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Parkinson's disease is a neurological condition that occurs in nearly 1% of the world's population. The disease is manifested by a drop in dopamine production, symptoms are cognitive and behavioural and include a wide range of personality…
The global prevalence of dementia is projected to double by 2050, highlighting the urgent need for scalable diagnostic tools. This study utilizes digital cognitive tasks with eye-tracking data correlated with memory processes to distinguish…
Purpose: Optical Coherence Tomography Angiography (OCT-A) permits visualization of the changes to the retinal circulation due to diabetic retinopathy (DR), a microvascular complication of diabetes. We demonstrate accurate segmentation of…
Retinal degenerative diseases cause profound visual impairment in more than 10 million people worldwide, and retinal prostheses are being developed to restore vision to these individuals. Analogous to cochlear implants, these devices…
Diabetic Retinopathy is a global health problem, influences 100 million individuals worldwide, and in the next few decades, these incidences are expected to reach epidemic proportions. Diabetic Retinopathy is a subtle eye disease that can…
Migraine, a prevalent neurological disorder, has been associated with various ocular manifestations suggestive of neuronal and microvascular deficits. However, there is limited understanding of the extent to which retinal imaging may…
Diabetic Retinopathy (DR) is a leading cause of vision loss worldwide, requiring early detection to preserve sight. Limited access to physicians often leaves DR undiagnosed. To address this, AI models utilize lesion segmentation for…
Diabetic Retinopathy (DR) is a severe complication that may lead to retinal vascular damage and is one of the leading causes of vision impairment and blindness. DR broadly is classified into two stages - non-proliferative (NPDR), where…
Diabetic Retinopathy (DR) caused by diabetes occurs as a result of changes in the retinal vessels and causes visual impairment. Microaneurysms (MAs) are the early clinical signs of DR, whose timely diagnosis can help detecting DR in the…
Orofacial deficits are common in people with Parkinson's disease (PD) and their evolution might represent an important biomarker of disease progression. We are developing an automated system for assessment of orofacial function in PD that…
Early diagnosis of retinal diseases such as diabetic retinopathy has had the attention of many researchers. Deep learning through the introduction of convolutional neural networks has become a prominent solution for image-related tasks such…
Non-destructive testing (NDT) is essential in ceramic manufacturing to ensure the quality of components without compromising their integrity. In this context, Optical Coherence Tomography (OCT) enables high-resolution internal imaging,…
Retinal optical coherence tomography (OCT) and optical coherence tomography angiography (OCTA) are promising tools for the (early) diagnosis of Alzheimer's disease (AD). These non-invasive imaging techniques are cost-effective and more…
Optical Coherence Tomography Angiography (OCTA) is a non-invasive and non-contacting imaging technique providing visualization of microvasculature of retina and optic nerve head in human eyes in vivo. The adequate image quality of OCTA is…
Modern biomedical image analysis using deep learning often encounters the challenge of limited annotated data. To overcome this issue, deep generative models can be employed to synthesize realistic biomedical images. In this regard, we…
Age-related macular degeneration (AMD) is a major cause of blindness in older adults, severely affecting vision and quality of life. Despite advances in understanding AMD, the molecular factors driving the severity of subretinal scarring…
Parkinson's Disease (PD) is a neurodegenerative disease that currently does not have a cure. In order to facilitate disease management and reduce the speed of symptom progression, early diagnosis is essential. The current clinical,…
Purpose: To assess whether a generative adversarial network (GAN) could synthesize realistic optical coherence tomography (OCT) images that satisfactorily serve as the educational images for retinal specialists and the training datasets for…
Abnormalities in retinal fundus images may indicate certain pathologies such as diabetic retinopathy, hypertension, stroke, glaucoma, retinal macular edema, venous occlusion, and atherosclerosis, making the study and analysis of retinal…
We present a cascade deep neural network to segment retinal vessels in volumetric optical coherence tomography (OCT). Two types of knowledge are infused into the network for confining the searching regions. (1) Histology. The retinal…