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Large Language Models (LLMs) have revolutionized various sectors, including healthcare where they are employed in diverse applications. Their utility is particularly significant in the context of rare diseases, where data scarcity,…

计算与语言 · 计算机科学 2024-08-20 Qiuhao Lu , Rui Li , Andrew Wen , Jinlian Wang , Liwei Wang , Hongfang Liu

Large language models (LLMs) have immense potential to make information more accessible, particularly in medicine, where complex medical jargon can hinder patient comprehension of clinical notes. We developed a patient-facing tool using…

The ability of large language models (LLMs) to follow natural language instructions with human-level fluency suggests many opportunities in healthcare to reduce administrative burden and improve quality of care. However, evaluating LLMs on…

The digitalization of stored information in hospitals now allows for the exploitation of medical data in text format, as electronic health records (EHRs), initially gathered for other purposes than epidemiology. Manual search and analysis…

The reliability of clinical artificial intelligence (AI) depends on high-quality data, yet Electronic Health Records are often inconsistent with existing scientific knowledge. Current quality assessments are limited: they either focus on…

机器学习 · 计算机科学 2026-05-26 Irena Girshovitz , Atai Ambus , Moni Shahar , Ran Gilad-Bachrach

Generative models can produce synthetic patient records for analytical tasks when real data is unavailable or limited. However, current methods struggle with adhering to domain-specific knowledge and removing invalid data. We present…

机器学习 · 计算机科学 2023-12-22 Brandon Theodorou , Shrusti Jain , Cao Xiao , Jimeng Sun

The application of Artificial Intelligence (AI) in healthcare has been revolutionary, especially with the recent advancements in transformer-based Large Language Models (LLMs). However, the task of understanding unstructured electronic…

计算与语言 · 计算机科学 2023-08-08 Shivani Shekhar , Simran Tiwari , T. C. Rensink , Ramy Eskander , Wael Salloum

Access to high-quality medical data is often restricted due to privacy concerns, posing significant challenges for training artificial intelligence (AI) algorithms within Electronic Health Record (EHR) applications. In this study, prompt…

人工智能 · 计算机科学 2025-04-30 Polycarp Nalela

Electronic health records (EHRs) are invaluable for clinical research, yet privacy concerns severely restrict data sharing. Synthetic data generation offers a promising solution, but EHRs present unique challenges: they contain both…

机器学习 · 计算机科学 2026-03-26 Shaonan Liu , Yuichiro Iwashita , Soichiro Nakako , Masakazu Iwamura , Koichi Kise

This paper explores the use of large language models (LLMs) to assist in the development of new disease modules for Synthea, an open-source synthetic health data generator. Incorporating LLMs into the module development process has the…

人工智能 · 计算机科学 2025-07-30 Mark A. Kramer , Aanchal Mathur , Caroline E. Adams , Jason A. Walonoski

Electronic health records (EHRs) are central to modern healthcare delivery and research; yet, many researchers lack the database expertise necessary to write complex SQL queries or generate effective visualizations, limiting efficient data…

Deep learning models exhibit state-of-the-art performance for many predictive healthcare tasks using electronic health records (EHR) data, but these models typically require training data volume that exceeds the capacity of most healthcare…

机器学习 · 计算机科学 2018-10-24 Edward Choi , Cao Xiao , Walter F. Stewart , Jimeng Sun

With the rapid development of large language models (LLMs), more and more researchers have paid attention to information extraction based on LLMs. However, there are still some spaces to improve in the existing related methods. First,…

计算与语言 · 计算机科学 2026-03-24 Jiang Liu , Ge Qiu , Hao Fei , Dongdong Xie , Jinbo Li , Fei Li , Chong Teng , Donghong Ji

Constructing large-scaled medical knowledge graphs can significantly boost healthcare applications for medical surveillance, bring much attention from recent research. An essential step in constructing large-scale MKG is extracting…

计算机视觉与模式识别 · 计算机科学 2021-10-27 Jialun Wu , Yang Liu , Zeyu Gao , Tieliang Gong , Chunbao Wang , Chen Li

Extracting structured information from clinical notes requires navigating a dense web of interdependent variables where the value of one attribute logically constrains others. Existing Large Language Model (LLM)-based extraction pipelines…

Large language models (LLMs) integrated into agent-driven workflows hold immense promise for healthcare, yet a significant gap exists between their potential and practical implementation within clinical settings. To address this, we present…

Mining Electronic Health Records (EHRs) becomes a promising topic because of the rich information they contain. By learning from EHRs, machine learning models can be built to help human experts to make medical decisions and thus improve…

机器学习 · 计算机科学 2021-01-19 Zheng Liu , Xiaohan Li , Hao Peng , Lifang He , Philip S. Yu

Electronic Health Record (EHR) retrieval plays a pivotal role in various clinical tasks, but its development has been severely impeded by the lack of publicly available benchmarks. In this paper, we introduce a novel public EHR retrieval…

信息检索 · 计算机科学 2025-04-09 Zhengyun Zhao , Hongyi Yuan , Jingjing Liu , Haichao Chen , Huaiyuan Ying , Songchi Zhou , Yue Zhong , Sheng Yu

Seeking dietary guidance often requires navigating complex professional knowledge while accommodating individual health conditions. Knowledge Graphs (KGs) offer structured and interpretable nutritional information, whereas Large Language…

人机交互 · 计算机科学 2025-04-22 Fan Gao , Xinjie Zhao , Ding Xia , Zhongyi Zhou , Rui Yang , Jinghui Lu , Hang Jiang , Chanjun Park , Irene Li

Retrieving information from EHR systems is essential for answering specific questions about patient journeys and improving the delivery of clinical care. Despite this fact, most EHR systems still rely on keyword-based searches. With the…

计算与语言 · 计算机科学 2024-04-11 Shashi Kant Gupta , Aditya Basu , Bradley Taylor , Anai Kothari , Hrituraj Singh