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Goal-oriented de novo molecule design, namely generating molecules with specific property or substructure constraints, is a crucial yet challenging task in drug discovery. Existing methods, such as Bayesian optimization and reinforcement…

计算工程、金融与科学 · 计算机科学 2025-02-28 Chuanliu Fan , Ziqiang Cao , Zicheng Ma , Nan Yu , Yimin Peng , Jun Zhang , Yiqin Gao , Guohong Fu

Large language models (LLMs) have revolutionized natural language processing (NLP), yet open-source multilingual LLMs remain scarce, with existing models often limited in language coverage. Such models typically prioritize well-resourced…

Fine-grained multimodal capability in Multimodal Large Language Models (MLLMs) has emerged as a critical research direction, particularly for tackling the visual grounding (VG) problem. Despite the strong performance achieved by existing…

计算机视觉与模式识别 · 计算机科学 2025-08-21 Weitai Kang , Weiming Zhuang , Zhizhong Li , Yan Yan , Lingjuan Lyu

Recently, Large Language Models (LLMs) and Multimodal Large Language Models (MLLMs) have shown promise in instruction following and 2D image understanding. While these models are powerful, they have not yet been developed to comprehend the…

计算机视觉与模式识别 · 计算机科学 2023-12-22 Senqiao Yang , Jiaming Liu , Ray Zhang , Mingjie Pan , Zoey Guo , Xiaoqi Li , Zehui Chen , Peng Gao , Yandong Guo , Shanghang Zhang

Large Language Models (LLMs) can enhance analytics systems with powerful data summarization, cleaning, and semantic transformation capabilities. However, deploying LLMs at scale -- processing millions to billions of rows -- remains…

数据库 · 计算机科学 2025-07-08 Bardia Mohammadi , Laurent Bindschaedler

Large Language Models (LLMs) have achieved remarkable success but face significant computational and memory challenges, particularly due to their extensive output vocabularies. The final linear projection layer, mapping hidden states to…

计算与语言 · 计算机科学 2025-05-16 Jintian Shao , Hongyi Huang , Jiayi Wu , YiMing Cheng , ZhiYu Wu , You Shan , MingKai Zheng

Large Language Models (LLMs) have shown impressive versatility as general purpose models. However, their broad applicability comes at a high-cost computational overhead, particularly in auto-regressive decoding where each step requires a…

计算与语言 · 计算机科学 2025-08-04 Itay Nakash , Nitay Calderon , Eyal Ben David , Elad Hoffer , Roi Reichart

Memory-efficient backpropagation (MeBP) has enabled first-order fine-tuning of large language models (LLMs) on mobile devices with less than 1GB memory. However, MeBP requires backward computation through all transformer layers at every…

机器学习 · 计算机科学 2026-02-16 Juneyoung Park , Eunbeen Yoon , Seongwan Kim. Jaeho Lee

Language models (LMs) have demonstrated expert-level reasoning and recall abilities in medicine. However, computational costs and privacy concerns are mounting barriers to wide-scale implementation. To address these significant limitations,…

计算与语言 · 计算机科学 2025-12-01 Krithik Vishwanath , Jaden Stryker , Anton Alyakin , Daniel Alexander Alber , Eric Karl Oermann

Bytes form the basis of the digital world and thus are a promising building block for multimodal foundation models. Recently, Byte Language Models (BLMs) have emerged to overcome tokenization, yet the excessive length of bytestreams…

计算与语言 · 计算机科学 2025-02-21 Eric Egli , Matteo Manica , Jannis Born

Vision-Language Models (VLMs) trained on web-scale corpora excel at natural image tasks and are increasingly repurposed for healthcare; however, their competence in medical tasks remains underexplored. We present a comprehensive evaluation…

计算机视觉与模式识别 · 计算机科学 2025-07-21 Che Liu , Jiazhen Pan , Weixiang Shen , Wenjia Bai , Daniel Rueckert , Rossella Arcucci

With the emergence of Large Language Models (LLMs) and Vision Foundation Models (VFMs), multimodal AI systems benefiting from large models have the potential to equally perceive the real world, make decisions, and control tools as humans.…

The advent of large vision-language models (LVLMs) represents a remarkable advance in the quest for artificial general intelligence. However, the model's effectiveness in both specialized and general tasks warrants further investigation.…

计算机视觉与模式识别 · 计算机科学 2024-10-29 Yao Jiang , Xinyu Yan , Ge-Peng Ji , Keren Fu , Meijun Sun , Huan Xiong , Deng-Ping Fan , Fahad Shahbaz Khan

The rapid development of large language models (LLM) has greatly enhanced everyday applications. While many FPGA-based accelerators, with flexibility for fine-grained data control, exhibit superior speed and energy efficiency compared to…

硬件体系结构 · 计算机科学 2026-03-24 Zifan He , Shengyu Ye , Rui Ma , Yang Wang , Jason Cong

Recent advances in multimodal large language models (MLLMs) have enabled impressive progress in vision-language understanding, yet their high computational cost limits deployment in resource-constrained scenarios such as personal…

计算机视觉与模式识别 · 计算机科学 2026-04-08 Quoc-Huy Trinh , Mustapha Abdullahi , Bo Zhao , Debesh Jha

Large Language Models (LLMs) have demonstrated significant promise in automating software development tasks, yet their capabilities with respect to software design tasks remains largely unclear. This study investigates the capabilities of…

软件工程 · 计算机科学 2025-03-11 L. P. Franciscatto Guerra , N. Ernst

In this paper, we introduce Flash-VL 2B, a novel approach to optimizing Vision-Language Models (VLMs) for real-time applications, targeting ultra-low latency and high throughput without sacrificing accuracy. Leveraging advanced…

计算机视觉与模式识别 · 计算机科学 2025-05-15 Bo Zhang , Shuo Li , Runhe Tian , Yang Yang , Jixin Tang , Jinhao Zhou , Lin Ma

Existing Multimodal Large Language Model (MLLM)-based agents face significant challenges in handling complex GUI (Graphical User Interface) interactions on devices. These challenges arise from the dynamic and structured nature of GUI…

Multi-modal Large Language Models (MLLMs) integrate visual and linguistic reasoning to address complex tasks such as image captioning and visual question answering. While MLLMs demonstrate remarkable versatility, MLLMs appears limited…

Multimodal Large Language Models (MLLMs) have experienced significant advancements recently. Nevertheless, challenges persist in the accurate recognition and comprehension of intricate details within high-resolution images. Despite being…

计算机视觉与模式识别 · 计算机科学 2024-03-05 Haogeng Liu , Quanzeng You , Xiaotian Han , Yiqi Wang , Bohan Zhai , Yongfei Liu , Yunzhe Tao , Huaibo Huang , Ran He , Hongxia Yang
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