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Prediction for ADMET (Absorption, Distribution, Metabolism, Excretion, and Toxicity) plays a crucial role in drug discovery and development, accelerating the screening and optimization of new drugs. Existing methods primarily rely on…

机器学习 · 计算机科学 2025-09-08 Han Zhang , Fengji Ma , Jiamin Su , Xinyue Yang , Lei Wang , Wen-Cai Ye , Li Liu

Model merging-based multitask learning (MTL) offers a promising approach for performing MTL by merging multiple expert models without requiring access to raw training data. However, in this paper, we examine the merged model's…

机器学习 · 计算机科学 2024-10-21 Enneng Yang , Li Shen , Zhenyi Wang , Guibing Guo , Xingwei Wang , Xiaocun Cao , Jie Zhang , Dacheng Tao

We evaluated the temporal performance of a deep learning (DL) based artificial intelligence (AI) model for auto segmentation in prostate radiotherapy, seeking to correlate its efficacy with changes in clinical landscapes. Our study involved…

图像与视频处理 · 电气工程与系统科学 2023-11-17 Biling Wang , Michael Dohopolski , Ti Bai , Junjie Wu , Raquibul Hannan , Neil Desai , Aurelie Garant , Daniel Yang , Dan Nguyen , Mu-Han Lin , Robert Timmerman , Xinlei Wang , Steve Jiang

When faced with learning a set of inter-related tasks from a limited amount of usable data, learning each task independently may lead to poor generalization performance. Multi-Task Learning (MTL) exploits the latent relations between tasks…

机器学习 · 计算机科学 2015-08-14 Niloofar Yousefi , Michael Georgiopoulos , Georgios C. Anagnostopoulos

Machine learning shows great potential in virtual screening for drug discovery. Current efforts on accelerating docking-based virtual screening do not consider using existing data of other previously developed targets. To make use of the…

机器学习 · 计算机科学 2021-12-14 Zijing Liu , Xianbin Ye , Xiaomin Fang , Fan Wang , Hua Wu , Haifeng Wang

Many real-world large-scale regression problems can be formulated as Multi-task Learning (MTL) problems with a massive number of tasks, as in retail and transportation domains. However, existing MTL methods still fail to offer both the…

机器学习 · 计算机科学 2018-11-15 Xiao He , Francesco Alesiani , Ammar Shaker

Predicting attributes in the landmark free facial images is itself a challenging task which gets further complicated when the face gets occluded due to the usage of masks. Smart access control gates which utilize identity verification or…

计算机视觉与模式识别 · 计算机科学 2022-01-12 Prerana Mukherjee , Vinay Kaushik , Ronak Gupta , Ritika Jha , Daneshwari Kankanwadi , Brejesh Lall

We previously proposed an intelligent automatic treatment planning framework for radiotherapy, in which a virtual treatment planner network (VTPN) was built using deep reinforcement learning (DRL) to operate a treatment planning system…

医学物理 · 物理学 2021-06-09 Chenyang Shen , Liyuan Chen , Yesenia Gonzalez , Xun Jia

Multi-task learning (MTL) paradigm focuses on jointly learning two or more tasks, aiming for significant improvement w.r.t model's generalizability, performance, and training/inference memory footprint. The aforementioned benefits become…

计算机视觉与模式识别 · 计算机科学 2022-10-27 Nitin Bansal , Pan Ji , Junsong Yuan , Yi Xu

Deep learning (DL) 3D dose prediction has recently gained a lot of attention. However, the variability of plan quality in the training dataset, generated manually by planners with wide range of expertise, can dramatically effect the quality…

计算机视觉与模式识别 · 计算机科学 2021-06-08 Navdeep Dahiya , Gourav Jhanwar , Anthony Yezzi , Masoud Zarepisheh , Saad Nadeem

Proton pencil beam scanning (PBS) treatment planning for head and neck (H&N) cancers is a time-consuming and experience-demanding task where a large number of planning objectives are involved. Deep reinforcement learning (DRL) has recently…

定量方法 · 定量生物学 2024-09-19 Qingqing Wang , Chang Chang

Many real-world datasets are labeled with natural orders, i.e., ordinal labels. Ordinal regression is a method to predict ordinal labels that finds a wide range of applications in data-rich domains, such as natural, health and social…

机器学习 · 计算机科学 2020-04-28 Lu Wang , Dongxiao Zhu

Multi-Task Learning (MTL) aims to enhance the model generalization by sharing representations between related tasks for better performance. Typical MTL methods are jointly trained with the complete multitude of ground-truths for all tasks…

计算机视觉与模式识别 · 计算机科学 2021-10-15 Yufeng Wang , Yi-Hsuan Tsai , Wei-Chih Hung , Wenrui Ding , Shuo Liu , Ming-Hsuan Yang

Typical multi-task learning (MTL) methods rely on architectural adjustments and a large trainable parameter set to jointly optimize over several tasks. However, when the number of tasks increases so do the complexity of the architectural…

计算机视觉与模式识别 · 计算机科学 2019-03-29 Gjorgji Strezoski , Nanne van Noord , Marcel Worring

Motivation: Tumor classification using Imaging Mass Spectrometry (IMS) data has a high potential for future applications in pathology. Due to the complexity and size of the data, automated feature extraction and classification steps are…

Organ transplant is the essential treatment method for some end-stage diseases, such as liver failure. Analyzing the post-transplant cause of death (CoD) after organ transplant provides a powerful tool for clinical decision making,…

机器学习 · 计算机科学 2023-10-09 Sirui Ding , Qiaoyu Tan , Chia-yuan Chang , Na Zou , Kai Zhang , Nathan R. Hoot , Xiaoqian Jiang , Xia Hu

Multi-task learning (MTL) is a powerful machine learning paradigm designed to leverage shared knowledge across tasks to improve generalization and performance. Previous works have proposed approaches to MTL that can be divided into feature…

机器学习 · 计算机科学 2024-06-13 Paolo Bonetti , Alberto Maria Metelli , Marcello Restelli

Multi-task learning (MTL) optimizes several learning tasks simultaneously and leverages their shared information to improve generalization and the prediction of the model for each task. Auxiliary tasks can be added to the main task to…

机器学习 · 计算机科学 2020-07-03 Partoo Vafaeikia , Khashayar Namdar , Farzad Khalvati

Human visual attention has recently shown its distinct capability in boosting machine learning models. However, studies that aim to facilitate medical tasks with human visual attention are still scarce. To support the use of visual…

图像与视频处理 · 电气工程与系统科学 2022-02-16 Hongzhi Zhu , Robert Rohling , Septimiu Salcudean

Multi-task learning (MTL) concurrently trains a model on diverse task datasets to exploit common features, thereby improving overall performance across the tasks. Recent studies have dedicated efforts to merging multiple independent model…

机器学习 · 计算机科学 2025-06-16 Bingjie Zhang , Hongkang Li , Changlong Shi , Guowei Rong , He Zhao , Dongsheng Wang , Dandan Guo , Meng Wang