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Pathological captioning of Whole Slide Images (WSIs), though is essential in computer-aided pathological diagnosis, has rarely been studied due to the limitations in datasets and model training efficacy. In this paper, we propose a new…

计算机视觉与模式识别 · 计算机科学 2023-11-01 Wenkang Qin , Rui Xu , Peixiang Huang , Xiaomin Wu , Heyu Zhang , Lin Luo

Whole Slide Imaging (WSI), which involves high-resolution digital scans of pathology slides, has become the gold standard for cancer diagnosis, but its gigapixel resolution and the scarcity of annotated datasets present challenges for deep…

图像与视频处理 · 电气工程与系统科学 2025-02-03 Rita Pereira , M. Rita Verdelho , Catarina Barata , Carlos Santiago

While Multiple Instance Learning (MIL) has shown promising results in digital Pathology Whole Slide Image (WSI) classification, such a paradigm still faces performance and generalization problems due to challenges in high computational…

计算机视觉与模式识别 · 计算机科学 2023-03-16 Honglin Li , Chenglu Zhu , Yunlong Zhang , Yuxuan Sun , Zhongyi Shui , Wenwei Kuang , Sunyi Zheng , Lin Yang

Interpretability is significant in computational pathology, leading to the development of multimodal information integration from histopathological image and corresponding text data.However, existing multimodal methods have limited…

计算机视觉与模式识别 · 计算机科学 2026-01-22 Kangcheng Zhou , Jun Jiang , Qing Zhang , Shuang Zheng , Qingli Li , Shugong Xu

In Computational Pathology (CPath), the introduction of Vision-Language Models (VLMs) has opened new avenues for research, focusing primarily on aligning image-text pairs at a single magnification level. However, this approach might not be…

Whole slide image (WSI) assessment is a challenging and crucial step in cancer diagnosis and treatment planning. WSIs require high magnifications to facilitate sub-cellular analysis. Precise annotations for patch- or even pixel-level…

计算机视觉与模式识别 · 计算机科学 2023-11-20 Simon Holdenried-Krafft , Peter Somers , Ivonne A. Montes-Majarro , Diana Silimon , Cristina Tarín , Falko Fend , Hendrik P. A. Lensch

Prompt learning has emerged as a promising paradigm for adapting pre-trained vision-language models (VLMs) to few-shot whole slide image (WSI) classification by aligning visual features with textual representations, thereby reducing…

计算机视觉与模式识别 · 计算机科学 2025-10-01 Junjie Zhou , Wei Shao , Yagao Yue , Wei Mu , Peng Wan , Qi Zhu , Daoqiang Zhang

While Large Language Models (LLMs) are emerging as a promising direction in computational pathology, the substantial computational cost of giga-pixel Whole Slide Images (WSIs) necessitates the use of Multi-Instance Learning (MIL) to enable…

计算机视觉与模式识别 · 计算机科学 2025-11-12 Zhenfeng Zhuang , Fangyu Zhou , Liansheng Wang

Histopathology Whole-Slide Images (WSIs) provide an important tool to assess cancer prognosis in computational pathology (CPATH). While existing survival analysis (SA) approaches have made exciting progress, they are generally limited to…

计算机视觉与模式识别 · 计算机科学 2025-02-12 Pei Liu , Luping Ji , Jiaxiang Gou , Bo Fu , Mao Ye

Whole slide imaging is routinely adopted for carcinoma diagnosis and prognosis. Abundant experience is required for pathologists to achieve accurate and reliable diagnostic results of whole slide images (WSI). The huge size and…

计算机视觉与模式识别 · 计算机科学 2024-07-09 Pingyi Chen , Chenglu Zhu , Sunyi Zheng , Honglin Li , Lin Yang

With the development of digital imaging in medical microscopy, artificial intelligent-based analysis of pathological whole slide images (WSIs) provides a powerful tool for cancer diagnosis. Limited by the expensive cost of pixel-level…

计算机视觉与模式识别 · 计算机科学 2024-11-19 Jiawen Li , Qiehe Sun , Renao Yan , Yizhi Wang , Yuqiu Fu , Yani Wei , Tian Guan , Huijuan Shi , Yonghonghe He , Anjia Han

Multiple Instance Learning (MIL) plays a significant role in computational pathology, enabling weakly supervised analysis of Whole Slide Image (WSI) datasets. The field of WSI analysis is confronted with a severe long-tailed distribution…

计算机视觉与模式识别 · 计算机科学 2025-03-04 Xitong Ling , Yifeng Ping , Jiawen Li , Jing Peng , Yuxuan Chen , Minxi Ouyang , Yizhi Wang , Yonghong He , Tian Guan , Xiaoping Liu , Lianghui Zhu

Multiple Instance Learning (MIL) has emerged as the best solution for Whole Slide Image (WSI) classification. It consists of dividing each slide into patches, which are treated as a bag of instances labeled with a global label. MIL includes…

计算机视觉与模式识别 · 计算机科学 2025-05-05 Ali Mammadov , Loic Le Folgoc , Julien Adam , Anne Buronfosse , Gilles Hayem , Guillaume Hocquet , Pietro Gori

We address the challenging problem of whole slide image (WSI) classification. WSIs have very high resolutions and usually lack localized annotations. WSI classification can be cast as a multiple instance learning (MIL) problem when only…

计算机视觉与模式识别 · 计算机科学 2021-04-05 Bin Li , Yin Li , Kevin W. Eliceiri

Whole slide imaging (WSI) has transformed digital pathology by enabling computational analysis of gigapixel histopathology images. Recent foundation model advances have accelerated progress in computational pathology, facilitating joint…

计算机视觉与模式识别 · 计算机科学 2026-03-20 Peihang Wu , Zehong Chen , Lijian Xu

Whole Slide Images (WSIs) in histopathology pose a significant challenge for extensive medical image analysis due to their ultra-high resolution, massive scale, and intricate spatial relationships. Although existing Multiple Instance…

计算机视觉与模式识别 · 计算机科学 2025-08-05 Jiaxuan Lu , Yuhui Lin , Junyan Shi , Fang Yan , Dongzhan Zhou , Yue Gao , Xiaosong Wang

Whole slide image (WSI) classification is a critical task in computational pathology, requiring the processing of gigapixel-sized images, which is challenging for current deep-learning methods. Current state of the art methods are based on…

计算机视觉与模式识别 · 计算机科学 2023-10-06 Jingwei Zhang , Saarthak Kapse , Ke Ma , Prateek Prasanna , Joel Saltz , Maria Vakalopoulou , Dimitris Samaras

In digital pathology, whole slide images (WSIs) are widely used for applications such as cancer diagnosis and prognosis prediction. Visual transformer models have recently emerged as a promising method for encoding large regions of WSIs…

计算机视觉与模式识别 · 计算机科学 2023-04-18 Shuai Jiang , Liesbeth Hondelink , Arief A. Suriawinata , Saeed Hassanpour

Whole slide images (WSIs) in computational pathology (CPath) pose a major computational challenge due to their gigapixel scale, often requiring the processing of tens to hundreds of thousands of high-resolution patches per slide. This…

计算机视觉与模式识别 · 计算机科学 2025-08-21 Yonghan Shin , SeungKyu Kim , Won-Ki Jeong

Segmenting tumors in histological images is vital for cancer diagnosis. While fully supervised models excel with pixel-level annotations, creating such annotations is labor-intensive and costly. Accurate histopathology image segmentation…

计算机视觉与模式识别 · 计算机科学 2024-07-16 Yinsheng He , Xingyu Li , Roger J. Zemp