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Recent work on aspect-level sentiment classification has demonstrated the efficacy of incorporating syntactic structures such as dependency trees with graph neural networks(GNN), but these approaches are usually vulnerable to parsing…

计算与语言 · 计算机科学 2021-03-23 Xiaochen Hou , Peng Qi , Guangtao Wang , Rex Ying , Jing Huang , Xiaodong He , Bowen Zhou

Spatial transcriptomics (ST) enables mapping gene expression with spatial context but is severely affected by high sparsity and technical noise, which conceals true biological signals and hinders downstream analyses. To address these…

机器学习 · 计算机科学 2026-03-10 Sayeem Bin Zaman , Fahim Hafiz , Riasat Azim

Aiming at the limitations of traditional medical decision system in processing large-scale heterogeneous medical data and realizing highly personalized recommendation, this paper introduces a personalized medical decision algorithm…

机器学习 · 计算机科学 2024-05-29 Yafeng Yan , Shuyao He , Zhou Yu , Jiajie Yuan , Ziang Liu , Yan Chen

We propose a Graph Neural Network (GNN)-based approach for Handwritten Mathematical Expression (HME) recognition by modeling HMEs as graphs, where nodes represent symbols and edges capture spatial dependencies. A deep BLSTM network is used…

计算机视觉与模式识别 · 计算机科学 2025-11-05 Cuong Tuan Nguyen , Ngoc Tuan Nguyen , Triet Hoang Minh Dao , Huy Minh Nhat , Huy Truong Dinh

Many real-world graphs (networks) are heterogeneous with different types of nodes and edges. Heterogeneous graph embedding, aiming at learning the low-dimensional node representations of a heterogeneous graph, is vital for various…

社会与信息网络 · 计算机科学 2021-12-15 Wentao Xu , Yingce Xia , Weiqing Liu , Jiang Bian , Jian Yin , Tie-Yan Liu

Spatial transcriptomics (ST) enables spatially resolved gene profiling but remains expensive and low-throughput, limiting large-cohort studies and routine clinical use. Predicting spatial gene expression from routine hematoxylin and eosin…

计算机视觉与模式识别 · 计算机科学 2026-04-24 Changfan Wang , Xinran Wang , Donghai Liu , Fei Su , Lulu Sun , Zhicheng Zhao , Zhu Meng

Feature selection, as a critical pre-processing step for machine learning, aims at determining representative predictors from a high-dimensional feature space dataset to improve the prediction accuracy. However, the increase in feature…

机器学习 · 统计学 2020-11-16 Fatemeh Amini , Guiping Hu

Traditional Machine Learning (ML) methods require large amounts of data to perform well, limiting their applicability in sparse or incomplete scenarios and forcing the usage of additional synthetic data to improve the model training. To…

机器学习 · 计算机科学 2025-11-18 Rosario Napoli , Giovanni Lonia , Antonio Celesti , Massimo Villari , Maria Fazio

Understanding the dynamic processes of the glassy system continues to be challenging. Recent advances have shown the power of graph neural networks (GNNs) for determining the correlation between structure and dynamics in the glassy system.…

无序系统与神经网络 · 物理学 2023-10-18 Xiao Jiang , Zean Tian , Kenli Li

Recent advancements in spatial transcriptomics technologies allow researchers to simultaneously measure RNA expression levels for hundreds to thousands of genes while preserving spatial information within tissues, providing critical…

统计方法学 · 统计学 2025-07-31 Catherine Higgins , Jingyi Jessica Li , Michelle Carey

Employing graph neural networks (GNNs) for graph clustering has shown promising results in deep graph clustering. However, existing methods disregard the reciprocal relationship between representation learning and structure augmentation:…

机器学习 · 计算机科学 2026-05-19 Shifei Ding , Benyu Wu , Xiao Xu , Ling Ding , Xindong Wu

A common starting point for drug design is to find small chemical groups or "fragments" that form interactions with distinct subregions in a protein binding pocket. The subsequent challenge is to assemble these fragments into a molecule…

定量方法 · 定量生物学 2025-05-29 Rohan V. Koodli , Alexander S. Powers , Ayush Pandit , Chiho Im , Ron O. Dror

Graph Neural Networks (GNNs) have achieved notable success in the analysis of non-Euclidean data across a wide range of domains. However, their applicability is constrained by the dependence on the observed graph structure. To solve this…

机器学习 · 计算机科学 2024-09-19 Ziyan Wang , Yaxuan He , Bin Liu

Spatial transcriptomics (ST) is a groundbreaking genomic technology that enables spatial localization analysis of gene expression within tissue sections. However, it is significantly limited by high costs and sparse spatial resolution. An…

图像与视频处理 · 电气工程与系统科学 2024-07-31 Zhiceng Shi , Shuailin Xue , Fangfang Zhu , Wenwen Min

Predicting interactions between structured entities lies at the core of numerous tasks such as drug regimen and new material design. In recent years, graph neural networks have become attractive. They represent structured entities as graphs…

机器学习 · 计算机科学 2020-04-21 Nuo Xu , Pinghui Wang , Long Chen , Jing Tao , Junzhou Zhao

Graph Visualization, also known as Graph Drawing, aims to find geometric embeddings of graphs that optimize certain criteria. Stress is a widely used metric; stress is minimized when every pair of nodes is positioned at their shortest path…

计算几何 · 计算机科学 2024-02-13 Florian Grötschla , Joël Mathys , Robert Veres , Roger Wattenhofer

Understanding how cellular morphology, gene expression, and spatial context jointly shape tissue function is a central challenge in biology. Image-based spatial transcriptomics technologies now provide high-resolution measurements of cell…

定量方法 · 定量生物学 2026-02-17 Zhenglun Kong , Mufan Qiu , John Boesen , Xiang Lin , Sukwon Yun , Tianlong Chen , Manolis Kellis , Marinka Zitnik

Accurately predicting gene expression from histopathology images offers a scalable and non-invasive approach to molecular profiling, with significant implications for precision medicine and computational pathology. However, existing methods…

计算机视觉与模式识别 · 计算机科学 2025-12-09 Yaxuan Song , Jianan Fan , Hang Chang , Weidong Cai

The identification of cancer genes is a critical yet challenging problem in cancer genomics research. Existing computational methods, including deep graph neural networks, fail to exploit the multilayered gene-gene interactions or provide…

机器学习 · 计算机科学 2023-05-04 Michail Chatzianastasis , Michalis Vazirgiannis , Zijun Zhang

Graph neural networks are emerging as continuation of deep learning success w.r.t. graph data. Tens of different graph neural network variants have been proposed, most following a neighborhood aggregation scheme, where the node features are…

机器学习 · 计算机科学 2021-02-09 Dawei Leng , Jinjiang Guo , Lurong Pan , Jie Li , Xinyu Wang