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Deep neural networks have shown potential in analyzing digitized hand-drawn signals for early diagnosis of Parkinson's disease. However, the lack of clear interpretability in existing diagnostic methods presents a challenge to clinical…

计算机视觉与模式识别 · 计算机科学 2025-05-08 Xuechao Wang , Sven Nomm , Junqing Huang , Kadri Medijainen , Aaro Toomela , Michael Ruzhansky

Passive and non-obtrusive health monitoring using wearables can potentially bring new insights into the user's health status throughout the day and may support clinical diagnosis and treatment. However, identifying segments of free-living…

信号处理 · 电气工程与系统科学 2019-01-31 Yordan P. Raykov , Luc J. W. Evers , Reham Badawy , Marjan J. Faber , Bastiaan R. Bloem , Kasper Claes , Max A. Little

Despite the widespread adoption of Virtual Reality (VR) technology, cybersickness remains a barrier for some users. This research investigates head movement patterns as a novel physiological marker for cybersickness detection. Unlike…

机器学习 · 计算机科学 2024-02-28 Masoud Salehi , Nikoo Javadpour , Brietta Beisner , Mohammadamin Sanaei , Stephen B. Gilbert

Identification of risk factors associated with falls in people with Parkinson's Disease (PD) is important due to their high risk of falling. In this study, various ways of utilizing the Unified Parkinson's Disease Rating Scale (UPDRS) were…

应用统计 · 统计学 2019-10-04 Sarini Abdullah , Nicole White , James McGree , Kerrie Mengersen , Graham Kerr

Parkinsons disease (PD) diagnosis is challenging due to subtle early clinical signs. F-DOPA PET is commonly used for early PD diagnosis. We explore the potential of machine-learning (ML) based EEG features extracted from single-channel EEG…

神经元与认知 · 定量生物学 2023-08-08 Lior Molcho , Neta B. Maimon , Neomi Hezi , Talya Zeimer , Nathan Intrator , Tanya Gurevich

In heterogeneous disorders like Parkinson's disease (PD), differentiating the affected population into subgroups plays a key role in future research. Discovering subgroups can lead to improved treatments through more powerful enrichment of…

统计方法学 · 统计学 2023-08-08 Elliot Burghardt , Daniel Sewell , Joseph Cavanaugh

We search for digital biomarkers from Parkinson's Disease by observing approximate repetitive patterns matching hypothesized step and stride periodic cycles. These observations were modeled as a cycle of hidden states with randomness…

定量方法 · 定量生物学 2017-11-15 Avinash Bukkittu , Baihan Lin , Trung Vu , Itsik Pe'er

Parkinson's disease is a common neurological disease, entailing a multitude of motor deficiency symptoms. In this project, we developed a device with an uploaded edge machine learning algorithm that can detect the onset of freezing of gait…

信号处理 · 电气工程与系统科学 2022-11-15 Purnoor Ghuman , Tyama Lyall , Usama Mahboob , Alia Aamir , Xilin Liu

Early and accurate identification of parkinsonian syndromes (PS) involving presynaptic degeneration from non-degenerative variants such as Scans Without Evidence of Dopaminergic Deficit (SWEDD) and tremor disorders, is important for…

应用统计 · 统计学 2017-03-07 R. Prashanth , Sumantra Dutta Roy , Pravat K. Mandal , Shantanu Ghosh

PPINtonus is a system for the early detection of Parkinson's Disease (PD) utilizing deep-learning tonal analysis, providing a cost-effective and accessible alternative to traditional neurological examinations. Partnering with the…

音频与语音处理 · 电气工程与系统科学 2024-06-06 Varun Reddy

Early and accurate detection of Parkinson's disease (PD) remains a critical challenge in medical diagnostics due to the subtlety of early-stage symptoms and the complex, non-linear relationships inherent in biomedical data. Traditional…

机器学习 · 计算机科学 2026-02-10 Olamide Samuel Oseni , Ibraheem Omotolani Obanla , Toheeb Aduramomi Jimoh

One of the symptoms of Parkinson's disease (PD) is hypomimia or reduced facial expressions. In this paper, we present a digital biomarker for PD that utilizes the study of micro-expressions. We analyzed the facial action units (AU) from…

人机交互 · 计算机科学 2021-09-06 Mohammad Rafayet Ali , Taylor Myers , Ellen Wagner , Harshil Ratnu , E. Ray Dorsey , Ehsan Hoque

Parkinson's disease (PD) is a common neurodegenerative disorder that severely diminishes patients' quality of life. Its global prevalence has increased markedly in recent decades. Current diagnostic workflows are complex and heavily reliant…

计算机视觉与模式识别 · 计算机科学 2026-03-12 Shuai Shao , Yan Wang , Shu Jiang , Shiyuan Zhao , Di Yang , Jiangtao Wang , Yutong Bai , Jianguo Zhang

There is great interest in developing radiological classifiers for diagnosis, staging, and predictive modeling in progressive diseases such as Parkinson's disease (PD), a neurodegenerative disease that is difficult to detect in its early…

The study presents the concept of a computationally efficient machine learning (ML) model for diagnosing and monitoring Parkinson's disease (PD) in an Internet of Things (IoT) environment using rest-state EEG signals (rs-EEG). We computed…

信号处理 · 电气工程与系统科学 2023-09-15 Maksim Belyaev , Murugappan Murugappan , Andrei Velichko , Dmitry Korzun

Current diagnosis and prognosis for Parkinson's disease (PD) face formidable challenges due to the heterogeneous nature of the disease course, including that (i) the impairment severity varies hugely between patients, (ii) whether a symptom…

应用统计 · 统计学 2024-10-03 Kai Kang , Yuqi Gu

The automatic identification of medication states of Parkinson's disease (PD) patients can assist clinicians in monitoring and scheduling personalized treatments, as well as studying the effects of medication in alleviating the motor…

Eye-tracking is an accessible and non-invasive technology that provides information about a subject's motor and cognitive abilities. As such, it has proven to be a valuable resource in the study of neurodegenerative diseases such as…

机器学习 · 计算机科学 2023-11-29 Gonzalo Uribarri , Simon Ekman von Huth , Josefine Waldthaler , Per Svenningsson , Erik Fransén

In many clinical trials studying neurodegenerative diseases such as Parkinson's disease (PD), multiple longitudinal outcomes are collected to fully explore the multidimensional impairment caused by this disease. If the outcomes deteriorate…

应用统计 · 统计学 2017-05-18 Jue Wang , Sheng Luo , Liang Li

Parkinson's disease (PD) is a progressive disorder in which symptom burden and functional impairment evolve over time, making severity staging essential for clinical monitoring and treatment planning. However, many computational studies…

机器学习 · 计算机科学 2026-04-21 Md Mezbahul Islam , John Michael Templeton , Christian Poellabauer , Ananda Mohan Mondal