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Alzheimer's Disease (AD) is an irreversible neurodegenerative disease characterized by progressive cognitive decline as its main symptom. In the research field of deep learning-assisted diagnosis of AD, traditional convolutional neural…

图像与视频处理 · 电气工程与系统科学 2025-07-15 Yang Ming , Jiang Shi Zhong , Zhou Su Juan

The prediction of mild cognitive impairment (MCI) conversion to Alzheimer's disease (AD) is important for early treatment to prevent or slow the progression of AD. To accurately predict the MCI conversion to stable MCI or progressive MCI,…

计算机视觉与模式识别 · 计算机科学 2023-07-17 Linfeng Liu , Junyan Lyu , Siyu Liu , Xiaoying Tang , Shekhar S. Chandra , Fatima A. Nasrallah

Alzheimer's Disease (AD) is a complex neurodegenerative disorder marked by memory loss, executive dysfunction, and personality changes. Early diagnosis is challenging due to subtle symptoms and varied presentations, often leading to…

计算机视觉与模式识别 · 计算机科学 2025-01-06 Yifei Chen , Shenghao Zhu , Zhaojie Fang , Chang Liu , Binfeng Zou , Yuhe Wang , Shuo Chang , Fan Jia , Feiwei Qin , Jin Fan , Yong Peng , Changmiao Wang

Alzheimer's Disease (AD) is a progressive neurodegenerative disease. Amnestic mild cognitive impairment (MCI) is a common first symptom before the conversion to clinical impairment where the individual becomes unable to perform activities…

计算机视觉与模式识别 · 计算机科学 2017-10-16 Donghuan Lu , Karteek Popuri , Weiguang Ding , Rakesh Balachandar , Mirza Faisal Beg

Accurate medical classification requires a large number of multi-modal data, and in many cases, different feature types. Previous studies have shown promising results when using multi-modal data, outperforming single-modality models when…

图像与视频处理 · 电气工程与系统科学 2023-07-21 Linfeng Liu , Siyu Liu , Lu Zhang , Xuan Vinh To , Fatima Nasrallah , Shekhar S. Chandra

Alzheimer's Disease (AD) is the most common neurodegenerative disorder with one of the most complex pathogeneses, making effective and clinically actionable decision support difficult. The objective of this study was to develop a novel…

机器学习 · 计算机科学 2022-09-27 Michal Golovanevsky , Carsten Eickhoff , Ritambhara Singh

Accurate prediction of conversion from Mild Cognitive Impairment (MCI) to Alzheimers Diseases (AD) is essential for early intervention, however, developing reliable conversion predictive models is difficult to develop due to limited…

Alzheimer's disease (AD) is the most common age-related dementia. Mild cognitive impairment (MCI) is the early stage of cognitive decline before AD. It is crucial to predict the MCI-to-AD conversion for precise management, which remains…

图像与视频处理 · 电气工程与系统科学 2022-03-10 Yiran Wei , Stephen J. Price , Carola-Bibiane Schönlieb , Chao Li

Alzheimer's disease is a progressive neurological disorder characterized by cognitive impairment and memory loss. With the increasing aging population, the incidence of AD is continuously rising, making early diagnosis and intervention an…

图像与视频处理 · 电气工程与系统科学 2023-11-23 Guian Fang , Mengsha Liu , Yi Zhong , Zhuolin Zhang , Jiehui Huang , Zhenchao Tang , Calvin Yu-Chian Chen

Alzheimer's disease (AD) is a prevalent neurodegenerative disorder that progressively impairs memory, decision-making, and overall cognitive function. As AD is irreversible, early prediction is critical for timely intervention and…

计算机视觉与模式识别 · 计算机科学 2025-12-01 Mahdieh Behjat Khatooni , Mohsen Soryani

The accurate diagnosis of Alzheimer's disease (AD) and prognosis of mild cognitive impairment (MCI) conversion are crucial for early intervention. However, existing multimodal methods face several challenges, from the heterogeneity of input…

机器学习 · 计算机科学 2025-03-20 Chenyu Liu , Luca Rossi

\textbf{Objective:} Alzheimer's disease (AD) is the most prevalent form of dementia worldwide, encompassing a prodromal stage known as Mild Cognitive Impairment (MCI), where patients may either progress to AD or remain stable. The objective…

Recent advancements in the acquisition of various brain data sources have created new opportunities for integrating multimodal brain data to assist in early detection of complex brain disorders. However, current data integration approaches…

图像与视频处理 · 电气工程与系统科学 2023-05-26 Reza Shirkavand , Liang Zhan , Heng Huang , Li Shen , Paul M. Thompson

Predicting whether subjects with mild cognitive impairment (MCI) will convert to Alzheimer's disease is a significant clinical challenge. Longitudinal variations and complementary information inherent in longitudinal and multimodal data are…

图像与视频处理 · 电气工程与系统科学 2023-05-26 Tao Wang , Xiumei Chen , Xiaoling Zhang , Shuoling Zhou , Qianjin Feng , Meiyan Huang

Predicting conversion from Mild Cognitive Impairment (MCI) to Alzheimer's Disease (AD) is critical for early intervention. Current deep learning paradigms predominantly rely on cross-sectional structural MRI, neglecting prognostic value in…

计算机视觉与模式识别 · 计算机科学 2026-05-28 Alireza Moayedikia , Sara Fin , Alicia Troncoso Lora , Uffe Kock Wiil

The assessment of Alzheimer's Disease (AD) and Mild Cognitive Impairment (MCI) associated with brain changes remains a challenging task. Recent studies have demonstrated that combination of multi-modality imaging techniques can better…

机器学习 · 计算机科学 2022-09-26 Jun Yu , Zhaoming Kong , Liang Zhan , Li Shen , Lifang He

Alzheimer's disease (AD) progression follows a complex continuum from normal cognition (NC) through mild cognitive impairment (MCI) to dementia, yet most deep learning approaches oversimplify this into discrete classification tasks. This…

图像与视频处理 · 电气工程与系统科学 2025-08-05 Yufeng Jiang , Hexiao Ding , Hongzhao Chen , Jing Lan , Xinzhi Teng , Gerald W. Y. Cheng , Zongxi Li , Haoran Xie , Jung Sun Yoo , Jing Cai

Alzheimer's disease (AD) is the most prevalent form of dementia, and its early diagnosis is essential for slowing disease progression. Recent studies on multimodal neuroimaging fusion using MRI and PET have achieved promising results by…

计算机视觉与模式识别 · 计算机科学 2025-11-05 Delin Ma , Menghui Zhou , Jun Qi , Yun Yang , Po Yang

Fusing structural-functional images of the brain has shown great potential to analyze the deterioration of Alzheimer's disease (AD). However, it is a big challenge to effectively fuse the correlated and complementary information from…

图像与视频处理 · 电气工程与系统科学 2023-10-06 Qiankun Zuo , Junren Pan , Shuqiang Wang

The early detection of Alzheimer's Disease is imperative to ensure early treatment and improve patient outcomes. There has consequently been extenstive research into detecting AD and its intermediate phase, mild cognitive impairment (MCI).…

图像与视频处理 · 电气工程与系统科学 2024-01-17 Jamie Vo , Naeha Sharif , Ghulam Mubashar Hassan
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