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Most deep learning models in medical imaging are trained on adult data with unclear performance on pediatric images. In this work, we aim to address this challenge in the context of automated anatomy segmentation in whole-body Computed…

图像与视频处理 · 电气工程与系统科学 2024-04-23 Chih-Ying Liu , Jeya Maria Jose Valanarasu , Camila Gonzalez , Curtis Langlotz , Andrew Ng , Sergios Gatidis

Longitudinal imaging is capable of capturing the static ana\-to\-mi\-cal structures and the dynamic changes of the morphology resulting from aging or disease progression. Self-supervised learning allows to learn new representation from…

The widespread availability of electronic health records (EHRs) promises to usher in the era of personalized medicine. However, the problem of extracting useful clinical representations from longitudinal EHR data remains challenging. In…

机器学习 · 计算机科学 2017-01-27 Zhengping Che , Yu Cheng , Zhaonan Sun , Yan Liu

Numerous studies have established that estimated brain age, as derived from statistical models trained on healthy populations, constitutes a valuable biomarker that is predictive of cognitive decline and various neurological diseases. In…

计算机视觉与模式识别 · 计算机科学 2019-07-02 Xinyang Feng , Zachary C. Lipton , Jie Yang , Scott A. Small , Frank A. Provenzano

Ensuring the privacy of research participants is vital, even more so in healthcare environments. Deep learning approaches to neuroimaging require large datasets, and this often necessitates sharing data between multiple sites, which is…

定量方法 · 定量生物学 2021-06-04 Umang Gupta , Dimitris Stripelis , Pradeep K. Lam , Paul M. Thompson , José Luis Ambite , Greg Ver Steeg

In the rapidly evolving landscape of artificial intelligence, generative models such as Generative Adversarial Networks (GANs) and Diffusion Models have become cornerstone technologies, driving innovation in diverse fields from art creation…

机器学习 · 计算机科学 2024-08-01 Jack He , Jianxing Zhao , Andrew Bai , Cho-Jui Hsieh

The latest advances in computer-assisted precision medicine are making it feasible to move from population-wide models that are useful to discover aggregate patterns that hold for group-based analysis to patient-specific models that can…

计算机视觉与模式识别 · 计算机科学 2021-07-28 Da Ma , Vincent Chow , Karteek Popuri , Mirza Faisal Beg

Longitudinal MRIs are often used to capture the gradual deterioration of brain structure and function caused by aging or neurological diseases. Analyzing this data via machine learning generally requires a large number of ground-truth…

计算机视觉与模式识别 · 计算机科学 2021-06-21 Jiahong Ouyang , Qingyu Zhao , Ehsan Adeli , Edith V Sullivan , Adolf Pfefferbaum , Greg Zaharchuk , Kilian M Pohl

The traditional manual age estimation method is crucial labor based on many kinds of the X-Ray image. Some current studies have shown that lateral cephalometric(LC) images can be used to estimate age. However, these methods are based on…

图像与视频处理 · 电气工程与系统科学 2021-12-08 Ningtao Liu

Demographic attributes are universally present in electronic health records. They are the most widespread information across populations and diseases, and serve as vital predictors in clinical risk stratification and treatment decisions.…

机器学习 · 计算机科学 2025-10-15 Li-Chin Chen , Ji-Tian Sheu , Yuh-Jue Chuang

Purpose: Automated medical image-based prediction of clinical outcomes, such as overall survival (OS), has great potential in improving patient prognostics and personalized treatment planning. We developed a deep regression framework using…

Confounding pathology with normal anatomical variation remains a significant challenge in unsupervised medical-image anomaly detection, resulting in numerous false positives. To enhance integration of healthy variation, we augment the…

定量方法 · 定量生物学 2026-03-09 P. Bilha Githinji , Xi Yuan , Ijaz Gul , Lian Zhang , Jinhao Xu , Zhenglin Chen , Peiwu Qin , Dongmei Yu

Usually, lesions are not isolated but are associated with the surrounding tissues. For example, the growth of a tumour can depend on or infiltrate into the surrounding tissues. Due to the pathological nature of the lesions, it is…

图像与视频处理 · 电气工程与系统科学 2022-10-12 Lin Wang , Xiufen Ye , Donghao Zhang , Wanji He , Lie Ju , Yi Luo , Huan Luo , Xin Wang , Wei Feng , Kaimin Song , Xin Zhao , Zongyuan Ge

Radiomics is an active area of research focusing on high throughput feature extraction from medical images with a wide array of applications in clinical practice, such as clinical decision support in oncology. However, noise in low dose…

定量方法 · 定量生物学 2021-09-07 Junhua Chen , Inigo Bermejo , Andre Dekker , Leonard Wee

We address the problem of fitting 3D human models to 3D scans of dressed humans. Classical methods optimize both the data-to-model correspondences and the human model parameters (pose and shape), but are reliable only when initialized close…

计算机视觉与模式识别 · 计算机科学 2021-11-29 Bharat Lal Bhatnagar , Cristian Sminchisescu , Christian Theobalt , Gerard Pons-Moll

Recently, it has become progressively more evident that classic diagnostic labels are unable to reliably describe the complexity and variability of several clinical phenotypes. This is particularly true for a broad range of neuropsychiatric…

机器学习 · 计算机科学 2024-02-28 Giovanna Maria Dimitri , Simeon Spasov , Andrea Duggento , Luca Passamonti , Pietro Li`o , Nicola Toschi

Deep neural networks can be effective means to automatically classify aerial images but is easy to overfit to the training data. It is critical for trained neural networks to be robust to variations that exist between training and test…

计算机视觉与模式识别 · 计算机科学 2019-09-25 Jiayun Wang , Patrick Virtue , Stella X. Yu

While unsupervised variational autoencoders (VAE) have become a powerful tool in neuroimage analysis, their application to supervised learning is under-explored. We aim to close this gap by proposing a unified probabilistic model for…

机器学习 · 计算机科学 2019-07-15 Qingyu Zhao , Ehsan Adeli , Nicolas Honnorat , Tuo Leng , Kilian M. Pohl

Understanding the internal physiological changes accompanying the aging process is an important aspect of medical image interpretation, with the expected changes acting as a baseline when reporting abnormal findings. Deep learning has…

图像与视频处理 · 电气工程与系统科学 2022-07-05 Matthew MacPherson , Keerthini Muthuswamy , Ashik Amlani , Charles Hutchinson , Vicky Goh , Giovanni Montana

Deep learning (DL) methods are increasingly outperforming classical approaches in brain imaging, yet their generalizability across diverse imaging cohorts remains inadequately assessed. As age and sex are key neurobiological markers in…