

图像与视频处理 · 电气工程与系统科学 2019-12-18 Jiulong Liu , Angelica I. Aviles-Rivero , Hui Ji , Carola-Bibiane Schönlieb

Image-text contrastive models such as CLIP learn transferable and robust representations for zero-shot transfer to a variety of downstream tasks. However, to obtain strong downstream performances, prompts need to be carefully curated, which…

计算机视觉与模式识别 · 计算机科学 2024-06-21 Soumya Suvra Ghosal , Samyadeep Basu , Soheil Feizi , Dinesh Manocha

While deep learning has seen many recent applications to drug discovery, most have focused on predicting activity or toxicity directly from chemical structure. Phenotypic changes exhibited in cellular images are also indications of the…

计算机视觉与模式识别 · 计算机科学 2019-03-18 Philip T. Jackson , Yinhai Wang , Sinead Knight , Hongming Chen , Thierry Dorval , Martin Brown , Claus Bendtsen , Boguslaw Obara