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FDA has been promoting enrollment practices that could enhance the diversity of clinical trial populations, through broadening eligibility criteria. However, how to broaden eligibility remains a significant challenge. We propose an AI…

计算与语言 · 计算机科学 2021-09-08 Xiong Liu , Cheng Shi , Uday Deore , Yingbo Wang , Myah Tran , Iya Khalil , Murthy Devarakonda

Recent advances in LLMs have greatly improved general-domain NLP tasks. Yet, their adoption in critical domains, such as clinical trial recruitment, remains limited. As trials are designed in natural language and patient data is represented…

计算与语言 · 计算机科学 2026-01-01 Shrestha Ghosh , Moritz Schneider , Carina Reinicke , Carsten Eickhoff

Skin cancer is one of the most common cancers worldwide and early detection is critical for effective treatment. However, current AI diagnostic tools are often trained on datasets dominated by lighter skin tones, leading to reduced accuracy…

计算机视觉与模式识别 · 计算机科学 2026-02-17 Areez Muhammed Shabu , Mohammad Samar Ansari , Asra Aslam

Clinical trials are critical for drug development. Constructing the appropriate eligibility criteria (i.e., the inclusion/exclusion criteria for patient recruitment) is essential for the trial's success. Proper design of clinical trial…

计算与语言 · 计算机科学 2023-10-10 Zifeng Wang , Cao Xiao , Jimeng Sun

Artificial intelligence (AI) is increasingly used in recruitment, yet empirical evidence quantifying its impact on hiring efficiency and candidate selection remains limited. We randomly assign 37,000 applicants for a junior-developer…

计算与语言 · 计算机科学 2025-07-14 Ada Aka , Emil Palikot , Ali Ansari , Nima Yazdani

A clinical trial is an essential step in drug development, which is often costly and time-consuming. In silico trials are clinical trials conducted digitally through simulation and modeling as an alternative to traditional clinical trials.…

定量方法 · 定量生物学 2022-09-20 Zifeng Wang , Chufan Gao , Lucas M. Glass , Jimeng Sun

Many diseases, including cancer and chronic conditions, require extended treatment periods and long-term strategies. Machine learning and AI research focusing on electronic health records (EHRs) have emerged to address this need. Effective…

Pathologists are facing an increasing workload due to a growing volume of cases and the need for more comprehensive diagnoses. Aiming to facilitate workload reduction and faster turnaround times, we developed an artificial intelligence (AI)…

计算机视觉与模式识别 · 计算机科学 2024-10-15 Ruben T. Lucassen , Nikolas Stathonikos , Gerben E. Breimer , Mitko Veta , Willeke A. M. Blokx

The rapid growth of Artificial Intelligence (AI) in healthcare has sparked interest in Trustworthy AI and AI Implementation Science, both of which are essential for accelerating clinical adoption. However, strict regulations, gaps between…

定量方法 · 定量生物学 2026-03-06 Benoit L. Marteau , Andrew Hornback , Shaun Q. Tan , Christian Lowson , Jason Woloff , May D. Wang

In pathological research, education, and clinical practice, the decision-making process based on pathological images is critically important. This significance extends to digital pathology image analysis: its adequacy is demonstrated by the…

图像与视频处理 · 电气工程与系统科学 2024-08-19 Zhi-Bo Liu , Xiaobo Pang , Jizhao Wang , Shuai Liu , Chen Li

While interest in the application of machine learning to improve healthcare has grown tremendously in recent years, a number of barriers prevent deployment in medical practice. A notable concern is the potential to exacerbate entrenched…

机器学习 · 计算机科学 2022-05-19 Isabel Chien , Nina Deliu , Richard E. Turner , Adrian Weller , Sofia S. Villar , Niki Kilbertus

In the pharmaceutical industry, the use of artificial intelligence (AI) has seen consistent growth over the past decade. This rise is attributed to major advancements in statistical machine learning methodologies, computational capabilities…

统计方法学 · 统计学 2023-12-01 Yuhan Li , Hongtao Zhang , Keaven Anderson , Songzi Li , Ruoqing Zhu

Background: An early diagnosis together with an accurate disease progression monitoring of multiple sclerosis is an important component of successful disease management. Prior studies have established that multiple sclerosis is correlated…

音频与语音处理 · 电气工程与系统科学 2021-09-28 Emil Svoboda , Tomáš Bořil , Jan Rusz , Tereza Tykalová , Dana Horáková , Charles R. G. Guttman , Krastan B. Blagoev , Hiroto Hatabu , Vlad I. Valtchinov

AI-generated health misinformation poses unprecedented threats to patient safety and healthcare system trust globally. This white paper presents an explainable AI framework developed through the EPSRC INDICATE project to combat medical…

信息检索 · 计算机科学 2025-09-05 Sueun Hong , Shuojie Fu , Ovidiu Serban , Brianna Bao , James Kinross , Francesa Toni , Guy Martin , Uddhav Vaghela

This paper examines records retrieved from the ClinicalTrials.gov registry to characterize temporal trends in AI terminology and the geographical distribution of AI trials. The work also reports on an exploratory hybrid human-AI approach to…

人工智能 · 计算机科学 2026-05-29 Sandra Woolley , Tim Collins , Khalid Khattak , Illia Chernomorets , Ariane Arevalo , Chris Richardson

Despite the promises of data-driven artificial intelligence (AI), little is known about how we can bridge the gulf between traditional physician-driven diagnosis and a plausible future of medicine automated by AI. Specifically, how can we…

人机交互 · 计算机科学 2021-02-12 Hongyan Gu , Jingbin Huang , Lauren Hung , Xiang 'Anthony' Chen

Purpose: Proton therapy provides superior dose conformity compared to photon therapy, but its treatment planning is challenged by sensitivity to anatomical changes, setup/range uncertainties, and computational complexity. This review…

We present a simple text mining method that is easy to implement, requires minimal data collection and preparation, and is easy to use for proposing ranked associations between a list of target terms and a key phrase. We call this method…

信息检索 · 计算机科学 2019-06-13 Finn Kuusisto , John Steill , Zhaobin Kuang , James Thomson , David Page , Ron Stewart

Background: In medical and health professions education (HPE), AI is increasingly used to assess clinical competencies, including via virtual standardized patients. However, most evaluations rely on AI-human interrater reliability and lack…

Artificial intelligence (AI) has the potential to revolutionize the drug discovery process, offering improved efficiency, accuracy, and speed. However, the successful application of AI is dependent on the availability of high-quality data,…