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With the growing interest in foundation models for brain signals, graph-based pretraining has emerged as a promising paradigm for learning transferable representations from connectome data. However, existing contrastive and masked…

机器学习 · 计算机科学 2026-03-10 Xinxu Wei , Rong Zhou , Lifang He , Yu Zhang

To evaluate the translational capabilities of foundation models, we develop a pathological concept learning approach focused on kidney cancer. By leveraging TNM staging guidelines and pathology reports, we build comprehensive pathological…

Computational pathology has made significant progress in recent years, fueling advances in both fundamental disease understanding and clinically ready tools. This evolution is driven by the availability of large amounts of digitized slides…

Representation learning of pathology whole-slide images (WSIs) has been has primarily relied on weak supervision with Multiple Instance Learning (MIL). However, the slide representations resulting from this approach are highly tailored to…

计算机视觉与模式识别 · 计算机科学 2024-05-21 Andrew H. Song , Richard J. Chen , Tong Ding , Drew F. K. Williamson , Guillaume Jaume , Faisal Mahmood

Pathology foundation models (PFMs) have emerged as a core approach for learning transferable representations from whole slide images (WSIs), and they are typically benchmarked through downstream clinical endpoints. While such task level…

计算机视觉与模式识别 · 计算机科学 2026-05-26 Bokai Zhao , Yiyang Zhang , Yuanchi Zhu , Hanqing Chao , Long Bai , Tai Ma , Minfeng Xu , Ming Song , Tianzi Jiang

Pathology foundation models (PFMs) have emerged as powerful pretrained encoders for computational pathology, but their robustness under clinically relevant distribution shifts remains insufficiently understood. We benchmark the robustness…

图像与视频处理 · 电气工程与系统科学 2026-04-29 Fredrik K. Gustafsson , Mattias Rantalainen

Computational pathology needs whole-slide image (WSI) foundation models that transfer across diverse clinical tasks, yet current approaches remain largely slide-centric, often depend on private data and expensive paired-report supervision,…

计算机视觉与模式识别 · 计算机科学 2026-04-02 Yousef Kotp , Vincent Quoc-Huy Trinh , Christopher Pal , Mahdi S. Hosseini

Deep learning methods are widely applied in digital pathology to address clinical challenges such as prognosis and diagnosis. As one of the most recent applications, deep models have also been used to extract molecular features from whole…

图像与视频处理 · 电气工程与系统科学 2022-03-29 Amir Safarpoor , Jason D. Hipp , H. R. Tizhoosh

The advent of large-scale self-supervised learning (SSL) has produced a vast zoo of medical foundation models. However, selecting optimal medical foundation models for specific segmentation tasks remains a computational bottleneck. Existing…

计算机视觉与模式识别 · 计算机科学 2026-05-26 Jiaqi Tang , Shaoyang Zhang , Xiaoqi Wang , Jiaying Zhou , Yang Liu , Qingchao Chen

Advances in foundation modeling have reshaped computational pathology. However, the increasing number of available models and lack of standardized benchmarks make it increasingly complex to assess their strengths, limitations, and potential…

计算机视觉与模式识别 · 计算机科学 2025-02-11 Andrew Zhang , Guillaume Jaume , Anurag Vaidya , Tong Ding , Faisal Mahmood

The emergence of foundation models in computational pathology has transformed histopathological image analysis, with whole slide imaging (WSI) diagnosis being a core application. Traditionally, weakly supervised fine-tuning via multiple…

计算机视觉与模式识别 · 计算机科学 2025-03-03 Jiawen Li , Jiali Hu , Qiehe Sun , Renao Yan , Minxi Ouyang , Tian Guan , Anjia Han , Chao He , Yonghong He

Vision foundation models (FMs) are accelerating the development of digital pathology algorithms and transforming biomedical research. These models learn, in a self-supervised manner, to represent histological features in highly…

Pathology has played a crucial role in the diagnosis and evaluation of patient tissue samples obtained from surgeries and biopsies for many years. The advent of Whole Slide Scanners and the development of deep learning technologies have…

计算机视觉与模式识别 · 计算机科学 2024-08-07 Mieko Ochi , Daisuke Komura , Shumpei Ishikawa

Computational pathology foundation models (CPathFMs) have emerged as a powerful approach for analyzing histopathological data, leveraging self-supervised learning to extract robust feature representations from unlabeled whole-slide images.…

计算机视觉与模式识别 · 计算机科学 2025-02-27 Dong Li , Guihong Wan , Xintao Wu , Xinyu Wu , Ajit J. Nirmal , Christine G. Lian , Peter K. Sorger , Yevgeniy R. Semenov , Chen Zhao

Tissue phenotyping is a fundamental computational pathology (CPath) task in learning objective characterizations of histopathologic biomarkers in anatomic pathology. However, whole-slide imaging (WSI) poses a complex computer vision problem…

Pathology foundation models (PFMs) have emerged as powerful tools for analyzing whole slide images (WSIs). However, adapting these pretrained PFMs for specific clinical tasks presents considerable challenges, primarily due to the…

Deep Learning-based computational pathology algorithms have demonstrated profound ability to excel in a wide array of tasks that range from characterization of well known morphological phenotypes to predicting non-human-identifiable…

图像与视频处理 · 电气工程与系统科学 2020-09-24 Ming Y. Lu , Dehan Kong , Jana Lipkova , Richard J. Chen , Rajendra Singh , Drew F. K. Williamson , Tiffany Y. Chen , Faisal Mahmood

Accurate diagnosis and treatment of complex diseases require integrating histological, molecular, and clinical data, yet in practice these modalities are often incomplete owing to tissue scarcity, assay cost, and workflow constraints.…

计算机视觉与模式识别 · 计算机科学 2026-04-07 Jinxi Xiang , Mingjie Li , Siyu Hou , Yijiang Chen , Xiangde Luo , Yuanfeng Ji , Xiang Zhou , Ehsan Adeli , Akshay Chaudhari , Curtis P. Langlotz , Kilian M. Pohl , Ruijiang Li