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Traumatic brain injury (TBI) is a complex injury that is hard to predict and diagnose, with many studies focused on associating head kinematics to brain injury risk. Recently, there has been a push towards using computationally expensive…

Brain tissue deformation resulting from head impacts is primarily caused by rotation and can lead to traumatic brain injury. To quantify brain injury risk based on measurements of kinematics on the head, finite element (FE) models and…

Impact induced traumatic brain injury (ITBI) describes brain injury from head impact not necessarily accompanied by skull fracture. For sufficiently abrupt head impact decelerations, ITBI results from brain tissue stress incurred as the…

医学物理 · 物理学 2009-04-21 Eric G. Blackman

Research in blast-induced lung injury resulted in exposure thresholds that are useful in understanding and protecting humans from such injury. Because traumatic brain injury (TBI) due to blast exposure has become a prominent medical and…

医学物理 · 物理学 2011-02-09 Michael Courtney , Amy Courtney

Mild traumatic brain injury (mTBI, also known as concussion) caused by the head impact is a crucial global public health problem, but the physics of mTBI is still unclear. During the impact, the rapid movement of the head injures the brain,…

Objective: Head impact information including impact directions, speeds and force are important to study traumatic brain injury, design and evaluate protective gears. This study presents a deep learning model developed to accurately predict…

Traumatic brain injury can be caused by various types of head impacts. However, due to different kinematic characteristics, many brain injury risk estimation models are not generalizable across the variety of impacts that humans may…

Objective: Many recent studies have suggested that brain deformation resulting from a head impact is linked to the corresponding clinical outcome, such as mild traumatic brain injury (mTBI). Even though several finite element (FE) head…

Mild Traumatic Brain Injuries (mTBI) are caused by violent head motions or impacts. Most mTBI prevention strategies explicitly or implicitly rely on a "brain injury criterion". A brain injury criterion takes some descriptor of the head's…

医学物理 · 物理学 2022-01-19 Yang Wan , Alice Lux Fawzi , Haneesh Kesari

Traumatic brain injury (TBI) occurs when local mechanical load exceeds certain tolerance levels for brain tissue. Extensive research has been done previously for brain matter experiencing compression at quasistatic loading; however, limited…

生物物理 · 物理学 2013-02-20 Badar Rashid , Michel Destrade , Michael Gilchrist

Purpose: Computational head models are essential tools for studying the risk of mild traumatic brain injury (mTBI) under different activities and across populations. However, different computational models incorporate varied levels of…

组织与器官 · 定量生物学 2025-11-07 Anu Tripathi , Alison Brooks , Traci Snedden , Peter Ferrazzano , Christian Franck , Rika Wright Carlsen

Head motion induced by impacts has been deemed as one of the most important measures in brain injury prediction, given that the majority of brain injury metrics use head kinematics as input. Recently, researchers have focused on using fast…

定量方法 · 定量生物学 2020-12-11 Patricio Arrue , Nima Toosizadeh , Hessam Babaee , Kaveh Laksari

Traumatic brain injury [TBI] has become a signature injury of current military conflicts, with debilitating, costly, and long-lasting effects. Although mechanisms by which head impacts cause TBI have been well-researched, the mechanisms by…

医学物理 · 物理学 2017-03-08 William C. Moss , Michael J. King , Eric G. Blackman

The accurate prognosis for traumatic brain injury (TBI) patients is difficult yet essential to inform therapy, patient management, and long-term after-care. Patient characteristics such as age, motor and pupil responsiveness, hypoxia and…

It has long been suggested that neck muscle strength and anticipatory cocontraction can decrease head motions during head impacts. Here, we quantify the relative angular impulse contributions of neck soft tissue to head stabilization using…

组织与器官 · 定量生物学 2025-10-08 Calvin Kuo , Jodie Sheffels , Michael Fanton , Ina Bianca Yu , Rosa Hamalainen , David Camarillo

Anticipating changes to vehicle interiors with future automated driving systems, the automobile industry recently has focused attention on crash response in relaxed postures with increased seatback recline. Prior research found that this…

Background: Ventilator-associated pneumonia (VAP) in traumatic brain injury (TBI) patients poses a significant mortality risk and imposes a considerable financial burden on patients and healthcare systems. Timely detection and…

机器学习 · 计算机科学 2024-08-05 Negin Ashrafi , Armin Abdollahi , Maryam Pishgar

Objective: Traumatic brain injury can be caused by head impacts, but many brain injury risk estimation models are not equally accurate across the variety of impacts that patients may undergo and the characteristics of different types of…

Brain injuries are a major reason for mortality and morbidity following trauma in sports, work and traffic. Apart from the trauma at the site of impact (coup injury), other regions of the brain remote from the impact locations (non-coup)…

定量方法 · 定量生物学 2020-12-02 Rajesh Kumar , Md Zubair , Sudipto Mukherjee , Jacobo Antona Makoshi

Concussion and repeated exposure to mild traumatic brain injury are risks for athletes in many sports. While direct head impacts are analyzed to improve the detection and awareness of head acceleration events so that an athlete's brain…

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