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Virtual interventions enable the physics-based simulation of device deployment within coronary arteries. This framework allows for counterfactual reasoning by deploying the same device in different arterial anatomies. However, current…

图像与视频处理 · 电气工程与系统科学 2025-11-26 Karim Kadry , Shreya Gupta , Jonas Sogbadji , Michiel Schaap , Kersten Petersen , Takuya Mizukami , Carlos Collet , Farhad R. Nezami , Elazer R. Edelman

Numerical simulations of real-world phenomena require a computational scheme and a computational domain. In the context of haemodynamics, the computational domain is the blood vessel network through which blood flows. Such networks contain…

离散数学 · 计算机科学 2025-02-19 Jay Aodh Mackenzie , Megan Jeanne Miller , Nicholas Hill , Mette Olufsen

The simulation of blood flow and pressure in arteries requires outflow boundary conditions that incorporate models of downstream domains. We previously described a coupled multidomain method to couple analytical models of the downstream…

医学物理 · 物理学 2020-07-17 Irene Vignon-Clementel , C. A. Figueroa , K. E. Jansen , C. A. Taylor

Fractional flow reserve (FFR) is the gold standard for diagnosing coronary artery disease (CAD). FFRCT uses computational fluid dynamics (CFD) to evaluate FFR non-invasively by simulating coronary flow in geometries reconstructed from…

The circulatory system, comprising the heart and blood vessels, is vital for nutrient transport, waste removal, and homeostasis. Traditional computational models often treat cardiac electromechanics and blood flow dynamics separately,…

Ultrafast power Doppler imaging (uPDI) has become a powerful tool for both research and clinical applications. However, existing simulation tools are insufficient for generating quantitatively accurate three-dimensional (3D) flow fields…

信号处理 · 电气工程与系统科学 2025-10-28 Qiang Fu , Changhui Li

This paper introduces a novel dynamical pressure boundary condition for weakly-compressible smoothed particle hydrodynamics (WCSPH). Unlike previous methods that rely on indirect approaches or ghost particles, our method integrates the…

流体动力学 · 物理学 2025-03-05 Shuoguo Zhang , Yu Fan , Dong Wu , Chi Zhang , Xiangyu Hu

Purpose- Coarctation of the Aorta (CoA) patient-specific computational fluid dynamics (CFD) studies in resource constrained settings are limited by the available imaging modalities for geometry and velocity data acquisition. Doppler…

计算工程、金融与科学 · 计算机科学 2025-06-04 Vincent Milimo Masilokwa Punabantu , Malebogo Ngoepe , Amit Kumar Mishra , Thomas Aldersley , John Lawrenson , Liesl Zuhlke

Hemodynamic parameters such as pressure and wall shear stress play an important role in diagnosis, prognosis, and treatment planning in cardiovascular diseases. These parameters can be accurately computed using computational fluid dynamics…

计算机视觉与模式识别 · 计算机科学 2025-08-28 Patryk Rygiel , Julian Suk , Kak Khee Yeung , Christoph Brune , Jelmer M. Wolterink

Accurate 3D aortic construction is crucial for clinical diagnosis, preoperative planning, and computational fluid dynamics (CFD) simulations, as it enables the estimation of critical hemodynamic parameters such as blood flow velocity,…

计算机视觉与模式识别 · 计算机科学 2025-07-21 Delin An , Pan Du , Jian-Xun Wang , Chaoli Wang

In this study OpenFOAM 4.4.2 was used to investigate flow inside the coronary artery of the heart. This step is the first step of our future project, which is to include conjugate heat transfer of the heart with three main coronary…

医学物理 · 物理学 2021-07-19 Mohammadreza Nezamirad , Nasim Sabetpour , Azadeh Yazdi , Amirmasoud Hamedi

Predictive modeling of blood flow and pressure have numerous applications ranging from non-invasive assessment of functional significance of disease to planning invasive procedures. While several such predictive modeling techniques have…

Abdominal aortic aneurysms (AAAs) are pathologic dilatations of the abdominal aorta posing a high fatality risk upon rupture. Studying AAA progression and rupture risk often involves in-silico blood flow modelling with computational fluid…

计算机视觉与模式识别 · 计算机科学 2025-07-31 Patryk Rygiel , Julian Suk , Christoph Brune , Kak Khee Yeung , Jelmer M. Wolterink

Despite tremendous advances in cardiovascular medicine, significant opportunities remain to improve coronary artery disease (CAD) prevention and treatment strategies. The key limitation lies in the understanding of disease formation and…

Aortic stenosis (AS) is the most common valvular heart disease in developed countries. High-fidelity preclinical models can improve AS management by enabling therapeutic innovation, early diagnosis, and tailored treatment planning. However,…

Measuring the blood pressure waveform is becoming a more frequently studied area. The development of sensor technologies opens many new ways to be able to measure high-quality signals. The development of such an aim-specific sensor can be…

医学物理 · 物理学 2025-06-06 Attila Répai , Sándor Földi , Péter Sótonyi , György Cserey

Intracranial aneurysms remain a major cause of neurological morbidity and mortality worldwide, where rupture risk is tightly coupled to local hemodynamics particularly wall shear stress and oscillatory shear index. Conventional…

The analysis of quantitative hemodynamics and luminal pressure may add valuable information to aid treatment strategies and prognosis for aortic dissections. This work directly compared in vitro 4D-flow magnetic resonance imaging (MRI),…

It is known that the maximum diameter for the rupture-risk assessment of the abdominal aortic aneurysm is a generally good method, but not sufficient. Alternative features obtained with computational modeling may provide additional useful…

计算工程、金融与科学 · 计算机科学 2020-03-16 Shanlin Qin , Rongliang Chen , Bokai Wu , Jia Liu , Wen-Shin Shiu , Zhengzheng Yan , Xiao-Chuan Cai

Background and Objective: The role of red blood cell dynamics is emphasised in certain cardiovascular diseases, and thus needs to be closely studied. A multiphase model of blood flow allows the resolution of locally varying density of red…

流体动力学 · 物理学 2021-10-07 Konstantinos G. Lyras , Jack Lee