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Proteins adopt multiple structural conformations to perform their diverse biological functions, and understanding these conformations is crucial for advancing drug discovery. Traditional physics-based simulation methods often struggle with…

生物大分子 · 定量生物学 2025-03-14 Jiarui Lu , Xiaoyin Chen , Stephen Zhewen Lu , Chence Shi , Hongyu Guo , Yoshua Bengio , Jian Tang

This thesis focuses on improving the pre-training of natural language models using unsupervised raw data to make them more efficient and aligned with downstream applications. In the first part, we introduce three alternative pre-training…

计算与语言 · 计算机科学 2023-09-18 Luca Di Liello

Large Language Models (LLMs) have achieved remarkable success, yet recent findings reveal that their deeper layers often contribute minimally and can be pruned without affecting overall performance. While some view this as an opportunity…

机器学习 · 计算机科学 2025-08-05 Pengxiang Li , Lu Yin , Shiwei Liu

Modern neural language models (LMs) are powerful tools for modeling human sentence production and comprehension, and their internal representations are remarkably well-aligned with representations of language in the human brain. But to…

计算与语言 · 计算机科学 2024-03-27 Chengxu Zhuang , Evelina Fedorenko , Jacob Andreas

We introduce Medal S, a medical segmentation foundation model that supports native-resolution spatial and textual prompts within an end-to-end trainable framework. Unlike text-only methods lacking spatial awareness, Medal S achieves…

计算机视觉与模式识别 · 计算机科学 2025-11-18 Pengcheng Shi , Jiawei Chen , Jiaqi Liu , Xinglin Zhang , Tao Chen , Lei Li

Knowledge of mixtures' phase equilibria is crucial in nature and technical chemistry. Phase equilibria calculations of mixtures require activity coefficients. However, experimental data on activity coefficients is often limited due to high…

化学物理 · 物理学 2023-09-22 Benedikt Winter , Clemens Winter , Johannes Schilling , André Bardow

Endowing Large Multimodal Models (LMMs) with visual grounding capability can significantly enhance AIs' understanding of the visual world and their interaction with humans. However, existing methods typically fine-tune the parameters of…

计算机视觉与模式识别 · 计算机科学 2025-04-14 Size Wu , Sheng Jin , Wenwei Zhang , Lumin Xu , Wentao Liu , Wei Li , Chen Change Loy

Neural language models (LMs) are typically trained using only lexical features, such as surface forms of words. In this paper, we argue this deprives the LM of crucial syntactic signals that can be detected at high confidence using existing…

计算与语言 · 计算机科学 2018-03-13 Duncan Blythe , Alan Akbik , Roland Vollgraf

Semantic face editing has achieved substantial progress in recent years. Known as a growingly popular method, latent space manipulation performs face editing by changing the latent code of an input face to liberate users from painting…

计算机视觉与模式识别 · 计算机科学 2022-03-28 Wenjing Huang , Shikui Tu , Lei Xu

Large Language Models store extensive factual knowledge acquired during large-scale pre-training. However, this knowledge is inherently static, reflecting only the state of the world at the time of training. Knowledge editing has emerged as…

计算与语言 · 计算机科学 2025-10-14 Geunyeong Jeong , Juoh Sun , Seonghee Lee , Harksoo Kim

We introduce Sentence-level Language Modeling, a new pre-training objective for learning a discourse language representation in a fully self-supervised manner. Recent pre-training methods in NLP focus on learning either bottom or top-level…

计算与语言 · 计算机科学 2020-11-02 Haejun Lee , Drew A. Hudson , Kangwook Lee , Christopher D. Manning

Knowledge editing aims to change language models' performance on several special cases (i.e., editing scope) by infusing the corresponding expected knowledge into them. With the recent advancements in large language models (LLMs), knowledge…

计算与语言 · 计算机科学 2024-05-31 Jiaan Wang , Yunlong Liang , Zengkui Sun , Yuxuan Cao , Jiarong Xu , Fandong Meng

Unsupervised methods are promising for abstractive text summarization in that the parallel corpora is not required. However, their performance is still far from being satisfied, therefore research on promising solutions is on-going. In this…

计算与语言 · 计算机科学 2020-10-12 Ryosuke Kohita , Akifumi Wachi , Yang Zhao , Ryuki Tachibana

Semantic identifier (ID) is an important concept in information retrieval that aims to preserve the semantics of objects such as documents and items inside their IDs. Previous studies typically adopt a two-stage pipeline to learn semantic…

Language Models (LMs) struggle with linguistic understanding at the discourse level, even though discourse patterns such as coherence, cohesion, and narrative flow are prevalent in their pre-training data. To improve the discourse…

计算与语言 · 计算机科学 2026-02-17 Zachary Bamberger , Ofek Glick , Chaim Baskin , Yonatan Belinkov

Lifelong learning enables large language models (LLMs) to adapt to evolving information by continually updating their internal knowledge. An ideal system should support efficient, wide-ranging updates while preserving existing capabilities…

计算与语言 · 计算机科学 2026-03-11 Xiaojie Gu , Ziying Huang , Jia-Chen Gu , Kai Zhang

Neural implicit representations of 3D shapes have shown great potential in 3D shape editing due to their ability to model high-level semantics and continuous geometric representations. However, existing methods often suffer from limited…

图形学 · 计算机科学 2025-12-05 Jin Zhou , Hongliang Yang , Pengfei Xu , Hui Huang

Small Language Models (SLMs) have gained substantial attention due to their ability to execute diverse language tasks successfully while using fewer computer resources. These models are particularly ideal for deployment in limited…

计算与语言 · 计算机科学 2025-05-30 Tanjil Hasan Sakib , Md. Tanzib Hosain , Md. Kishor Morol

We propose Seq2Edits, an open-vocabulary approach to sequence editing for natural language processing (NLP) tasks with a high degree of overlap between input and output texts. In this approach, each sequence-to-sequence transduction is…

计算与语言 · 计算机科学 2020-09-24 Felix Stahlberg , Shankar Kumar

We introduce MIM (Masked Image Modeling)-Refiner, a contrastive learning boost for pre-trained MIM models. MIM-Refiner is motivated by the insight that strong representations within MIM models generally reside in intermediate layers.…

计算机视觉与模式识别 · 计算机科学 2025-02-24 Benedikt Alkin , Lukas Miklautz , Sepp Hochreiter , Johannes Brandstetter