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At present, the vast majority of human subjects with neurological disease are still diagnosed through in-person assessments and qualitative analysis of patient data. In this paper, we propose to use Topological Data Analysis (TDA) together…

机器学习 · 计算机科学 2020-05-07 Afra Nawar , Farhan Rahman , Narayanan Krishnamurthi , Anirudh Som , Pavan Turaga

Parkinson's disease (PD) is the second most common neurodegenerative disease worldwide and affects around 1% of the (60+ years old) elderly population in industrial nations. More than 80% of PD patients suffer from motor symptoms, which…

Motor dysfunction is a common sign of neurodegenerative diseases (NDs) such as Parkinson's disease (PD) and Alzheimer's disease (AD), but may be difficult to detect, especially in the early stages. In this work, we examine the behavior of a…

神经元与认知 · 定量生物学 2025-10-23 Thomas Thebaud , Anna Favaro , Casey Chen , Gabrielle Chavez , Laureano Moro-Velazquez , Ankur Butala , Najim Dehak

Parkinson's Disease (PD) is one of the most common types of neurological diseases caused by progressive degeneration of dopamin- ergic neurons in the brain. Even though there is no fixed cure for this neurodegenerative disease, earlier…

计算机视觉与模式识别 · 计算机科学 2018-06-21 Sara Soltaninejad , Irene Cheng , Anup Basu

Parkinson's disease (PD) is a neurodegenerative condition characterized by frequently changing motor symptoms, necessitating continuous symptom monitoring for more targeted treatment. Classical time series classification and deep learning…

机器学习 · 计算机科学 2025-06-03 Cedric Donié , Neha Das , Satoshi Endo , Sandra Hirche

The rapid emergence of highly adaptable and reusable artificial intelligence (AI) models is set to revolutionize the medical field, particularly in the diagnosis and management of Parkinson's disease (PD). Currently, there are no effective…

机器学习 · 计算机科学 2025-02-18 Aite Zhao , Yongcan Liu , Xinglin Yu , Xinyue Xing

In recent years, applications of data mining methods are become more popular in many fields of medical diagnosis and evaluations. The data mining methods are appropriate tools for discovering and extracting of available knowledge in medical…

计算工程、金融与科学 · 计算机科学 2013-12-10 Peyman Mohammadi , Abdolreza Hatamlou , Mohammad Masdari

Parkinson's disease (PD) is a neurodegenerative condition characterized by notable motor and non-motor manifestations. The assessment tool known as the Unified Parkinson's Disease Rating Scale (UPDRS) plays a crucial role in evaluating the…

声音 · 计算机科学 2025-02-14 Arman Mohammadigilani , Hani Attar , Hamidreza Ehsani Chimeh , Mostafa Karami

This paper presents a new method for medical diagnosis of neurodegenerative diseases, such as Parkinson's, by extracting and using latent information from trained Deep convolutional, or convolutional-recurrent Neural Networks (DNNs). In…

机器学习 · 计算机科学 2019-01-24 Ilianna Kollia , Andreas-Georgios Stafylopatis , Stefanos Kollias

Parkinson's disease is a progressive neurodegenerative disorder affecting motor and non-motor functions, with speech impairments among its earliest symptoms. Speech impairments offer a valuable diagnostic opportunity, with machine learning…

Objective: The aim of this study is to develop a smartphone-based high-frequency remote monitoring platform, assess its feasibility for remote monitoring of symptoms in Parkinson's disease, and demonstrate the value of data collected using…

计算机与社会 · 计算机科学 2016-01-06 Andong Zhan , Max A. Little , Denzil A. Harris , Solomon O. Abiola , E. Ray Dorsey , Suchi Saria , Andreas Terzis

The paper presents a novel approach, based on deep learning, for diagnosis of Parkinson's disease through medical imaging. The approach includes analysis and use of the knowledge extracted by Deep Convolutional and Recurrent Neural Networks…

机器学习 · 计算机科学 2019-11-26 James Wingate , Ilianna Kollia , Luc Bidaut , Stefanos Kollias

Parkinson's disease (PD) is a common neurodegenerative disorder with a poorly understood physiopathology and no established biomarkers for the diagnosis of early stages and for prediction of disease progression. Several neuroimaging…

Discriminating between Parkinson's Disease (PD) and Progressive Supranuclear Palsy (PSP) is difficult due to overlapping symptoms, especially early on. Saccades (rapid conjugate eye movements between fixation points) are affected by both…

定量方法 · 定量生物学 2024-07-25 Salil B Patel , Oliver B Bredemeyer , James J FitzGerald , Chrystalina A Antoniades

People with Parkinson's disease must be regularly monitored by their physician to observe how the disease is progressing and potentially adjust treatment plans to mitigate the symptoms. Monitoring the progression of the disease through a…

音频与语音处理 · 电气工程与系统科学 2022-05-25 Mohammadreza Iman , Amy Giuntini , Hamid Reza Arabnia , Khaled Rasheed

In this work, we explore various neural network architectures using Magnetic Resonance (MR) T1 images of the brain to identify Parkinson's Disease (PD), which is one of the most common neurodegenerative and movement disorders. We propose…

图像与视频处理 · 电气工程与系统科学 2020-07-27 Tahjid Ashfaque Mostafa , Irene Cheng

Eye movements can reveal early signs of neurodegeneration, including those associated with Parkinson's Disease (PD). This work investigates the utility of a set of gaze-based features for the automatic screening of PD from different visual…

Sensors from smart consumer devices have demonstrated high potential to serve as digital biomarkers in the identification of movement disorders in recent years. With the usage of broadly available smartwatches we have recorded participants…

机器学习 · 计算机科学 2022-05-12 Alexander Brenner , Michael Fujarski , Tobias Warnecke , Julian Varghese

Parkinsons disease, the fastest growing neurodegenerative disorder globally, has seen a 50 percent increase in cases within just two years. As speech, memory, and motor symptoms worsen over time, early diagnosis is crucial for preserving…

定量方法 · 定量生物学 2024-12-02 Diya Vatsavai , Anya Iyer , Ashwin A. Nair

Parkinson's disease (PD) is a slowly progressive debilitating neurodegenerative disease which is prominently characterised by motor symptoms. Indoor localisation, including number and speed of room to room transitions, provides a proxy…

机器学习 · 计算机科学 2022-05-13 Ferdian Jovan , Ryan McConville , Catherine Morgan , Emma Tonkin , Alan Whone , Ian Craddock