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Large language models (LLMs) have achieved remarkable breakthroughs in new dialogue capabilities by leveraging instruction tuning, which refreshes human impressions of dialogue systems. The long-standing goal of dialogue systems is to be…

计算与语言 · 计算机科学 2024-04-01 Jiao Ou , Junda Lu , Che Liu , Yihong Tang , Fuzheng Zhang , Di Zhang , Kun Gai

In contrast to their remarkable performance on general knowledge QA, the true abilities of Large Language Models (LLMs) in tasks demanding deep, specialized reasoning, such as in protein biology, have yet to be thoroughly investigated.…

定量方法 · 定量生物学 2025-12-30 Dingyi Rong , Zijian Chen , Qi Jia , Kaiwei Zhang , Haotian Lu , Guangtao Zhai , Ning Liu

This paper explores the use of Large Language Models (LLMs) to automate the generation of test skeletons -- structural templates that outline unit test coverage without implementing full test logic. Test skeletons are especially important…

软件工程 · 计算机科学 2025-09-08 Subhang Boorlagadda , Nitya Naga Sai Atluri , Muhammet Mustafa Olmez , Edward F. Gehringer

Proteins adopt multiple structural conformations to perform their diverse biological functions, and understanding these conformations is crucial for advancing drug discovery. Traditional physics-based simulation methods often struggle with…

生物大分子 · 定量生物学 2025-03-14 Jiarui Lu , Xiaoyin Chen , Stephen Zhewen Lu , Chence Shi , Hongyu Guo , Yoshua Bengio , Jian Tang

In light of the rapid adoption of AI coding assistants, LLM-assisted development has become increasingly prevalent, creating an urgent need for robust evaluation of generated code quality. Existing benchmarks often require extensive manual…

软件工程 · 计算机科学 2025-05-21 Yuancheng Jiang , Roland Yap , Zhenkai Liang

Deep learning has significantly advanced molecular modeling and design, enabling efficient understanding and discovery of novel molecules. In particular, large language models (LLMs) introduce a fresh research paradigm to tackle scientific…

机器学习 · 计算机科学 2025-01-06 Pengfei Liu , Jun Tao , Zhixiang Ren

Open Large Language Models (OLLMs) are increasingly leveraged in generative AI applications, posing new challenges for detecting their outputs. We propose OpenTuringBench, a new benchmark based on OLLMs, designed to train and evaluate…

计算与语言 · 计算机科学 2025-04-16 Lucio La Cava , Andrea Tagarelli

With the development of the Large Language Models (LLMs), a large range of LLM-based Text-to-SQL(Text2SQL) methods have emerged. This survey provides a comprehensive review of LLM-based Text2SQL studies. We first enumerate classic…

计算与语言 · 计算机科学 2025-06-04 Liang Shi , Zhengju Tang , Nan Zhang , Xiaotong Zhang , Zhi Yang

In last two years, large language models (LLMs) have shown strong capabilities in code generation, including hardware design at register-transfer level (RTL). While their use in high-level synthesis (HLS) remains comparatively less mature,…

硬件体系结构 · 计算机科学 2026-01-29 M Zafir Sadik Khan , Kimia Azar , Hadi Kamali

We introduce OSVBench, a new benchmark for evaluating Large Language Models (LLMs) on the task of generating complete formal specifications for verifying the functional correctness of operating system kernels. This benchmark is built upon a…

计算与语言 · 计算机科学 2025-12-09 Shangyu Li , Juyong Jiang , Tiancheng Zhao , Jiasi Shen

Automated molecular structure elucidation remains challenging, as existing approaches often depend on pre-compiled databases or restrict themselves to single spectroscopic modalities. Here we introduce SpectraLLM, a large language model…

定量方法 · 定量生物学 2026-05-12 Yunyue Su , Jiahui Chen , Zao Jiang , Zhenyi Zhong , Liang Wang , Qiang Liu , Zhaoxiang Zhang

Developing therapeutics is a lengthy and expensive process that requires the satisfaction of many different criteria, and AI models capable of expediting the process would be invaluable. However, the majority of current AI approaches…

The parallels between protein sequences and natural language in their sequential structures have inspired the application of large language models (LLMs) to protein understanding. Despite the success of LLMs in NLP, their effectiveness in…

定量方法 · 定量生物学 2024-07-09 Yiqing Shen , Zan Chen , Michail Mamalakis , Luhan He , Haiyang Xia , Tianbin Li , Yanzhou Su , Junjun He , Yu Guang Wang

Multimodal Large Language Models (MLLMs) are gaining increasing popularity in both academia and industry due to their remarkable performance in various applications such as visual question answering, visual perception, understanding, and…

计算与语言 · 计算机科学 2024-09-09 Jian Li , Weiheng Lu , Hao Fei , Meng Luo , Ming Dai , Min Xia , Yizhang Jin , Zhenye Gan , Ding Qi , Chaoyou Fu , Ying Tai , Wankou Yang , Yabiao Wang , Chengjie Wang

Recently, Large Language Models (LLMs) have demonstrated significant potential in automating software engineering tasks. Generating software architecture designs from requirement documents is a crucial step in software development. However,…

软件工程 · 计算机科学 2026-04-09 Minxiao Li , Shuying Yan , Li Zhang , Yang Liu , Fang Liu

Large Language Models (LLMs) have recently achieved impressive performance in math and reasoning benchmarks. However, they often struggle with logic problems and puzzles that are relatively easy for humans. To further investigate this, we…

人工智能 · 计算机科学 2025-09-16 Nasim Borazjanizadeh , Roei Herzig , Trevor Darrell , Rogerio Feris , Leonid Karlinsky

Language-molecule models have emerged as an exciting direction for molecular discovery and understanding. However, training these models is challenging due to the scarcity of molecule-language pair datasets. At this point, datasets have…

计算与语言 · 计算机科学 2024-07-08 Carl Edwards , Qingyun Wang , Lawrence Zhao , Heng Ji

LLMbench is a browser-based workbench for the comparative close reading of large language model (LLM) outputs. Where existing tools for LLM comparison, such as Google PAIR's LLM Comparator are engineered for quantitative evaluation and…

计算机与社会 · 计算机科学 2026-04-20 David M. Berry

Real-time speech-to-speech (S2S) models excel at generating natural, low-latency conversational responses but often lack deep knowledge and semantic understanding. Conversely, cascaded systems combining automatic speech recognition, a…

计算与语言 · 计算机科学 2026-05-26 So Kuroki , Yotaro Kubo , Takuya Akiba , Yujin Tang

Task automation has been greatly empowered by the recent advances in Large Language Models (LLMs) via Python code, where the tasks ranging from software engineering development to general-purpose reasoning. While current benchmarks have…