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The specificty and sensitivity of resting state functional MRI (rs-fMRI) measurements depend on pre-processing choices, such as the parcellation scheme used to define regions of interest (ROIs). In this study, we critically evaluate the…

计算机视觉与模式识别 · 计算机科学 2019-06-06 Meenakshi Khosla , Keith Jamison , Amy Kuceyeski , Mert R. Sabuncu

While unsupervised variational autoencoders (VAE) have become a powerful tool in neuroimage analysis, their application to supervised learning is under-explored. We aim to close this gap by proposing a unified probabilistic model for…

机器学习 · 计算机科学 2019-07-15 Qingyu Zhao , Ehsan Adeli , Nicolas Honnorat , Tuo Leng , Kilian M. Pohl

Purpose: To develop an age prediction model which is interpretable and robust to demographic and technological variances in brain MRI scans. Materials and Methods: We propose a transformer-based architecture that leverages self-supervised…

计算机视觉与模式识别 · 计算机科学 2025-06-24 Pengyu Kan , Craig Jones , Kenichi Oishi

Numerous studies have established that estimated brain age, as derived from statistical models trained on healthy populations, constitutes a valuable biomarker that is predictive of cognitive decline and various neurological diseases. In…

计算机视觉与模式识别 · 计算机科学 2019-07-02 Xinyang Feng , Zachary C. Lipton , Jie Yang , Scott A. Small , Frank A. Provenzano

The ability to determine if the brain is developing normally is a key component of pediatric neuroradiology and neurology. Brain magnetic resonance imaging (MRI) of infants demonstrates a specific pattern of development beyond simply…

图像与视频处理 · 电气工程与系统科学 2020-10-09 M. Shabanian , A. Siddiqui , H. Chen , J. P. DeVincenzo

Data produced by resting-state functional Magnetic Resonance Imaging are widely used to infer brain functional connectivity networks. Such networks correlate neural signals to connect brain regions, which consist in groups of dependent…

统计方法学 · 统计学 2023-12-05 Hanâ Lbath , Alexander Petersen , Sophie Achard

MRI-based brain age estimation models aim to assess a subject's biological brain age based on information, such as neuroanatomical features. Various factors, including neurodegenerative diseases, can accelerate brain aging and measuring…

计算机视觉与模式识别 · 计算机科学 2025-12-01 Simon Joseph Clément Crête , Marta Kersten-Oertel , Yiming Xiao

Brain age estimation from Magnetic Resonance Images (MRI) derives the difference between a subject's biological brain age and their chronological age. This is a potential biomarker for neurodegeneration, e.g. as part of Alzheimer's disease.…

计算机视觉与模式识别 · 计算机科学 2020-10-02 Kyriaki-Margarita Bintsi , Vasileios Baltatzis , Arinbjörn Kolbeinsson , Alexander Hammers , Daniel Rueckert

Brain age prediction based on neuroimaging data could help characterize both the typical brain development and neuropsychiatric disorders. Pattern recognition models built upon functional connectivity (FC) measures derived from resting…

计算机视觉与模式识别 · 计算机科学 2018-01-15 Hongming Li , Theodore D. Satterthwaite , Yong Fan

The study of healthy brain development helps to better understand the brain transformation and brain connectivity patterns which happen during childhood to adulthood. This study presents a sparse machine learning solution across whole-brain…

机器学习 · 计算机科学 2019-04-03 Peyman Hosseinzadeh Kassani , Alexej Gossmann , Yu-Ping Wang

Brain decoding that classifies cognitive states using the functional fluctuations of the brain can provide insightful information for understanding the brain mechanisms of cognitive functions. Among the common procedures of decoding the…

人机交互 · 计算机科学 2024-07-12 Jianfei Zhu , Baichun Wei , Jiaru Tian , Feng Jiang , Chunzhi Yi

In recent years, deep learning has rapidly become a method of choice for the segmentation of medical images. Deep Neural Network (DNN) architectures such as UNet have achieved state-of-the-art results on many medical datasets. To further…

计算机视觉与模式识别 · 计算机科学 2021-04-13 Truong Dang , Tien Thanh Nguyen , John McCall , Eyad Elyan , Carlos Francisco Moreno-García

The concept of biological age (BA), although important in clinical practice, is hard to grasp mainly due to the lack of a clearly defined reference standard. For specific applications, especially in pediatrics, medical image data are used…

图像与视频处理 · 电气工程与系统科学 2021-03-22 Karim Armanious , Sherif Abdulatif , Wenbin Shi , Shashank Salian , Thomas Küstner , Daniel Weiskopf , Tobias Hepp , Sergios Gatidis , Bin Yang

Ensemble learning remains a cornerstone of machine learning, with stacking used to integrate predictions from multiple base learners through a meta-model. However, deep stacking remains uncommon due to feature redundancy, complexity, and…

机器学习 · 计算机科学 2026-03-03 Çağatay Demirel

Brain Age (BA) estimation via Deep Learning has become a strong and reliable bio-marker for brain health, but the black-box nature of Neural Networks does not easily allow insight into the features of brain ageing.We trained a ResNet model…

神经元与认知 · 定量生物学 2022-07-26 Daniel Taylor , Jonathan Shock , Deshendran Moodley , Jonathan Ipser , Matthias Treder

Accurate estimation of biological brain age from three dimensional (3D) T$_1$-weighted magnetic resonance imaging (MRI) is a critical imaging biomarker for identifying accelerated aging associated with neurodegenerative diseases. Effective…

图像与视频处理 · 电气工程与系统科学 2025-08-05 Mehreen Kanwal , Yunsik Son

Ensemble learning use multiple algorithms to obtain better predictive performance than any single one of its constituent algorithms could. With growing popularity of deep learning, researchers have started to ensemble them for various…

机器学习 · 计算机科学 2019-05-31 Ning An , Huitong Ding , Jiaoyun Yang , Rhoda Au , Ting Fang Alvin Ang

Resting-state fMRI captures spontaneous neural activity characterized by complex spatiotemporal dynamics. Various metrics, such as local and global brain connectivity and low-frequency amplitude fluctuations, quantify distinct aspects of…

神经元与认知 · 定量生物学 2025-05-13 Simon Wein , Marco Riebel , Lisa-Marie Brunner , Caroline Nothdurfter , Rainer Rupprecht , Jens V. Schwarzbach

Multi-subject functional magnetic resonance imaging (fMRI) data has been increasingly used to study the population-wide relationship between human brain activity and individual biological or behavioral traits. A common method is to regress…

应用统计 · 统计学 2015-09-15 Fan Li , Tingting Zhang , Quanli Wang , Marlen Z. Gonzalez , Erin L. Maresh , James A. Coan

Bone age is an important measure for assessing the skeletal and biological maturity of children. Delayed or increased bone age is a serious concern for pediatricians, and needs to be accurately assessed in a bid to determine whether bone…

计算机视觉与模式识别 · 计算机科学 2021-04-19 Ibrahim Salim , A. Ben Hamza