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We introduce algorithms for robustly computing intrinsic coordinates on point clouds. Our approach relies on generating many candidate coordinates by subsampling the data and varying hyperparameters of the embedding algorithm (e.g.,…

机器学习 · 统计学 2024-08-05 Andrew J. Blumberg , Mathieu Carriere , Jun Hou Fung , Michael A. Mandell

Given the inner complexity of the human nervous system, insight into the dynamics of brain activity can be gained from understanding smaller and simpler organisms, such as the nematode C. Elegans. The behavioural and structural biology of…

神经元与认知 · 定量生物学 2021-07-15 Gonçalo Mestre , Ruxandra Barbulescu , Arlindo L. Oliveira , L. Miguel Silveira

Neural manifolds summarize the intrinsic structure of the information encoded by a population of neurons. Advances in experimental techniques have made simultaneous recordings from multiple brain regions increasingly commonplace, raising…

神经元与认知 · 定量生物学 2025-03-27 Iris H. R. Yoon , Gregory Henselman-Petrusek , Yiyi Yu , Robert Ghrist , Spencer LaVere Smith , Chad Giusti

The 1mm roundworm C. elegans is a model organism used in many sub-areas of biology to investigate different types of biological processes. In order to complement the n-vivo analysis with computer-based investigations, several methods have…

定量方法 · 定量生物学 2025-10-02 Nemanja Antonic , Monika Scholz , Aymeric Vellinger , Euphrasie Ramahefarivo , Elio Tuci

There is a growing interest in characterizing circular data found in biological systems. Such data are wide ranging and varied, from signal phase in neural recordings to nucleotide sequences in round genomes. Traditional clustering…

机器学习 · 计算机科学 2023-09-19 Xiaoxiao Sun , Paul Sajda

Matrices are two-dimensional data structures allowing one to conceptually organize information. For example, adjacency matrices are useful to store the links of a network; correlation matrices are simple ways to arrange gene co-expression…

无序系统与神经网络 · 物理学 2022-09-29 Flaviano Morone

Dimensionality reduction is a crucial technique in data analysis, as it allows for the efficient visualization and understanding of high-dimensional datasets. The circular coordinate is one of the topological data analysis techniques…

代数拓扑 · 数学 2023-01-31 Taejin Paik , Jaemin Park

Network structure or topology is the basis for understanding complex systems. Recently, higher-order structures have been considered as a new research direction that can provide new perspectives and phenomena. However, most existing studies…

神经元与认知 · 定量生物学 2022-12-08 Bo Liu , Rongmei Yang , Hao Wang , Linyuan Lü

We investigate how locomotory behavior is generated in the brain focusing on the paradigmatic connectome of nematode Caenorhabditis elegans (C. elegans) and on neuronal activity patterns that control forward locomotion. We map the neuronal…

适应与自组织系统 · 物理学 2020-06-17 Thomas Maertens , Eckehard Schöll , Jorge Ruiz , Philipp Hövel

Recordings of whole brain activity with single neuron resolution are now feasible in simple organisms. Yet, it is still challenging to appropriately simplify such complex, noisy, and multivariate data in order to reveal general principles…

神经元与认知 · 定量生物学 2017-11-27 Connor Brennan , Alex Proekt

We propose to use stochastic Riemannian coordinate descent on the orthogonal group for recurrent neural network training. The algorithm rotates successively two columns of the recurrent matrix, an operation that can be efficiently…

机器学习 · 计算机科学 2021-08-03 Estelle Massart , Vinayak Abrol

Understanding the dynamical behavior of complex systems from their underlying network architectures is a long-standing question in complexity theory. Therefore, many metrics have been devised to extract network features like motifs,…

神经元与认知 · 定量生物学 2024-09-05 Bryant Avila , Pedro Augusto , David Phillips , Tommaso Gili , Manuel Zimmer , Hernán A. Makse

Manifold reconstruction has been extensively studied for the last decade or so, especially in two and three dimensions. Recently, significant improvements were made in higher dimensions, leading to new methods to reconstruct large classes…

计算几何 · 计算机科学 2007-12-18 Frédéric Chazal , Steve Oudot

Proper regularization is critical for speeding up training, improving generalization performance, and learning compact models that are cost efficient. We propose and analyze regularized gradient descent algorithms for learning shallow…

机器学习 · 计算机科学 2018-06-08 Samet Oymak

We consider the problem of minimizing a sum of $n$ functions over a convex parameter set $\mathcal{C} \subset \mathbb{R}^p$ where $n\gg p\gg 1$. In this regime, algorithms which utilize sub-sampling techniques are known to be effective. In…

机器学习 · 统计学 2015-12-03 Murat A. Erdogdu , Andrea Montanari

Datasets with sheer volume have been generated from fields including computer vision, medical imageology, and astronomy whose large-scale and high-dimensional properties hamper the implementation of classical statistical models. To tackle…

统计理论 · 数学 2023-05-30 Hang Yu , Zhenxing Dou , Zhiwei Chen , Xiaomeng Yan

Animal behavior is often quantified through subjective, incomplete variables that may mask essential dynamics. Here, we develop a behavioral state space in which the full instantaneous state is smoothly unfolded as a combination of…

神经元与认知 · 定量生物学 2019-12-02 Tosif Ahamed , Antonio Carlos Costa , Greg J. Stephens

Getting a robust time-series clustering with best choice of distance measure and appropriate representation is always a challenge. We propose a novel mechanism to identify the clusters combining learned compact representation of…

机器学习 · 计算机科学 2021-01-12 Soma Bandyopadhyay , Anish Datta , Arpan Pal

We develop an artificial neural circuit for contour tracking and navigation inspired by the chemotaxis of the nematode Caenorhabditis elegans. In order to harness the computational advantages spiking neural networks promise over their…

神经与进化计算 · 计算机科学 2014-10-30 Shibani Santurkar , Bipin Rajendran

In this paper, we introduce Channel-wise recurrent convolutional neural networks (RecNets), a family of novel, compact neural network architectures for computer vision tasks inspired by recurrent neural networks (RNNs). RecNets build upon…

机器学习 · 计算机科学 2020-03-23 George Retsinas , Athena Elafrou , Georgios Goumas , Petros Maragos
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