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Medical image segmentation is evolving from task-specific models toward generalizable frameworks. Recent research leverages Multi-modal Large Language Models (MLLMs) as autonomous agents, employing reinforcement learning with verifiable…

计算机视觉与模式识别 · 计算机科学 2026-02-04 Shengyuan Liu , Liuxin Bao , Qi Yang , Wanting Geng , Boyun Zheng , Chenxin Li , Wenting Chen , Houwen Peng , Yixuan Yuan

Large Language Models (LLMs) are increasingly applied in healthcare, yet ensuring their ethical integrity and safety compliance remains a major barrier to clinical deployment. This work introduces a multi-agent refinement framework designed…

Clinical guidelines, typically structured as decision trees, are central to evidence-based medical practice and critical for ensuring safe and accurate diagnostic decision-making. However, it remains unclear whether Large Language Models…

计算与语言 · 计算机科学 2025-05-20 Xiaomin Li , Mingye Gao , Yuexing Hao , Taoran Li , Guangya Wan , Zihan Wang , Yijun Wang

Advancements in large language models (LLMs) allow them to address diverse questions using human-like interfaces. Still, limitations in their training prevent them from answering accurately in scenarios that could benefit from multiple…

人工智能 · 计算机科学 2025-04-09 Yoshitaka Inoue , Tianci Song , Xinling Wang , Augustin Luna , Tianfan Fu

Clinical diagnosis is a complex reasoning process in which clinicians gather evidence, form hypotheses, and test them against alternative explanations. In medical training, this reasoning is explicitly developed through counterfactual…

计算与语言 · 计算机科学 2026-04-24 Zhiwen You , Xi Chen , Aniket Vashishtha , Simo Du , Gabriel Erion-Barner , Hongyuan Mei , Hao Peng , Yue Guo

Large language models (LLMs) are increasingly envisioned as decision-support tools in clinical practice, yet safe clinical reasoning demands integrating heterogeneous knowledge bases -- trials, primary studies, regulatory documents, and…

It is becoming increasingly emphasis on the importance of LLM participating in clinical diagnosis decision-making. However, the low specialization refers to that current medical LLMs can not provide specific medical advice, which are more…

计算与语言 · 计算机科学 2023-12-06 Binbin Li , Tianxin Meng , Xiaoming Shi , Jie Zhai , Tong Ruan

Large Language Model (LLM)-based agents have demonstrated strong capabilities across a wide range of tasks, and their application in the medical domain holds particular promise due to the demand for high generalizability and reliance on…

人工智能 · 计算机科学 2025-08-18 Yangyang Zhuang , Wenjia Jiang , Jiayu Zhang , Ze Yang , Joey Tianyi Zhou , Chi Zhang

Multimodal large language models (MLLMs) have shown great potential in medical applications, yet existing benchmarks inadequately capture real-world clinical complexity. We introduce MEDSYN, a multilingual, multimodal benchmark of highly…

计算与语言 · 计算机科学 2026-04-20 Boqi Chen , Xudong Liu , Jiachuan Peng , Marianne Frey-Marti , Bang Zheng , Kyle Lam , Lin Li , Jianing Qiu

Large Language Models (LLMs) and multi-agent systems have shown impressive capabilities in natural language tasks but face challenges in clinical trial applications, primarily due to limited access to external knowledge. Recognizing the…

计算与语言 · 计算机科学 2024-07-23 Ling Yue , Sixue Xing , Jintai Chen , Tianfan Fu

Recent developments in Large Language Model (LLM)-based agents have shown impressive capabilities spanning multiple domains, exemplified by deep research systems that demonstrate superior performance on complex information-seeking and…

Background: Globally we face a projected shortage of 11 million healthcare practitioners by 2030, and administrative burden consumes 50% of clinical time. Artificial intelligence (AI) has the potential to help alleviate these problems.…

The recent success of Large Language Models (LLMs) has had a significant impact on the healthcare field, providing patients with medical advice, diagnostic information, and more. However, due to a lack of professional medical knowledge,…

计算与语言 · 计算机科学 2024-06-27 Wenya Xie , Qingying Xiao , Yu Zheng , Xidong Wang , Junying Chen , Ke Ji , Anningzhe Gao , Xiang Wan , Feng Jiang , Benyou Wang

Large language models (LLMs) show promise for clinical use. They are often evaluated using datasets such as MedQA. However, Many medical datasets, such as MedQA, rely on simplified Question-Answering (Q\A) that underrepresents real-world…

计算与语言 · 计算机科学 2025-10-24 Yunpeng Xiao , Carl Yang , Mark Mai , Xiao Hu , Kai Shu

Recent progress in Large Language Models (LLMs) has drawn attention to their potential for accelerating drug discovery. However, a central problem remains: translating theoretical ideas into robust implementations in the highly specialized…

机器学习 · 计算机科学 2025-03-06 Sizhe Liu , Yizhou Lu , Siyu Chen , Xiyang Hu , Jieyu Zhao , Yingzhou Lu , Yue Zhao

Proactive agents that anticipate user intentions without explicit prompts represent a significant evolution in human-AI interaction, promising to reduce cognitive load and streamline workflows. However, existing datasets suffer from two…

人机交互 · 计算机科学 2026-02-11 Yuanbo Tang , Huaze Tang , Tingyu Cao , Lam Nguyen , Anping Zhang , Xinwen Cao , Chunkang Liu , Wenbo Ding , Yang Li

LLMs have achieved significant performance progress in various NLP applications. However, LLMs still struggle to meet the strict requirements for accuracy and reliability in the medical field and face many challenges in clinical…

Recent advances in generative models, including large language models (LLMs), vision language models (VLMs), and diffusion models, have accelerated the field of natural language and image processing in medicine and marked a significant…

An effective healthcare agent must be able to recall and reason over a patient's longitudinal medical history. However, the absence of datasets with realistic long-term dialogue timelines limits systematic evaluation. Real clinical text is…

计算与语言 · 计算机科学 2026-05-20 Hebin Hu , Renke Dai , Ah-Hwee Tan , Yilin Kang

Recent advancements in medical Large Language Models (LLMs) have showcased their powerful reasoning and diagnostic capabilities. Despite their success, current unified multimodal medical LLMs face limitations in knowledge update costs,…

计算与语言 · 计算机科学 2025-06-25 Yucheng Zhou , Lingran Song , Jianbing Shen