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相关论文: Distinguishing Parkinson's Patients Using Voice-Ba…

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Parkinson's disease (PD) is a highly heterogeneous disease, including which motor symptoms are dominating. Imaging biomarkers that support subtype stratification could also improve biological understanding and study design, and enable…

We investigate the potential association between leucine-rich repeat kinase 2 (LRRK2) mutations and voice. Sustained phonations ('aaah' sounds) were recorded from 7 individuals with LRRK2-associated Parkinson's disease (PD), 17 participants…

Background: Parkinson's disease remains a major neurodegenerative disorder with high misdiagnosis rates, primarily due to reliance on clinical rating scales. Recent studies have demonstrated a strong association between gut microbiota and…

人工智能 · 计算机科学 2025-09-10 Bo Yu , Zhixiu Hua , Bo Zhao

Deep learning holds tremendous potential in healthcare for uncovering hidden patterns within extensive clinical datasets, aiding in the diagnosis of various diseases. Parkinson's disease (PD) is a neurodegenerative condition characterized…

计算机视觉与模式识别 · 计算机科学 2024-12-10 Aqib Nazir Mir , Iqra Nissar , Mumtaz Ahmed , Sarfaraz Masood , Danish Raza Rizvi

Parkinson's Disease (PD) is a degenerative neurological disorder that impairs motor and non-motor functions, significantly reducing quality of life and increasing mortality risk. Early and accurate detection of PD progression is vital for…

机器学习 · 计算机科学 2024-12-31 Abhinav Roy , Bhavesh Gyanchandani , Aditya Oza , Abhishek Sharma

In recent years, applications of data mining methods are become more popular in many fields of medical diagnosis and evaluations. The data mining methods are appropriate tools for discovering and extracting of available knowledge in medical…

计算工程、金融与科学 · 计算机科学 2013-12-10 Peyman Mohammadi , Abdolreza Hatamlou , Mohammad Masdari

Diagnosing autism spectrum disorder (ASD) by identifying abnormal speech patterns from examiner-patient dialogues presents significant challenges due to the subtle and diverse manifestations of speech-related symptoms in affected…

声音 · 计算机科学 2024-05-09 Chuanbo Hu , Jacob Thrasher , Wenqi Li , Mindi Ruan , Xiangxu Yu , Lynn K Paul , Shuo Wang , Xin Li

The stage and severity of Parkinson's disease (PD) is an important factor to consider for taking effective therapeutic decisions. Although the Movement Disorder Society-Unified Parkinson's Disease Rating Scale (MDS-UPDRS) provides an…

应用统计 · 统计学 2018-05-30 R. Prashanth , Sumantra Dutta Roy

Parkinson's disease (PD) belongs to the class of neurodegenerative disorders that affect the central nervous system. It is usually defined as the gradual loss of dopaminergic neurons in the substantia nigra pars compacta, which causes both…

神经元与认知 · 定量生物学 2024-11-01 Hina Shaheen , Roderick Melnik

Accurately quantifying motor characteristics in Parkinson disease (PD) is crucial for monitoring disease progression and optimizing treatment strategies. The finger-tapping test is a standard motor assessment. Clinicians visually evaluate a…

计算机视觉与模式识别 · 计算机科学 2025-11-14 Tahereh Zarrat Ehsan , Michael Tangermann , Yağmur Güçlütürk , Bastiaan R. Bloem , Luc J. W. Evers

The potential of speech as a non-invasive biomarker to assess a speaker's health has been repeatedly supported by the results of multiple works, for both physical and psychological conditions. Traditional systems for speech-based disease…

音频与语音处理 · 电气工程与系统科学 2020-06-02 Catarina Botelho , Francisco Teixeira , Thomas Rolland , Alberto Abad , Isabel Trancoso

Parkinson's Disease (PD) is one of the most common types of neurological diseases caused by progressive degeneration of dopamin- ergic neurons in the brain. Even though there is no fixed cure for this neurodegenerative disease, earlier…

计算机视觉与模式识别 · 计算机科学 2018-06-21 Sara Soltaninejad , Irene Cheng , Anup Basu

The rapid emergence of highly adaptable and reusable artificial intelligence (AI) models is set to revolutionize the medical field, particularly in the diagnosis and management of Parkinson's disease (PD). Currently, there are no effective…

机器学习 · 计算机科学 2025-02-18 Aite Zhao , Yongcan Liu , Xinglin Yu , Xinyue Xing

Parkinson's disease (PD) is a debilitating neurodegenerative disease that has severe impacts on an individual's quality of life. Compared with structural and functional MRI-based biomarkers for the disease, electroencephalography (EEG) can…

机器学习 · 计算机科学 2024-08-05 Christopher Neves , Yong Zeng , Yiming Xiao

One major challenge in the medication of Parkinson's disease is that the severity of the disease, reflected in the patients' motor state, cannot be measured using accessible biomarkers. Therefore, we develop and examine a variety of…

机器学习 · 计算机科学 2019-04-26 Jann Goschenhofer , Franz MJ Pfister , Kamer Ali Yuksel , Bernd Bischl , Urban Fietzek , Janek Thomas

This work aims to tackle the Parkinson's disease (PD) detection problem from the speech signal in a bilingual setting by proposing an ad-hoc dual-head deep neural architecture for type-based binary classification. One head is specialized…

音频与语音处理 · 电气工程与系统科学 2025-11-13 Moreno La Quatra , Juan Rafael Orozco-Arroyave , Marco Sabato Siniscalchi

Motor dysfunction is a common sign of neurodegenerative diseases (NDs) such as Parkinson's disease (PD) and Alzheimer's disease (AD), but may be difficult to detect, especially in the early stages. In this work, we examine the behavior of a…

神经元与认知 · 定量生物学 2025-10-23 Thomas Thebaud , Anna Favaro , Casey Chen , Gabrielle Chavez , Laureano Moro-Velazquez , Ankur Butala , Najim Dehak

A transversal study of the pitch variability of parkinsonian voices in read speech is presented. 30 patients suffering from Parkinson's disease (PD) and 32 healthy speakers were recorded while reading a text without voiceless phonemes. The…

音频与语音处理 · 电气工程与系统科学 2024-02-12 Pablo Rodriguez-Perez , Ruben Fraile , Miguel Garcia-Escrig , Nicolas Saenz-Lechon , Juana M. Gutierrez-Arriola , Victor Osma-Ruiz

Parkinsons Disease is a neurological disorder and prevalent in elderly people. Traditional ways to diagnose the disease rely on in-person subjective clinical evaluations on the quality of a set of activity tests. The high-resolution…

机器学习 · 计算机科学 2020-10-16 Weijian Li , Wei Zhu , E. Ray Dorsey , Jiebo Luo

Dementia is a syndrome, generally of a chronic nature characterized by a deterioration in cognitive function, especially in the geriatric population and is severe enough to impact their daily activities. Early diagnosis of dementia is…

音频与语音处理 · 电气工程与系统科学 2020-07-21 Rupayan Chakraborty , Meghna Pandharipande , Chitralekha Bhat , Sunil Kumar Kopparapu