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Diffusion and flow matching models have unlocked unprecedented capabilities for creative content creation, such as interactive image and streaming video generation. The growing demand for higher resolutions, frame rates, and context…

计算机视觉与模式识别 · 计算机科学 2026-03-25 Brian Chao , Lior Yariv , Howard Xiao , Gordon Wetzstein

Inspired by recent findings that generative diffusion models learn semantically meaningful representations, we use them to discover the intrinsic hierarchical structure in biomedical 3D images using unsupervised segmentation. We show that…

计算机视觉与模式识别 · 计算机科学 2023-10-11 Nurislam Tursynbek , Marc Niethammer

Recent works on text-to-3d generation show that using only 2D diffusion supervision for 3D generation tends to produce results with inconsistent appearances (e.g., faces on the back view) and inaccurate shapes (e.g., animals with extra…

计算机视觉与模式识别 · 计算机科学 2024-03-15 Cheng Chen , Xiaofeng Yang , Fan Yang , Chengzeng Feng , Zhoujie Fu , Chuan-Sheng Foo , Guosheng Lin , Fayao Liu

Many inverse problems are ill-posed and need to be complemented by prior information that restricts the class of admissible models. Bayesian approaches encode this information as prior distributions that impose generic properties on the…

机器学习 · 计算机科学 2024-12-20 Julian L. Möbius , Michael Habeck

Recent 3D large reconstruction models typically employ a two-stage process, including first generate multi-view images by a multi-view diffusion model, and then utilize a feed-forward model to reconstruct images to 3D content.However,…

计算机视觉与模式识别 · 计算机科学 2024-07-30 Zhenyu Tang , Junwu Zhang , Xinhua Cheng , Wangbo Yu , Chaoran Feng , Yatian Pang , Bin Lin , Li Yuan

We introduce a new generative model that combines latent diffusion with persistent homology to create 3D shapes with high diversity, with a special emphasis on their topological characteristics. Our method involves representing 3D shapes as…

计算机视觉与模式识别 · 计算机科学 2024-02-01 Jiangbei Hu , Ben Fei , Baixin Xu , Fei Hou , Weidong Yang , Shengfa Wang , Na Lei , Chen Qian , Ying He

In medical imaging, the diffusion models have shown great potential for synthetic image generation tasks. However, these approaches often lack the interpretable connections between the generated and real images and can create anatomically…

图像与视频处理 · 电气工程与系统科学 2026-02-12 Jian-Qing Zheng , Yuanhan Mo , Yang Sun , Jiahua Li , Fuping Wu , Ziyang Wang , Tonia Vincent , Bartłomiej W. Papież

While diffusion models have shown great potential in portrait generation, generating expressive, coherent, and controllable cinematic portrait videos remains a significant challenge. Existing intermediate signals for portrait generation,…

计算机视觉与模式识别 · 计算机科学 2026-03-26 Junyi Wang , Yudong Guo , Boyang Guo , Shengming Yang , Juyong Zhang

Generative models have shown great promise in generating 3D geometric systems, which is a fundamental problem in many natural science domains such as molecule and protein design. However, existing approaches only operate on static…

计算机视觉与模式识别 · 计算机科学 2024-10-18 Jiaqi Han , Minkai Xu , Aaron Lou , Haotian Ye , Stefano Ermon

Deep learning has achieved tremendous success in designing novel chemical compounds with desirable pharmaceutical properties. In this work, we focus on a new type of drug design problem -- generating a small "linker" to physically attach…

机器学习 · 计算机科学 2022-05-17 Yinan Huang , Xingang Peng , Jianzhu Ma , Muhan Zhang

Recent years have seen remarkable progress in both multimodal understanding models and image generation models. Despite their respective successes, these two domains have evolved independently, leading to distinct architectural paradigms:…

计算机视觉与模式识别 · 计算机科学 2026-01-27 Shanshan Zhao , Xinjie Zhang , Jintao Guo , Jiakui Hu , Lunhao Duan , Minghao Fu , Yong Xien Chng , Guo-Hua Wang , Qing-Guo Chen , Zhao Xu , Weihua Luo , Kaifu Zhang

The generation of stylistic 3D facial animations driven by speech presents a significant challenge as it requires learning a many-to-many mapping between speech, style, and the corresponding natural facial motion. However, existing methods…

计算机视觉与模式识别 · 计算机科学 2024-05-15 Zhiyao Sun , Tian Lv , Sheng Ye , Matthieu Lin , Jenny Sheng , Yu-Hui Wen , Minjing Yu , Yong-Jin Liu

3D head stylization has emerged as a key technique for reimagining realistic human heads in various artistic forms, enabling expressive character design and creative visual experiences in digital media. Despite the progress in 3D-aware…

计算机视觉与模式识别 · 计算机科学 2025-12-01 Furkan Guzelant , Arda Goktogan , Tarık Kaya , Aysegul Dundar

Current 4D generation methods have achieved noteworthy efficacy with the aid of advanced diffusion generative models. However, these methods lack multi-view spatial-temporal modeling and encounter challenges in integrating diverse prior…

计算机视觉与模式识别 · 计算机科学 2024-10-23 Haiyu Zhang , Xinyuan Chen , Yaohui Wang , Xihui Liu , Yunhong Wang , Yu Qiao

Drug development is a critical but notoriously resource- and time-consuming process. In this manuscript, we develop a novel generative artificial intelligence (genAI) method DiffSMol to facilitate drug development. DiffSmol generates 3D…

机器学习 · 计算机科学 2025-02-11 Ziqi Chen , Bo Peng , Tianhua Zhai , Daniel Adu-Ampratwum , Xia Ning

Effective generation of molecular structures, or new chemical entities, that bind to target proteins is crucial for lead identification and optimization in drug discovery. Despite advancements in atom- and motif-wise deep learning models…

机器学习 · 计算机科学 2025-03-04 Guanlue Li , Chenran Jiang , Ziqi Gao , Yu Liu , Chenyang Liu , Jiean Chen , Yong Huang , Jia Li

The goal of structure-based drug discovery is to find small molecules that bind to a given target protein. Deep learning has been used to generate drug-like molecules with certain cheminformatic properties, but has not yet been applied to…

定量方法 · 定量生物学 2022-01-27 Matthew Ragoza , Tomohide Masuda , David Ryan Koes

Diffusion models have shown great promise for image generation, beating GANs in terms of generation diversity, with comparable image quality. However, their application to 3D shapes has been limited to point or voxel representations that…

计算机视觉与模式识别 · 计算机科学 2022-12-16 Gimin Nam , Mariem Khlifi , Andrew Rodriguez , Alberto Tono , Linqi Zhou , Paul Guerrero

Text-guided diffusion models have shown superior performance in image/video generation and editing. While few explorations have been performed in 3D scenarios. In this paper, we discuss three fundamental and interesting problems on this…

计算机视觉与模式识别 · 计算机科学 2023-10-13 Gang Li , Heliang Zheng , Chaoyue Wang , Chang Li , Changwen Zheng , Dacheng Tao

While many unsupervised learning models focus on one family of tasks, either generative or discriminative, we explore the possibility of a unified representation learner: a model which addresses both families of tasks simultaneously. We…