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Protein structure prediction often hinges on multiple sequence alignments (MSAs), which underperform on low-homology and orphan proteins. We introduce PLAME, a lightweight MSA design framework that leverages evolutionary embeddings from…

Due to the advantage of achieving a better performance under weak regularization, elastic net has attracted wide attention in statistics, machine learning, bioinformatics, and other fields. In particular, a variation of the elastic net,…

机器学习 · 统计学 2018-06-14 Xin-Guang Yang , Yongjin Lu

In this study, we present an interpretable deep learning framework for the early detection of breast cancer using quantitative features extracted from digitized fine needle aspirate (FNA) images of breast masses. Our deep neural network,…

计算机视觉与模式识别 · 计算机科学 2025-10-28 Bishal Chhetri , B. V. Rathish Kumar

Approximate Bayesian computation (ABC) or likelihood-free inference algorithms are used to find approximations to posterior distributions without making explicit use of the likelihood function, depending instead on simulation of sample data…

统计计算 · 统计学 2015-09-08 Richard D. Wilkinson

Deep learning has redefined the field of artificial intelligence (AI) thanks to the rise of artificial neural networks, which are architectures inspired by their neurological counterpart in the brain. Through the years, this dualism between…

机器学习 · 计算机科学 2023-02-21 Tommaso Salvatori , Yuhang Song , Thomas Lukasiewicz , Rafal Bogacz , Zhenghua Xu

The success of convolutional neural networks (CNNs) in various applications is accompanied by a significant increase in computation and parameter storage costs. Recent efforts to reduce these overheads involve pruning and compressing the…

In this paper, Artificial Bee Colony (ABC) algorithm which inspired from the behavior of honey bees swarm is presented. ABC is a stochastic population-based evolutionary algorithm for problem solving. ABC algorithm, which is considered one…

计算工程、金融与科学 · 计算机科学 2014-02-28 Osman Hegazy , Omar S. Soliman , Mustafa Abdul Salam

A key step in interpreting gas-phase ion mobility coupled with mass spectrometry (IM-MS) data for unknown structure prediction involves identifying the most favorable protonated structure. In the gas phase, the site of protonation is…

机器学习 · 计算机科学 2024-11-28 Hongni Jin , Kenneth M. Merz

The shortage of nephrologists and the growing public health concern over renal failure have spurred the demand for AI systems capable of autonomously detecting kidney abnormalities. Renal failure, marked by a gradual decline in kidney…

计算机视觉与模式识别 · 计算机科学 2024-04-26 Tahmim Hossain , Faisal Sayed , Solehin Islam

A biologically plausible method for training an Artificial Neural Network (ANN) involves treating each unit as a stochastic Reinforcement Learning (RL) agent, thereby considering the network as a team of agents. Consequently, all units can…

机器学习 · 计算机科学 2023-07-26 Stephen Chung

Approximate Bayesian Computation (ABC) methods are increasingly used for inference in situations in which the likelihood function is either computationally costly or intractable to evaluate. Extensions of the basic ABC rejection algorithm…

统计计算 · 统计学 2020-05-01 Umberto Simola , Jessica Cisewski-Kehe , Michael U. Gutmann , Jukka Corander

While convolutional neural networks (CNN) have achieved impressive performance on various classification/recognition tasks, they typically consist of a massive number of parameters. This results in significant memory requirement as well as…

计算机视觉与模式识别 · 计算机科学 2019-05-14 Pravendra Singh , Vinay Kumar Verma , Piyush Rai , Vinay P. Namboodiri

Breast cancer is not preventable because of its unknown causes. However, its early diagnosis increases patients' recovery chances. Machine learning (ML) can be utilized to improve treatment outcomes in healthcare operations while…

机器学习 · 计算机科学 2024-08-09 Kamyab Karimi , Ali Ghodratnama , Reza Tavakkoli-Moghaddam

The field of artificial intelligence faces significant challenges in achieving both biological plausibility and computational efficiency, particularly in visual learning tasks. Current artificial neural networks, such as convolutional…

机器学习 · 计算机科学 2024-09-27 Jacobo Ruiz , Manas Gupta

Approximate Bayesian computation (ABC) is a family of computational techniques in Bayesian statistics. These techniques allow to fi t a model to data without relying on the computation of the model likelihood. They instead require to…

统计理论 · 数学 2018-12-27 Maxime Lenormand , Franck Jabot , Guillaume Deffuant

Successful motor-imagery brain-computer interface (MI-BCI) algorithms either extract a large number of handcrafted features and train a classifier, or combine feature extraction and classification within deep convolutional neural networks…

信号处理 · 电气工程与系统科学 2020-10-15 Michael Hersche , Luca Benini , Abbas Rahimi

Performing exact posterior inference in complex generative models is often difficult or impossible due to an expensive to evaluate or intractable likelihood function. Approximate Bayesian computation (ABC) is an inference framework that…

机器学习 · 统计学 2016-02-16 Jovana Mitrovic , Dino Sejdinovic , Yee Whye Teh

Although convolutional neural networks (CNNs) are now widely used in various computer vision applications, its huge resource demanding on parameter storage and computation makes the deployment on mobile and embedded devices difficult.…

计算机视觉与模式识别 · 计算机科学 2019-09-26 Zhe Xu , Ray C. C. Cheung

We present APQ for efficient deep learning inference on resource-constrained hardware. Unlike previous methods that separately search the neural architecture, pruning policy, and quantization policy, we optimize them in a joint manner. To…

机器学习 · 计算机科学 2020-06-16 Tianzhe Wang , Kuan Wang , Han Cai , Ji Lin , Zhijian Liu , Song Han

Structured pruning techniques have achieved great compression performance on convolutional neural networks for image classification task. However, the majority of existing methods are weight-oriented, and their pruning results may be…

计算机视觉与模式识别 · 计算机科学 2022-08-16 Yiheng Lu , Ziyu Guan , Yaming Yang , Maoguo Gong , Wei Zhao , Kaiyuan Feng