相关论文: Normative Modeling for AD Diagnosis and Biomarker …
Objective: this study has a twofold goal. First, it aims to improve the understanding of the impact of Dementia of type Alzheimer's Disease (AD) on different aspects of the lexicon. Second, it aims to demonstrate that such aspects of the…
Alzheimer's disease (AD) is a progressive neurodegenerative disorder and the leading cause of dementia, affecting memory, reasoning, communication, and daily functioning. Early diagnosis is particularly important, as timely intervention may…
Early diagnosis of Alzheimer's Disease (AD) is crucial for delaying its progression. While AI-based speech detection is non-invasive and cost-effective, it faces a critical data efficiency dilemma due to medical data scarcity and privacy…
Deep learning based methods for medical images can be easily compromised by adversarial examples (AEs), posing a great security flaw in clinical decision-making. It has been discovered that conventional adversarial attacks like PGD which…
Alzheimer's disease is estimated to affect around 50 million people worldwide and is rising rapidly, with a global economic burden of nearly a trillion dollars. This calls for scalable, cost-effective, and robust methods for detection of…
Clinical data is often affected by clinically irrelevant factors such as discrepancies between measurement devices or differing processing methods between sites. In the field of machine learning (ML), these factors are known as domains and…
Volume change measures derived from longitudinal MRI (e.g. hippocampal atrophy) are a well-studied biomarker of disease progression in Alzheimer's Disease (AD) and are used in clinical trials to track the therapeutic efficacy of…
Identifying specific anatomical structures (\textit{e.g.}, lesions or landmarks) in medical images plays a fundamental role in medical image analysis. Exemplar-based landmark detection methods are receiving increasing attention since they…
Early detection is a crucial goal in the study of Alzheimer's Disease (AD). In this work, we describe several techniques to boost the performance of 3D deep convolutional neural networks (CNNs) trained to detect AD using structural brain…
Imaging and genomic data offer distinct and rich features, and their integration can unveil new insights into the complex landscape of diseases. In this study, we present a novel approach utilizing radiogenomic data including structural MRI…
Alzheimer's disease is a progressive neurological disorder characterized by cognitive impairment and memory loss. With the increasing aging population, the incidence of AD is continuously rising, making early diagnosis and intervention an…
Accurate diagnosis of Alzheimer's disease (AD) is both challenging and time consuming. With a systematic approach for early detection and diagnosis of AD, steps can be taken towards the treatment and prevention of the disease. This study…
Early prediction of Alzheimer's disease (AD) is crucial for timely intervention and treatment. This study aims to use machine learning approaches to analyze longitudinal electronic health records (EHRs) of patients with AD and identify…
Brain functional connectivity (FC) reveals biomarkers for identification of various neuropsychiatric disorders. Recent application of deep neural networks (DNNs) to connectome-based classification mostly relies on traditional convolutional…
The application of causal discovery to diseases like Alzheimer's (AD) is limited by the static graph assumptions of most methods; such models cannot account for an evolving pathophysiology, modulated by a latent disease pseudotime. We…
In Federated Learning (FL), anomaly detection (AD) is a challenging task due to the decentralized nature of data and the presence of non-IID data distributions. This study introduces a novel federated threshold calculation method that…
Reliable detection of the prodromal stages of Alzheimer's disease (AD) remains difficult even today because, unlike other neurocognitive impairments, there is no definitive diagnosis of AD in vivo. In this context, existing research has…
The diagnosis of early stages of Alzheimer's disease (AD) is essential for timely treatment to slow further deterioration. Visualizing the morphological features for the early stages of AD is of great clinical value. In this work, a novel…
Mild Cognitive Impairment (MCI) serves as a prodromal stage of Alzheimer's Disease (AD), where early identification and intervention can effectively slow the progression to dementia. However, diagnosing AD remains a significant challenge in…
Adversarial learning is a widely used technique in fair representation learning to remove the biases on sensitive attributes from data representations. It usually requires to incorporate the sensitive attribute labels as prediction targets.…