相关论文: SMI-Editor: Edit-based SMILES Language Model with …

Masked image modeling (MIM) with transformer backbones has recently been exploited as a powerful self-supervised pre-training technique. The existing MIM methods adopt the strategy to mask random patches of the image and reconstruct the…

Language models demonstrate fundamental abilities in syntax, semantics, and reasoning, though their performance often depends significantly on the inputs they process. This study introduces TSIS (Simplified TSID) and its variants:TSISD…

Recent advances in large language models (LLMs) have demonstrated transformative potential across diverse fields. While LLMs have been applied to molecular simplified molecular input line entry system (SMILES) in computer-aided synthesis…

In vision-language pre-training (VLP), masked image modeling (MIM) has recently been introduced for fine-grained cross-modal alignment. However, in most existing methods, the reconstruction targets for MIM lack high-level semantics, and…

Pre-trained language models (PLMs) like BERT are being used for almost all language-related tasks, but interpreting their behavior still remains a significant challenge and many important questions remain largely unanswered. In this work,…

Therapeutic peptides have emerged as a pivotal modality in modern drug discovery, occupying a chemically and topologically rich space. While accurate prediction of their physicochemical properties is essential for accelerating peptide…

We study the ability of transformer-based language models (LMs) to understand social media language. Social media (SM) language is distinct from standard written language, yet existing benchmarks fall short of capturing LM performance in…

Deep generative models have recently been applied to molecule design. If the molecules are encoded in linear SMILES strings, modeling becomes convenient. However, models relying on string representations tend to generate invalid samples and…

Both masked image modeling (MIM) and natural language supervision have facilitated the progress of transferable visual pre-training. In this work, we seek the synergy between two paradigms and study the emerging properties when MIM meets…

Language models for molecular design have scaled to hundreds of millions of parameters, yet how they learn chemical grammar is poorly understood. We train SMolLM, a 53K-parameter weight-shared transformer, to generate novel SMILES with 95%…

Pre-trained language models (PrLM) have to carefully manage input units when training on a very large text with a vocabulary consisting of millions of words. Previous works have shown that incorporating span-level information over…

Recent advances in AI-generated content (AIGC) have significantly accelerated image editing techniques, driving increasing demand for diverse and fine-grained edits. Despite these advances, existing image editing methods still face…

Model editing aims at selectively updating a small subset of a neural model's parameters with an interpretable strategy to achieve desired modifications. It can significantly reduce computational costs to adapt to large language models…

Within this work, we introduce LIMIS: The first purely language-based interactive medical image segmentation model. We achieve this by adapting Grounded SAM to the medical domain and designing a language-based model interaction strategy…

Text-driven image editing has advanced rapidly, but reliably localizing these manipulations requires image manipulation localization (IML) models trained on large pixel-annotated datasets, and there is still no low-cost way to obtain such…

Large Language Models (LLMs) have shown extraordinary capabilities in understanding and generating text that closely mirrors human communication. However, a primary limitation lies in the significant computational demands during training,…

Synthesis planning and reaction outcome prediction are two fundamental problems in computer-aided organic chemistry for which a variety of data-driven approaches have emerged. Natural language approaches that model each problem as a…

Molecule generation is key to drug discovery and materials science, enabling the design of novel compounds with specific properties. Large language models (LLMs) can learn to perform a wide range of tasks from just a few examples. However,…

Language model pre-training has shown promising results in various downstream tasks. In this context, we introduce a cross-modal pre-trained language model, called Speech-Text BERT (ST-BERT), to tackle end-to-end spoken language…

We introduce Similarity-Distance-Magnitude (SDM) language models (LMs), which are sequence prediction models fine-tuned to maximize the proportion of generations in the well-calibrated, high-probability region partitioned by a final-layer…