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Brain aging involves structural and functional changes and therefore serves as a key biomarker for brain health. Combining structural magnetic resonance imaging (sMRI) and functional magnetic resonance imaging (fMRI) has the potential to…

计算机视觉与模式识别 · 计算机科学 2024-12-10 Abd Ur Rehman , Azka Rehman , Muhammad Usman , Abdullah Shahid , Sung-Min Gho , Aleum Lee , Tariq M. Khan , Imran Razzak

Accurate estimation of biological brain age from three dimensional (3D) T$_1$-weighted magnetic resonance imaging (MRI) is a critical imaging biomarker for identifying accelerated aging associated with neurodegenerative diseases. Effective…

图像与视频处理 · 电气工程与系统科学 2025-08-05 Mehreen Kanwal , Yunsik Son

While unsupervised variational autoencoders (VAE) have become a powerful tool in neuroimage analysis, their application to supervised learning is under-explored. We aim to close this gap by proposing a unified probabilistic model for…

机器学习 · 计算机科学 2019-07-15 Qingyu Zhao , Ehsan Adeli , Nicolas Honnorat , Tuo Leng , Kilian M. Pohl

Objective: fMRI and derived measures such as functional connectivity (FC) have been used to predict brain age, general fluid intelligence, psychiatric disease status, and preclinical neurodegenerative disease. However, it is not always…

Numerous studies have established that estimated brain age, as derived from statistical models trained on healthy populations, constitutes a valuable biomarker that is predictive of cognitive decline and various neurological diseases. In…

计算机视觉与模式识别 · 计算机科学 2019-07-02 Xinyang Feng , Zachary C. Lipton , Jie Yang , Scott A. Small , Frank A. Provenzano

The determination of biological brain age is a crucial biomarker in the assessment of neurological disorders and understanding of the morphological changes that occur during aging. Various machine learning models have been proposed for…

图像与视频处理 · 电气工程与系统科学 2023-06-12 Mansoor Ahmed , Usama Sardar , Sarwan Ali , Shafiq Alam , Murray Patterson , Imdad Ullah Khan

Purpose: To develop an age prediction model which is interpretable and robust to demographic and technological variances in brain MRI scans. Materials and Methods: We propose a transformer-based architecture that leverages self-supervised…

计算机视觉与模式识别 · 计算机科学 2025-06-24 Pengyu Kan , Craig Jones , Kenichi Oishi

Missing input sequences are common in medical imaging data, posing a challenge for deep learning models reliant on complete input data. In this work, inspired by MultiMAE [2], we develop a masked autoencoder (MAE) paradigm for multi-modal,…

计算机视觉与模式识别 · 计算机科学 2026-02-04 Ayhan Can Erdur , Christian Beischl , Daniel Scholz , Jiazhen Pan , Benedikt Wiestler , Daniel Rueckert , Jan C Peeken

Normative modelling is an emerging method for understanding the underlying heterogeneity within brain disorders like Alzheimer Disease (AD) by quantifying how each patient deviates from the expected normative pattern that has been learned…

图像与视频处理 · 电气工程与系统科学 2026-02-06 Sayantan Kumar , Philip Payne , Aristeidis Sotiras

Normative modeling is an emerging and promising approach to effectively study disorder heterogeneity in individual participants. In this study, we propose a novel normative modeling method by combining conditional variational autoencoder…

机器学习 · 计算机科学 2022-11-17 Xuetong Wang , Kanhao Zhao , Rong Zhou , Alex Leow , Ricardo Osorio , Yu Zhang , Lifang He

Elucidating the functional mechanisms of the primary visual cortex (V1) remains a fundamental challenge in systems neuroscience. Current computational models face two critical limitations, namely the challenge of cross-modal integration…

神经元与认知 · 定量生物学 2024-12-20 Yu Zhu , Bo Lei , Chunfeng Song , Wanli Ouyang , Shan Yu , Tiejun Huang

A clear need for automatic anomaly detection applied to automotive testing has emerged as more and more attention is paid to the data recorded and manual evaluation by humans reaches its capacity. Such real-world data is massive, diverse,…

机器学习 · 计算机科学 2024-11-22 Lucas Correia , Jan-Christoph Goos , Philipp Klein , Thomas Bäck , Anna V. Kononova

Learning a robust Variational Autoencoder (VAE) is a fundamental step for many deep learning applications in medical image analysis, such as MRI synthesizes. Existing brain VAEs predominantly focus on single-modality data (i.e., T1-weighted…

计算机视觉与模式识别 · 计算机科学 2026-04-08 Mingjie Li , Edward Kim , Yue Zhao , Ehsan Adeli , Kilian M. Pohl

We present a new method for improving the performances of variational autoencoder (VAE). In addition to enforcing the deep feature consistent principle thus ensuring the VAE output and its corresponding input images to have similar deep…

计算机视觉与模式识别 · 计算机科学 2019-06-06 Xianxu Hou , Ke Sun , Linlin Shen , Guoping Qiu

Lesion detection in brain Magnetic Resonance Images (MRIs) remains a challenging task. MRIs are typically read and interpreted by domain experts, which is a tedious and time-consuming process. Recently, unsupervised anomaly detection (UAD)…

图像与视频处理 · 电气工程与系统科学 2022-02-01 Marcel Bengs , Finn Behrendt , Max-Heinrich Laves , Julia Krüger , Roland Opfer , Alexander Schlaefer

Brain aging is a regional phenomenon, a facet that remains relatively under-explored within the realm of brain age prediction research using machine learning methods. Voxel-level predictions can provide localized brain age estimates that…

计算机视觉与模式识别 · 计算机科学 2024-04-26 Neha Gianchandani , Mahsa Dibaji , Johanna Ospel , Fernando Vega , Mariana Bento , M. Ethan MacDonald , Roberto Souza

Time series sequence prediction and modelling has proven to be a challenging endeavor in real world datasets. Two key issues are the multi-dimensionality of data and the interaction of independent dimensions forming a latent output signal,…

机器学习 · 计算机科学 2020-10-09 Jakob Aungiers

Understanding relationships across multiple imaging modalities is central to neuroimaging research. We introduce the Integrative Variational Autoencoder (InVA), the first hierarchical VAE framework for image-on-image regression in…

图像与视频处理 · 电气工程与系统科学 2025-09-15 Bowen Lei , Yeseul Jeon , Rajarshi Guhaniyogi , Aaron Scheffler , Bani Mallick , Alzheimer's Disease Neuroimaging Initiatives

In medical imaging, anomaly detection is a vital element of healthcare diagnostics, especially for neurological conditions which can be life-threatening. Conventional deterministic methods often fall short when it comes to capturing the…

机器学习 · 计算机科学 2025-04-23 Dip Roy

Obesity is a common issue in modern societies today that can lead to various diseases and significantly reduced quality of life. Currently, research has been conducted to investigate resting state EEG (electroencephalogram) signals with an…

机器学习 · 计算机科学 2023-02-03 Yuan Yue , Jeremiah D. Deng , Dirk De Ridder , Patrick Manning , Divya Adhia
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