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相关论文: The Geometry of Codes for Random Access in DNA Sto…

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As DNA data storage moves closer to practical deployment, minimizing sequencing coverage depth is essential to reduce both operational costs and retrieval latency. This paper addresses the recently studied Random Access Problem, which…

信息论 · 计算机科学 2026-01-13 Chen Wang , Eitan Yaakobi

In this paper, we study the Random Access Problem in DNA storage, which addresses the challenge of retrieving a specific information strand from a DNA-based storage system. In this framework, the data is represented by $k$ information…

信息论 · 计算机科学 2025-08-26 Avital Boruchovsky , Ohad Elishco , Ryan Gabrys , Anina Gruica , Itzhak Tamo , Eitan Yaakobi

DNA data storage systems encode digital data into DNA strands, enabling dense and durable storage. Efficient data retrieval depends on coverage depth, a key performance metric. We study the random access coverage depth problem and focus on…

信息论 · 计算机科学 2025-07-29 Şeyma Bodur , Stefano Lia , Hiram H. López , Rati Ludhani , Alberto Ravagnani , Lisa Seccia

Motivated by DNA data storage, we study the expected number of coded symbols drawn from a linear code until a desired information symbol can be decoded - the random access expectation. We focus on generator matrices with a type of symmetry,…

信息论 · 计算机科学 2026-05-19 Christoph Hofmeister , Rawad Bitar , Eitan Yaakobi

We investigate the fundamental limits of the recently proposed random access coverage depth problem for DNA data storage. Under this paradigm, it is assumed that the user information consists of $k$ information strands, which are encoded…

信息论 · 计算机科学 2025-09-25 Anina Gruica , Daniella Bar-Lev , Alberto Ravagnani , Eitan Yaakobi

In this paper, we study achievable rates of concatenated coding schemes over a deoxyribonucleic acid (DNA) storage channel. Our channel model incorporates the main features of DNA-based data storage. First, information is stored on many,…

信息论 · 计算机科学 2020-05-04 Andreas Lenz , Lorenz Welter , Sven Puchinger

DNA codes have many applications, such as in data storage, DNA computing, etc. Good DNA codes have large sizes and satisfy some certain constraints. In this paper, we present a new construction method for reversible DNA codes. We show that…

信息论 · 计算机科学 2024-03-19 Xueyan Chen , Whan-Hyuk Choi , Hongwei Liu

This work presents a theoretical analysis of the probability of successfully retrieving data encoded with MDS codes (e.g., Reed-Solomon codes) in DNA storage systems. We study this probability under independent and identically distributed…

信息论 · 计算机科学 2026-05-08 Serge Kas Hanna

Hinging on ideas from physical-layer network coding, some promising proposals of coded random access systems seek to improve system performance (while preserving low complexity) by means of packet repetitions and decoding of linear…

信息论 · 计算机科学 2018-05-30 Adriano Pastore , Paul de Kerret , Monica Navarro , David Gregoratti , David Gesbert

Storing digital data in synthetic DNA faces challenges in ensuring data reliability in the presence of edit errors--deletions, insertions, and substitutions--that occur randomly during various stages of the storage process. Current…

信息论 · 计算机科学 2025-09-11 Serge Kas Hanna

DNA strings and their properties are widely studied since last 20 years due to its applications in DNA computing. In this area, one designs a set of DNA strings (called DNA code) which satisfies certain thermodynamic and combinatorial…

信息论 · 计算机科学 2025-10-03 Krishna Gopal Benerjee , Manish K Gupta

We describe the first DNA-based storage architecture that enables random access to data blocks and rewriting of information stored at arbitrary locations within the blocks. The newly developed architecture overcomes drawbacks of existing…

信息论 · 计算机科学 2015-05-12 S. M. Hossein Tabatabaei Yazdi , Yongbo Yuan , Jian Ma , Huimin Zhao , Olgica Milenkovic

Regenerating codes allow distributed storage systems to recover from the loss of a storage node while transmitting the minimum possible amount of data across the network. We present a systematic computer search for optimal systematic…

信息论 · 计算机科学 2009-10-14 Daniel Cullina , Alexandros G. Dimakis , Tracey Ho

We consider the problem of constructing an erasure code for storage over a network when the data sources are distributed. Specifically, we assume that there are n storage nodes with limited memory and k<n sources generating the data. We…

信息论 · 计算机科学 2016-11-15 Alexandros G. Dimakis , Vinod Prabhakaran , Kannan Ramchandran

We study the problem of coded information retrieval for block-structured data, motivated by DNA-based storage systems where a database is partitioned into multiple files that must each be recoverable as an atomic unit. We initiate and…

信息论 · 计算机科学 2026-03-19 Daniella Bar-Lev

We provide an overview of current approaches to DNA-based storage system design and accompanying synthesis, sequencing and editing methods. We also introduce and analyze a suite of new constrained coding schemes for both archival and random…

The genetic code has been shown to be very error robust compared to randomly selected codes, but to be significantly less error robust than a certain code found by a heuristic algorithm. We formulate this optimisation problem as a Quadratic…

定量方法 · 定量生物学 2015-03-13 Harry Buhrman , Peter T. S. van der Gulik , Steven M. Kelk , Wouter M. Koolen , Leen Stougie

DNA storage has emerged as an important area of research. The reliability of DNA storage system depends on designing the DNA strings (called DNA codes) that are sufficiently dissimilar. In this work, we introduce DNA codes that satisfy a…

信息论 · 计算机科学 2022-11-28 Krishna Gopal Benerjee , Sourav Deb , Manish K Gupta

In this paper, we propose a novel iterative encoding algorithm for DNA storage to satisfy both the GC balance and run-length constraints using a greedy algorithm. DNA strands with run-length more than three and the GC balance ratio far from…

信息论 · 计算机科学 2023-01-04 Seong-Joon Park , Yongwoo Lee , Jong-Seon No

The use of partial geometries to construct parity-check matrices for LDPC codes has resulted in the design of successful codes with a probability of error close to the Shannon capacity at bit error rates down to $10^{-15}$. Such…

信息论 · 计算机科学 2015-03-25 Qiuju Diao , Juane Li , Shu Lin , Ian Blake
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